Results 11 to 20 of about 11,853,684 (309)

Successful desensitization with 5-fluorouracil in a patient who developed anaphylaxis after 5-fluorouracil infusion

Alergologia Polska
5-Fluorouracil (5-FU) is a chemotherapeutic agent widely used in the treatment of gastrointestinal tract, skin and breast cancers. Hypersensitivity reactions may occur due to the use of chemotherapeutic drugs.
Mehmet Erdem Çakmak, Nida Oztop, Osman Ozan Yeğit   +2 more
doaj   +2 more sources

High incidence of Angina pectoris in patients treated with 5-fluorouracil - A planned surveillance study with 102 patients [PDF]

, 2003
Objective: Angina pectoris, arrhythmic sudden death and myocardial infarction, all these cardiac events have occasionally been reported during 5-fluorouracil (5-FU) chemotherapy.
Lersch, C., Wacker, A., Scherpinski, U., Reindl, L., Seyfarth, M., Wacker, Annette;Lersch, Christian;Scherpinski, Ute;Reindl, Laurence;Seyfarth, Melchior, Wacker, A;Lersch, C;Scherpinski, U;Reindl, L;Seyfarth, M   +6 more
core   +1 more source

Curcumin Chemosensitizes 5-Fluorouracil Resistant MMR-Deficient Human Colon Cancer Cells in High Density Cultures [PDF]

, 2014
Objective Treatment of colorectal cancer (CRC) remains a clinical challenge, as more than 15% of patients are resistant to 5-Fluorouracil (5-FU)-based chemotherapeutic regimens, and tumor recurrence rates can be as high as 50–60%.
Patricia Kraehe, Kraehe Patricia, Shayan, Parviz, Lueders, Cora, Shayan Parviz, Lueders Cora, Shakibaei Mehdi, Mehdi Shakibaei, Parviz Shayan, Goel Ajay, Buhrmann Constanze, Ajay Goel, Cora Lueders, Shakibaei, Mehdi, Constanze Buhrmann, Buhrmann, Constanze, Goel, Ajay, Kraehe, Patricia   +17 more
core   +1 more source

Topical application of 5-fluorouracil on attic cholesteatoma results in downregulation of keratinocyte growth factor and reduction of proliferative activity. [PDF]

, 2008
To investigate the cell-biological effect of topically applied 5-fluorouracil (5-FU) on middle ear cholesteatoma, 12 attic cholesteatomas were treated with topical application of 5-FU cream, two to five times with an interval of 2 weeks (5-FU group). The
Hishikawa, Yoshitaka, Terakado, Mariko, Takahashi, Haruo, Yoshitaka Hishikawa, Haruo Takahashi, Takehiko Koji, Mariko Terakado, Yamamoto-Fukuda, Tomomi, Koji, Takehiko, Tomomi Yamamoto-Fukuda   +9 more
core   +1 more source

Pharmacoeconomic analysis of adjuvant oral capecitabine vs intravenous 5-FU/LV in Dukes' C colon cancer: the X-ACT trial [PDF]

, 2006
Oral capecitabine (Xeloda^®) is an effective drug with favourable safety in adjuvant and metastatic colorectal cancer.
F Coxon, T S Maughan, Douillard, J.Y., Lesniewski-Kmak, K, Bertetto, O., Jelic, S., Maughan, T.S., Dufour, A., J-Y Douillard, Johnston, P G, C Twelves, Díaz-Rubio, E., Cassidy, J, Twelves, C., Jelic, S, P G Johnston, Figer, A, G Fountzilas, W Scheithauer, Patel, K K, Malzyner, A, Fountzilas, G., K Lesniewski-Kmak, A Malzyner, Maughan, TS, Bustová, I, Cowell, W., Garrison, L.P., Twelves, C, Díaz-Rubio, E, O Bertetto, W Cowell, Beham, A, S Jelic, Maughan, Tim, Dufour, P, J J McKendrick, Scheithauer, W., Douillard, JY, Cowell, W, Lesniewski-Kmak, K., Garrison, L P, Bustová, I., Beham, A., Fountzilas, G, Johnston, PG, A Beham, Garrison, LP, K K Patel, Patel, KK, I Bustová, Cassidy, J., McKendrick, J.J., Bertetto, O, L P Garrison, Coxon, F., Patel, K.K., Douillard, J-Y, P Dufour, A Figer, Johnston, P.G., Scheithauer, W, Coxon, F, Maughan, T S, McKendrick, JJ, J Cassidy, E Díaz-Rubio, McKendrick, J J, Malzyner, A., Figer, A.   +69 more
core   +1 more source

Kidney- and Site-Selective Delivery of 5-Fluorouracil Utilizing the Absorption on the Kidney Surface in Rats [PDF]

, 2002
The present study was undertaken to elucidate the kidney- and site-selective delivery of 5-fluorouracil (5-FU) utilizing the absorption on the kidney surface in rats.
Sasaki, Hitoshi, Horimoto, Tomomi, Mukai, Takahiro, Sakaeda, Toshiyuki, Hirayama, Ryu, Nakashima, Mikiro, Kawakami, Shigeru, Nishida, Koyo, Nakamura, Junzo   +8 more
core   +1 more source

Evolution of Adjuvant Chemotherapy and Efficacy of Commonly Used Regimens in Colorectal Cancer [PDF]

Al Ameen Journal of Medical Sciences, 2012
Objective: to know the evolution of adjuvant chemotherapy treatment given and to evaluate the efficacy of two commonly used regimens. Background: Colorectal cancer in Indian population is on upward swing due to the change in dietary habits and many other
S.M. Adiga, K. Meena Kumari, K.L. Bairy, M. Amberkar, B.M.Vadiraja, M.S.Vidyasagar   +5 more
doaj  

Corneal Epithelial Hyperplasia after 5-Fluorouracil Injection

Case Reports in Ophthalmology, 2018
Background: 5-Fluorouracil (5-FU) is a pyrimidine analogue which selectively inhibits DNA synthesis, RNA synthesis, and VEGF antibodies. 5-FU is widely used in ophthalmology for inhibition of postoperative corneal scarring and scleral bleb fibrosis. Case
Dania A. Bukhari, Sarah K. Alessa, Safaa I. Beheiri   +2 more
doaj   +1 more source

Rosiglitazone enhances the apoptotic effect of 5-fluorouracil in colorectal cancer cells with high-glucose-induced glutathione

Science Progress, 2020
Colorectal cancer is one of the most prevalent noncommunicable diseases worldwide. 5-Fluorouracil is the mainstay of chemotherapy for colorectal cancer.
Meng-Fei Lau, Kek-Heng Chua, Vikineswary Sabaratnam, Umah Rani Kuppusamy   +3 more
doaj   +1 more source

Specifics of Pharmacokinetics and Biodistribution of 5-Fluorouracil Polymeric Complex

Molecules, 2023
One of the promising and relevant directions in the treatment of oncological diseases is currently the development of a system for the delivery of antitumor drugs based on polyanions.
Olga V. Zhukova, Natalya A. Dubovskaya, Daria A. Zykova, Evgenia V. Arkhipova, Olga A. Vorobeva, Olga G. Zaborskaya, Sergey D. Zaitsev, Alexandra O. Grigoreva, Aleksandr A. Chicharov, Sergey A. Ryabov   +9 more
doaj   +1 more source