Results 11 to 20 of about 107,466 (267)

Successful outcomes of pediatric dacryocystorhinostomy with adjunctive 5-fluorouracil

open access: yesFrontiers in Ophthalmology
PurposeTo determine whether nasal intramucosal 5-fluorouracil (5-FU) injection improves outcomes after external dacryocystorhinostomy (DCR) in pediatric patients with nasolacrimal duct obstruction (NLDO).MethodsMulti-center retrospective non-comparative ...
Alina K. Sinha   +9 more
doaj   +1 more source

Corneal Epithelial Hyperplasia after 5-Fluorouracil Injection

open access: yesCase Reports in Ophthalmology, 2018
Background: 5-Fluorouracil (5-FU) is a pyrimidine analogue which selectively inhibits DNA synthesis, RNA synthesis, and VEGF antibodies. 5-FU is widely used in ophthalmology for inhibition of postoperative corneal scarring and scleral bleb fibrosis. Case
Dania A. Bukhari   +2 more
doaj   +1 more source

Rosiglitazone enhances the apoptotic effect of 5-fluorouracil in colorectal cancer cells with high-glucose-induced glutathione

open access: yesScience Progress, 2020
Colorectal cancer is one of the most prevalent noncommunicable diseases worldwide. 5-Fluorouracil is the mainstay of chemotherapy for colorectal cancer.
Meng-Fei Lau   +3 more
doaj   +1 more source

Specifics of Pharmacokinetics and Biodistribution of 5-Fluorouracil Polymeric Complex

open access: yesMolecules, 2023
One of the promising and relevant directions in the treatment of oncological diseases is currently the development of a system for the delivery of antitumor drugs based on polyanions.
Olga V. Zhukova   +9 more
doaj   +1 more source

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

open access: yesHepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou   +13 more
wiley   +1 more source

Cognitive impairment and elevated peripheral cytokines in breast cancer patients receiving chemotherapy

open access: yesArquivos de Neuro-Psiquiatria, 2022
Background Anthracyclines-based regimen (5-fluorouracil, doxorubicin, and cyclophosphamide (FAC); cyclophosphamide, epirubicin, and 5-fluorouracil [CEF]) and non-anthracycline based regimens (cyclophosphamide, methotrexate, and 5-fluorouracil [
Mohd Ashif Khan   +4 more
doaj   +1 more source

Insights into the involvement of noncoding RNAs in 5-fluorouracil drug resistance

open access: yesTumor Biology, 2017
5-Fluorouracil is a classic chemotherapeutic drug that is widely used to treat various cancers. However, patients often exhibit primary or acquired drug resistance during treatment with 5-fluorouracil chemotherapy.
Jun Deng   +4 more
doaj   +1 more source

Intraoperative infiltration against topical application of 5-fluorouracil in pterygium treatment

open access: yesDelta Journal of Ophthalmology, 2017
Purpose The aim of this study was to compare the efficacy and safety of intraoperative infiltration versus topical application of 5-fluorouracil (5-FU) as an adjuvant drug in pterygium treatment.
Basem M Ibrahim, Waled M Nada
doaj   +1 more source

Cardiotoxicity of 5-fluorouracil and capecitabine in Chinese patients: a prospective study

open access: yesCancer Communications, 2018
Background 5-Fluorouracil (5-FU) and capecitabine-associated cardiotoxicity ranging from asymptomatic electrocardiography (ECG) abnormalities to severe myocardial infarction has been reported in a number of studies, but such cardiotoxicity in Chinese ...
Jianjun Peng   +15 more
doaj   +1 more source

5-Fluorouracil/Coumarin and 5-Fluorouracil/Chromone Hybrids: Synthesis and Drug-Likeness Modeling

open access: yesMolbank
A series of 5-fluorouracil/coumarin and 5-fluorouracil/chromone hybrids were synthesized with good yields using click chemistry as the key step.
Laura Giraldo-Arroyave   +2 more
doaj   +1 more source

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