Evaluation of T-wave morphology parameters in drug-induced repolarization abnormalities [PDF]
This study evaluates the predictive values of T-wave morphology parameters reflecting the repolarization changes by beat to beat calculation of parameters using different mathematical tools to identify additional markers sensitive to the variation induced by drug in the surface of the electrocardiogram.
Khodor, Nadine+5 more
core +7 more sources
Abnormal lymphocyte function is secondary to drug-induced autoimmunity. [PDF]
Abnormal lymphocyte function has been frequently reported in patients with connective tissue diseases but its significance has been uncertain. Sequential studies of lymphocyte function were carried out in patients receiving the beta-adrenergic blocking drug practolol (Eraldin) both before and during the development of autoimmune complications.
E B Raftery+3 more
openaire +4 more sources
Liver Enzyme Abnormalities and Associated Risk Factors in HIV Patients on Efavirenz-Based HAART with or without Tuberculosis Co-Infection in Tanzania. [PDF]
To investigate the timing, incidence, clinical presentation, pharmacokinetics and pharmacogenetic predictors for antiretroviral and anti-tuberculosis drug induced liver injury (DILI) in HIV patients with or without TB co-infection.
A Habtewold+62 more
core +10 more sources
Imaging Features of Therapeutic Drug–induced Musculoskeletal Abnormalities [PDF]
Increasing use of a wide variety of therapeutic drugs with known musculoskeletal side-effect profiles necessitates a rigorous understanding and approach when evaluating imaging features suggestive of drug-induced musculoskeletal abnormalities. The etiology of such abnormalities is diverse, and the clinical and imaging manifestations may be nonspecific.
Venkatanarasimha, N+5 more
openaire +5 more sources
Phenotype standardization for drug-induced kidney disease. [PDF]
Drug-induced kidney disease is a frequent cause of renal dysfunction; however, there are no standards to identify and characterize the spectrum of these disorders.
Awdishu, Linda+8 more
core +7 more sources
Pauci-immune glomerulonephritis in individuals with disease associated with levamisole-adulterated cocaine: a series of 4 cases. [PDF]
Exposure to levamisole-adulterated cocaine can induce a distinct clinical syndrome characterized by retiform purpura and/or agranulocytosis accompanied by an unusual constellation of serologic abnormalities including antiphospholipid antibodies, lupus ...
Butcher, Brad+6 more
core +2 more sources
Thalidomide-induced Teratogenesis : History and Mechanisms [PDF]
Peer reviewedPublisher ...
Arlen RR+13 more
core +1 more source
Drug‑induced abnormalities of potassium metabolism
Pharmacotherapy has progressed rapidly over the last 20 years with the result that general practioners more and more often use drugs which may influence potassium metabolism at the kidney or gastrointestinal level, or the transmembrane transport of potassium at the cellular level.
Lidia Hyla-Klekot, Franciszek Kokot
openaire +3 more sources
The differential diagnosis of chorea [PDF]
Chorea is a hyperkinetic movement disorder characterised by excessive spontaneous movements that are irregularly timed, randomly distributed and abrupt. In this article, the authors discuss the causes of chorea, particularly Huntington's disease and the ...
Tabrizi, SJ, Wild, EJ
core +1 more source
Severe drug-induced liver injury associated with prolonged use of Linezolid [PDF]
This study aims to describe a patient developing concomitant severe liver failure and lactic acidosis after long-term treatment with linezolid. A 55-year-old Caucasian woman developed concomitant severe liver failure and lactic acidosis after a treatment
Benoit, Dominique+7 more
core +1 more source