Hydroxychloroquine-induced hyperpigmentation in a patient with anti-synthetase syndrome
Revista da Sociedade Portuguesa de Dermatologia e VenereologiaHydroxychloroquine is a widely prescribed antimalarial drug to treat immune-mediated diseases, with a good safety profile. We present the case of a 37-year-old woman, Fitzpatrick’s phototype IV, who presented to our outpatient Dermatology Department with
Claúdia Brazão +4 more
doaj
Improving treatment of glioblastoma: new insights in targeting cancer stem cells effectively [PDF]
, 2015 Glioblastoma is the most common primary malignant brain tumour in the adult population. Despite multimodality treatment with surgery, radiotherapy and chemotherapy, outcomes are very poor, with less than 15% of patients alive after two years ...
Mannino, Mariella
core
Advanced Functional Materials, EarlyView.A lack of standard approaches for testing and reporting the performance of metal halide perovskites and organic semiconductor radiation detectors has resulted in inconsistent interpretation of performance parameters, impeding progress in the field. This Perspective recommends key metrics and experimental details, which are suggested for reporting in ...
Jessie A. Posar +8 more
wiley +1 more source
Drug Points: Metabolic abnormality induced by streptomycin [PDF]
, 1994 Shmuel Fuchs +2 more
openalex +1 more source
The first-line antituberculosis drugs, and their fixed-dose combination induced abnormal sperm morphology and histological lesions in the testicular cells of male mice [PDF]
, 2022 Adekunle A. Bakare +11 more
openalex +1 more source
H2O2‐Generating Advanced Nanomaterials for Cancer Treatment
Advanced Functional Materials, EarlyView.H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie +8 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim +8 more
wiley +1 more source
Hydroxychloroquine Induced Cardiotoxicity: A Case Series
Romanian Journal of Internal MedicineHydroxychloroquine (HCQ) induced cardiotoxicity is a rare diagnosis and is often associated with chronic use of the medication. It has been shown that chronic HCQ use is associated with a drug-induced cardiomyopathy mainly driven by acquired lysosomal ...
Schneider Artur +7 more
doaj +1 more source
Persistent Liver Biochemistry Abnormalities Are More Common in Older Patients and those With Cholestatic Drug Induced Liver Injury [PDF]
, 2015 Robert J. Fontana +10 more
openalex +3 more sources
Flow‐Induced Vascular Remodeling on‐Chip: Implications for Anti‐VEGF Therapy
Advanced Functional Materials, EarlyView.Flow‐induced vascular remodeling plays a critical role in network stabilization and function. Using a vasculature‐on‐chip system, this study reveals how physiological VEGF levels and flow affect vascular remodeling and provides insights into tumor vessel normalization.
Fatemeh Mirzapour‐Shafiyi +6 more
wiley +1 more source