Results 51 to 60 of about 287,075 (253)

Indigenous Herbal Drug (Tinospora Cordifolia) Induced Liver Injury: A Case Report [PDF]

open access: yesBengal Physician Journal
Drug-induced liver injury (DILI) is a condition characterized by acute or chronic liver damage following the use of hepatotoxic drugs. It can be classified based on clinical presentation (hepatocellular, cholestasis, or mixed), mechanism of ...
Sounak Kumar Roy   +4 more
doaj   +1 more source

Drug-Induced Liver Injury in COVID-19 Patients: A Systematic Review

open access: yesFrontiers in Medicine, 2021
Introduction: The severity of COVID-19 may be correlated with the risk of liver injury development. An increasing number of studies indicate that degrees of hepatotoxicity has been associated with using some medications in the management of COVID-19 ...
F. Sodeifian   +7 more
semanticscholar   +1 more source

Aseptic meningitis, hepatitis and cholestasis induced by trimethoprim/sulfamethoxazole: a case report

open access: yesBMC Pediatrics, 2021
Background Drug-induced aseptic meningitis is a rare, but challenging diagnosis, most commonly reported with nonsteoroidal anti-inflammatory drugs (NSAIDs) and antibiotics.
J. A. A. van Asperdt, R. A. De Moor
doaj   +1 more source

Natural Products for Acetaminophen-Induced Acute Liver Injury: A Review

open access: yesMolecules, 2023
The liver plays a vital role in metabolism, synthesis, and detoxification, but it is susceptible to damage from various factors such as viral infections, drug reactions, excessive alcohol consumption, and autoimmune diseases.
Xiaoyangzi Li   +6 more
doaj   +1 more source

Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

open access: yesScientific Reports, 2016
Liver biology and function, drug-induced liver injury (DILI) and liver diseases are difficult to study using current in vitro models such as primary human hepatocyte (PHH) monolayer cultures, as their rapid de-differentiation restricts their usefulness ...
Catherine C. Bell   +18 more
semanticscholar   +1 more source

Immune-Mediated Drug-Induced Liver Injury: Immunogenetics and Experimental Models

open access: yesInternational Journal of Molecular Sciences, 2021
Drug-induced liver injury (DILI) is a challenging clinical event in medicine, particularly because of its ability to present with a variety of phenotypes including that of autoimmune hepatitis or other immune mediated liver injuries.
A. Gerussi   +8 more
semanticscholar   +1 more source

Impact of Non-Alcoholic Simple Fatty Liver Disease on Antituberculosis Drug-Induced Liver Injury

open access: yesInfection and Drug Resistance, 2021
Yi-Hui Liu,1 Yan Guo,2 Hong Xu,1 Hui Feng,1 Dong-Ya Chen1 1Department of Digestive Hepatology, Hangzhou Red Cross Hospital, Hangzhou, Zhejiang, 310003, People’s Republic of China; 2Department of Gastroenterology, Hangzhou Third Hospital, Hangzhou ...
Liu YH, Guo Y, Xu H, Feng H, Chen DY
doaj  

Drug-Induced Liver Injury: Clinical Evidence of N-Acetyl Cysteine Protective Effects

open access: yesOxidative Medicine and Cellular Longevity, 2021
Oxidative stress is a key pathological feature implicated in both acute and chronic liver diseases, including drug-induced liver injury (DILI).
Yonela Ntamo   +9 more
semanticscholar   +1 more source

Safety of drugs

open access: yesРепродуктивная эндокринология, 2018
Liver is the main organ that plays an important role in the biotransformation of medicine in human body. Therefore, drug-induced liver injuries are much more common than official medical statistics show in different countries and on different continents.
А. А. Суханова   +2 more
doaj   +1 more source

Inhibition of CYP1A1 Alleviates Colchicine-Induced Hepatotoxicity

open access: yesToxins
Colchicine, a natural compound extracted from Colchicum autumnale, is a phytotoxin, but interestingly, it also has multiple pharmacological activities.
Ruoyue Huang   +5 more
doaj   +1 more source

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