Results 51 to 60 of about 524,198 (385)

Febuxostat-induced acute liver injury [PDF]

, 2016
Febuxostat is a unique xanthine oxidase inhibitor that was approved for the prevention of gout in the United States in 2009. Unlike allopurinol, febuxostat is not a nucleoside analogue and has a higher specificity for xanthine oxidase. Although this drug
Matt Bohm, Naga Chalasani, null null, Raj Vuppalanchi   +3 more
core   +2 more sources

Dietary Intake of Vegetables and Cooking Oil Was Associated With Drug-Induced Liver Injury During Tuberculosis Treatment: A Preliminary Cohort Study

Frontiers in Nutrition, 2021
Background and Purpose: Drug-induced liver injury is challenging during tuberculosis treatment. There is no epidemiological data investigating the relation between dietary intake and the risk of drug-induced liver injury during tuberculosis treatment ...
Jinyu Wang, Ke Xiong, Lei Xu, Chao Zhang, Shanliang Zhao, Yufeng Liu, Aiguo Ma   +6 more
doaj   +1 more source

Fluorescent probe for the imaging of superoxide and peroxynitrite during drug-induced liver injury†

Chemical Science, 2021
Drug-induced liver injury (DILI) is an important cause of potentially fatal liver disease. Herein, we report the development of a molecular probe (LW-OTf) for the detection and imaging of two biomarkers involved in DILI.
Luling Wu, Jihong Liu, Xue Tian, Robin R. Groleau, S. Bull, Ping Li, Bo Tang, T. James   +7 more
semanticscholar   +1 more source

Epidemiology of drug-induced liver injury in a University Hospital from Colombia: Updated RUCAM being used for prospective causality assessment

Annals of Hepatology, 2019
Introduction and aim: Epidemiological information regarding drug-induced liver injury in some Latin American countries remains limited. Therefore, disease prevention and health promotion strategies are imperative to reduce drug-induced liver injuries and
Alejandra Cano-Paniagua, Pedro Amariles, Nancy Angulo, Margarita Restrepo-Garay   +3 more
doaj   +1 more source

Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

Scientific Reports, 2016
Liver biology and function, drug-induced liver injury (DILI) and liver diseases are difficult to study using current in vitro models such as primary human hepatocyte (PHH) monolayer cultures, as their rapid de-differentiation restricts their usefulness ...
Catherine C. Bell, D. Hendriks, Sabrina M. L. Moro, Ewa C. S. Ellis, Joanne Walsh, A. Renblom, Lisa Fredriksson Puigvert, A. Dankers, F. Jacobs, J. Snoeys, R. Sison-Young, R. Jenkins, Å. Nordling, S. Mkrtchian, B. K. Park, N. Kitteringham, C. Goldring, V. M. Lauschke, M. Ingelman-Sundberg   +18 more
semanticscholar   +1 more source

Insuficiência Hepática Aguda Induzida pela Trazodona e Diazepam [PDF]

, 2016
Most antidepressant agents have the potential to cause liver injury, even at therapeutic doses. Nevertheless, drug-induced liver injury (DILI) from antidepressant agents is a rare event. There is no way to prevent idiopathic DILI, but the severity of the
Barroso, E, Carvalhana, S, Ferreira, P, Oliveira, A, Perdigoto, R, Resende, M   +5 more
core   +1 more source

Incidence and risk factors of anti‐tuberculosis drug induced liver injury (DILI): Large cohort study involving 4652 Chinese adult tuberculosis patients

Liver international (Print), 2021
Anti‐tuberculosis drugs remain as an important cause of drug‐induced liver injury (DILI) worldwide. Adverse drug reactions reduce the effectiveness of treatment. We aimed to determine the incidence and risk factors associated with anti‐tuberculosis DILI (
F. Jiang, Huadong Yan, Lili Liang, Jingyuan Du, Susu Jin, Shi-Gui Yang, Hongxia Wang, Ting Hu, Yuying Zhu, Guangming Wang, Yao-ren Hu, Ting Cai, G. Aithal   +12 more
semanticscholar   +1 more source

Knowledge Mapping of Drug-Induced Liver Injury: A Scientometric Investigation (2010–2019)

Frontiers in Pharmacology, 2020
Background Drug-induced liver injury (DILI) is a common adverse event, which compromises the safety of numerous drugs, poses a significant risk to patient health, and enhances healthcare expenditures.
Lixin Ke, Cuncun Lu, Rui Shen, Ting-ting Lu, B. Ma, Y. Hua   +5 more
semanticscholar   +1 more source

A four-month gatifloxacin-containing regimen for treating tuberculosis. [PDF]

, 2014
BACKGROUND: Shortening the course of treatment for tuberculosis would be a major improvement for case management and disease control. This phase 3 trial assessed the efficacy and safety of a 4-month gatifloxacin-containing regimen for treating rifampin ...
Amukoye, Evans, Bah, Boubacar, de Jong, Bouke C, Fielding, Katherine, Gninafon, Martin, Horton, John, Kassa, Ferdinand, Lapujade, Olivier, Lienhardt, Christian, Lo, Mame B, Merle, Corinne S, Mthiyane, Thuli, N'Diaye, Alimatou, Odhiambo, Joseph, OFLOTUB/Gatifloxacin for Tuberculosis Project, Olliaro, Piero L, Perronne, Christian, Rustomjee, Roxana, Sismanidis, Charalambos, Sow, Omou Bah   +19 more
core   +1 more source

Indigenous Herbal Drug (Tinospora Cordifolia) Induced Liver Injury: A Case Report [PDF]

Bengal Physician Journal
Drug-induced liver injury (DILI) is a condition characterized by acute or chronic liver damage following the use of hepatotoxic drugs. It can be classified based on clinical presentation (hepatocellular, cholestasis, or mixed), mechanism of ...
Sounak Kumar Roy, Muniruddin SK, Subham Mondal, Sandipan Mukherjee, Santa Subhra Chatterjee   +4 more
doaj   +1 more source