Results 1 to 10 of about 609,557 (266)

Gut–Liver Axis: Liver Sinusoidal Endothelial Cells Function as the Hepatic Barrier in Colitis-Induced Liver Injury

Frontiers in Cell and Developmental Biology, 2021
BackgroundBased on the gut–liver axis theory, a leaky gut can aggravate liver injury. However, clinical studies suggest that although gut mucosa damage is commonly observed in inflammatory bowel disease (IBD), it seldom leads to severe liver injury.
Yang Wang, Yang Wang, Yifan Zhang, Yifan Zhang, Yun Liu, Yun Liu, Jun Xu, Jun Xu, Jun Xu, Yulan Liu, Yulan Liu   +10 more
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Mechanisms of the TGF-β1/Smad3-signaling pathway in gender differences in alcoholic liver fibrosis

Journal of Physiological Sciences
The TGF-β1/Smad3-signaling pathway and gender differences were investigated in alcoholic liver fibrosis. Mice were divided into female normal, female model, male normal, and male model groups.
Xiaomin Hong, Sanqiang Li, Renli Luo, Mengli Yang, Junfei Wu, Shuning Chen, Siyu Zhu   +6 more
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Circulating Endothelial Progenitor Cells Present an Inflammatory Phenotype and Function in Patients With Alcoholic Liver Cirrhosis

Frontiers in Physiology, 2018
Background and Aim: Endothelial progenitor cells (EPCs) have been implicated in liver injury and repair. However, the phenotype and potential of these heterogenous EPCs remain elusive.
Savneet Kaur, Rashi Sehgal, Saggere M. Shastry, Geoffrey McCaughan, Helen M. McGuire, Helen M. McGuire, Helen M. McGuire, Barbara Fazekas St de Groth, Barbara Fazekas St de Groth, Shiv Sarin, Nirupma Trehanpati, Devanshi Seth, Devanshi Seth, Devanshi Seth, Devanshi Seth   +14 more
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Ceramide kinase-mediated C1P metabolism attenuates acute liver injury by inhibiting the interaction between KEAP1 and NRF2

Experimental and Molecular Medicine
Acute liver injury is the basis of the pathogenesis of diverse liver diseases. However, the mechanism underlying liver injury is complex and not completely understood. In our study, we revealed that CERK, which phosphorylates ceramide to produce ceramide-
Wei Dong, Qing Li, Xing Lu, Jianfeng Lan, Zhidong Qiu, Xuehong Wang, Junnan Wang, Xiaojiao Zheng, Sifan Chen, Chong Zhang, Junfei Jin   +10 more
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The liver injuries

Acta chirurgica Iugoslavica, 2010
The liver is the most commonly injured abdominal organ. Severe hepatic trauma continue to be associated with high mortality. Management of liver injuries has changed significantly over the last two decades. Nonoperative management of hemodynamically stable patients has become the first treatment of choice.
Aleksandar Karamarkovic, Kristina Doklestic, Vladimir Djukic, Branislav Stefanovic, Dejan Radenkovic, Pavle Gregoric, Nenad Ivancevic, Zeljko Lausevic, Nada Popovic, Djordje Bajec   +9 more
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Apoptosis Induction of Lycorine on Lung Cancer NCI-H460 Cells and Related Mechanism

Zhongliu Fangzhi Yanjiu, 2018
Objective To investigate the effect of lycorine on the proliferation inhibition and apoptosis induction in human lung cancer NCI-H460 cells, and to explore the anti-tumor mechanism of lycorine.
LI Juwei, YANG Yang
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Hydrogel Loaded with Extracellular Vesicles: An Emerging Strategy for Wound Healing

Pharmaceuticals
An increasing number of novel biomaterials have been applied in wound healing therapy. Creating beneficial environments and containing various bioactive molecules, hydrogel- and extracellular vesicle (EV)-based therapies have respectively emerged as ...
Yucan Yang, Huizhi Chen, Yunjie Li, Junting Liang, Feng Huang, Liyan Wang, Huilai Miao, Himansu Sekhar Nanda, Jin Wu, Xinsheng Peng, Yubin Zhou   +10 more
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Hepatocellular carcinoma: pathogenesis, molecular mechanisms, and treatment advances

Frontiers in Oncology
Hepatocellular Carcinoma (HCC), a highly prevalent malignancy, poses a significant global health challenge. Its pathogenesis is intricate and multifactorial, involving a complex interplay of environmental and genetic factors.
Zhixian Ding, Zhixian Ding, Lusheng Wang, Lusheng Wang, Jiting Sun, Jiting Sun, Lijie Zheng, Lijie Zheng, Yu Tang, Yu Tang, Heng Tang, Heng Tang   +11 more
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Management of Traumatic Liver Injury in a Tertiary Care Hospital in Nepal

Journal of Nepal Health Research Council, 2020
Background: The liver is most frequently injured solid organ in abdominal trauma. The non-operative management is the standard treatment for hemodynamically stable patients.
Harish Chandra Neupane, Kishor Kumar Tamrakar, Abhishek Bhattrai, Tseten Yonjen Tamang, Bishnu Bista, Rajib Chaulagain   +5 more
doaj   +1 more source

LIVER INJURIES

The Professional Medical Journal, 2018
Objectives: To determine the role (frequency) of non-operative conservative management in liver injuries in blunt abdominal trauma. Methodology:.. Study Design: Descriptive study. Setting: Department of surgery Peoples University of Medical & Health Sciences Nawabshah. Period: 36 months extending from august 2014 to July 2017.
Shahnawaz Leghari, Gulshan Ali Memon, Habib ur Rehman Khan Toor   +2 more
openaire   +2 more sources