The uncoordinated-5 homolog B receptor affects hepatic ischemia reperfusion injury [PDF]
Recent evidence has demonstrated additional roles for the neuronal guidance protein receptor UNC5B outside the nervous system. Given the fact that ischemia reperfusion injury (IRI) of the liver is a common source of liver dysfunction and the role of ...
Tiago Granja (147967) +24 more
core +1 more source
GSH Attenuates Organ Injury and Improves Function after Transplantation of Fatty Livers [PDF]
Ischemia-reperfusion injury (IRI) is increased after transplantation of steatotic livers. Since those livers are increasingly used for transplantation, protective strategies must be developed. Reactive oxygen species (ROS) play a key role in hepatic IRI.
Jauch, Karl-Walter +15 more
core +1 more source
The study was to develop poly-γ-glutamic acid (γ-PGA)-coated Doxorubicin (Dox) lipoplexes that enhance the antitumor activity against liver tumors. γ-PGA-coated lipoplexes were performed by electrostatistically attracting to the surface of cationic ...
Na Qi, Bo Tang, Guang Liu, Xingsi Liang
doaj +1 more source
The incidence of liver injury in Uyghur patients treated for TB in Xinjiang Uyghur autonomous region, China, and its association with hepatic enzyme polymorphisms nat2, cyp2e1, gstm1 and gstt1. [PDF]
BACKGROUND AND OBJECTIVE: Of three first-line anti-tuberculosis (anti-TB) drugs, isoniazid is most commonly associated with hepatotoxicity. Differences in INH-induced toxicity have been attributed to genetic variability at several loci, NAT2, CYP2E1 ...
Ma, Jinfeng +50 more
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Background Evidences have indicated that miR-26a-5p regulates the malignant properties of various tumor cells. However, the influences of miR-26a-5p on proliferation, apoptosis and invasion are still vague in the cervical cancer (CC) cells.
Ming Li +7 more
doaj +1 more source
Minocycline decreases liver injury after hemorrhagic shock and resuscitation in mice [PDF]
Patients that survive hemorrhage and resuscitation (H/R) may develop a systemic inflammatory response syndrome (SIRS) that leads to dysfunction of vital organs (multiple organ dysfunction syndrome, MODS).
Zhong, Zhi +8 more
core +1 more source
Mechanism and suggestions of liver damage caused by influenza A virus: a narrative review [PDF]
This study aimed to explore the causes and mechanisms of liver damage caused by influenza A virus (IAV), compare the liver damage caused by SARS-CoV-2 and IAV under China’s Glasnost, propose treatment and vaccination recommendations for IAV, and provide ...
Y. Yin, R. Luo, S. Li, R. Li
doaj +1 more source
Herb-Induced Liver Injury by Ayurvedic Ashwagandha as Assessed for Causality by the Updated RUCAM: An Emerging Cause [PDF]
Herb-induced liver injury (HILI) caused by herbal supplements, natural products, and products used in traditional medicine are important for differential diagnoses in patients with acute liver injury without an obvious etiology.
Vidović, Bojana +14 more
core +1 more source
Can Viral Load Predict Liver Histology in Patients With Chronic Hepatitis B? [PDF]
Introduction: Hepatitis B virus (HBV) infection is a global public health problem. Serum HBV DNA measurement is a non-invasive test that predicts the liver disease progression.
Ashraf Karbasi +3 more
doaj +1 more source
Role of IRAK-M in Alcohol Induced Liver Injury [PDF]
Increasing evidence suggests that innate immunity plays an important role in alcohol-induced liver injury and most studies have focused on positive regulation of innate immunity.
Flavell, R.A. +8 more
core +1 more source

