Results 31 to 40 of about 965,195 (303)

MIF contributes to Trypanosoma brucei associated immunopathogenicity development [PDF]

, 2014
African trypanosomiasis is a chronic debilitating disease affecting the health and economic well-being of many people in developing countries. The pathogenicity associated with this disease involves a persistent inflammatory response, whereby M1-type ...
Beschin, Alain, Brys, Lea, Bucala, Richard, Caljon, Guy, De Baetselier, Patrick, Leng, Lin, Raes, Geert, Sparkes, Amanda, Stijlemans, Benoit, Van Den Abbeele, Jan, Van Ginderachter, Jo A, Vansintjan, Liese   +11 more
core   +4 more sources

Mechanism and suggestions of liver damage caused by influenza A virus: a narrative review [PDF]

Infectious Diseases and Tropical Medicine
This study aimed to explore the causes and mechanisms of liver damage caused by influenza A virus (IAV), compare the liver damage caused by SARS-CoV-2 and IAV under China’s Glasnost, propose treatment and vaccination recommendations for IAV, and provide ...
Y. Yin, R. Luo, S. Li, R. Li
doaj   +1 more source

The protective role of pregnane X receptor in lipopolysaccharide/D-galactosamine-induced acute liver injury. [PDF]

, 2010
The pregnane X receptor (PXR) is a nuclear receptor transcription factor regulating drug-metabolizing enzymes and transporters that facilitate xenobiotic and endobiotic detoxification.
Damjanov, Ivan, Wan, Yu-Jui Yvonne, Wang, Kun   +2 more
core   +2 more sources

Can Viral Load Predict Liver Histology in Patients With Chronic Hepatitis B? [PDF]

International Journal of Travel Medicine and Global Health, 2015
Introduction: Hepatitis B virus (HBV) infection is a global public health problem. Serum HBV DNA measurement is a non-invasive test that predicts the liver disease progression.
Ashraf Karbasi, Behzad Bafandeh, Seyed-Moayed Alavian, Amin Saburi   +3 more
doaj   +1 more source

Anti-tumor necrosis factor-alpha therapy during murine Klebsiella pneumoniae bacteremia: increased mortality in the absence of liver injury. [PDF]

, 2003
Klebsiella pneumoniae is a leading cause of gram-negative bacterial pneumonia, often resulting in bacteremia concurrent with the localized pulmonary infection.
Cogen, Anna L, Lau, Helen Y, Monteleon, Christine L, Moore, Thomas A, Standiford, Theodore J   +4 more
core   +1 more source

Mechanisms of isoniazid and rifampicin-induced liver injury and the effects of natural medicinal ingredients: A review

Frontiers in Pharmacology, 2022
Isoniazid (INH) and rifampicin (RFP) are the first-line medications for tuberculosis treatment, and liver injury is the major adverse effect. Natural medicinal ingredients provide distinct benefits in alleviating patients’ symptoms, lowering the liver ...
Xiuping Zhuang, Xiuping Zhuang, Li Li, Tianyi Liu, Rui Zhang, Peimin Yang, Xin Wang, Long Dai   +7 more
doaj   +1 more source

Liver involvement in pediatric celiac disease [PDF]

, 2015
Celiac disease (CD) is an intestinal inflammatory disease that manifests in genetically susceptible individuals when exposed to dietary gluten. It is a common chronic disorder, with a prevalence of 1% in Europe and North America.
Anania, Caterina, Chiesa, Claudio, De Castro, Giovanna, De Luca, Ester, Pacifico, Lucia   +4 more
core   +1 more source

Liver Injury Patterns and Hepatic Toxicity among People Living with and without HIV and Attending Care in Urban Uganda

International Journal of Hepatology, 2023
Introduction. The evaluation of the patterns of liver injury, derived from liver chemistry panels, often may narrow on probable causes of the liver insult especially when coupled with clinical history, examination, and other diagnostic tests.
Clara Wekesa, Rosalind Parkes-Ratanshi, Gregory D. Kirk, Ponsiano Ocama   +3 more
doaj   +1 more source

Association between vessels that encapsulate tumour clusters vascular pattern and hepatocellular carcinoma recurrence following liver transplantation

Frontiers in Oncology, 2022
BackgroundVessels that encapsulate tumor clusters (VETC) is a novel vascular pattern seen on hepatocellular carcinoma (HCC) histology which has been shown to independently predict tumor recurrence and survival after liver resection.
Claude Dennis, David S. Prince, David S. Prince, Leila Moayed-Alaei, Devika Remash, Emily Carr-Boyd, David G. Bowen, David G. Bowen, Simone I. Strasser, Simone I. Strasser, Michael Crawford, Carlo Pulitano, Carlo Pulitano, James Kench, James Kench, Geoffrey W. McCaughan, Geoffrey W. McCaughan, Geoffrey W. McCaughan, Catriona McKenzie, Catriona McKenzie, Ken Liu, Ken Liu, Ken Liu   +22 more
doaj   +1 more source

The role of human cytochrome P450 2E1 in liver inflammation and fibrosis. [PDF]

, 2017
Cytochrome P450 2E1 (CYP2E1) plays an important role in alcohol and toxin metabolism by catalyzing the conversion of substrates into more polar metabolites and producing reactive oxygen species.
Brenner, David A, Davidson, Nicholas O, Dennis, Edward A, Hu, Ronglin, Karin, Gabriel, Kisseleva, Tatiana, Koyama, Yukinori, Liang, Shuang, Ma, Hsiao-Yen, Quehenberger, Oswald, Sun, Mengxi, Xu, Jun   +11 more
core   +1 more source