Results 11 to 20 of about 618,743 (313)

Tests of Liver Injury [PDF]

Clinical Medicine & Research, 2004
Liver test abnormalities are commonly found in ambulatory patients now that these tests are routinely included in chemistry panels. The majority of asymptomatic patients with liver test abnormalities have no evidence of liver disease. Recognizing the different patterns of liver injury can be used as a guide to direct further evaluation of diseases that
Kenneth A, Musana, Steven H, Yale, Ahmad S, Abdulkarim   +2 more
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Vessels that encapsulate tumour clusters vascular pattern in hepatocellular carcinomaKey points

JHEP Reports, 2023
Summary: Vessels that encapsulate tumour clusters (VETC) is a distinct histologic vascular pattern associated with a novel mechanism of metastasis. First described in human cancers in 2004, its prevalence and prognostic significance in hepatocellular ...
Ken Liu, Claude Dennis, David S. Prince, Felix Marsh-Wakefield, Cositha Santhakumar, Jennifer R. Gamble, Simone I. Strasser, Geoffrey W. McCaughan   +7 more
doaj   +1 more source

Association of TM6SF2 rs58542926 T/C gene polymorphism with hepatocellular carcinoma: a meta-analysis

BMC Cancer, 2019
Background Hepatocellular carcinoma (HCC) is the sixth-most common malignancy worldwide. Multiple previous studies have assessed the relationship between TM6SF2 gene polymorphism and the risk of developing HCC, with discrepant conclusions reached.
Shan Tang, Jing Zhang, Ting-Ting Mei, Hai-Qing Guo, Xin-Huan Wei, Wen-Yan Zhang, Ya-Li Liu, Shan Liang, Zuo-Peng Fan, Li-Xia Ma, Wei Lin, Yi-Rong Liu, Li-Xia Qiu, Hai-Bin Yu   +13 more
doaj   +1 more source

Liver manipulation causes hepatocyte injury and precedes systemic inflammation in patients undergoing liver resection. [PDF]

, 2007
Contains fulltext : 51690.pdf (Publisher’s version ) (Closed access)BACKGROUND: Liver failure following liver surgery is caused by an insufficient functioning remnant cell mass.
Derikx, J.P.M., Peters, Wilbert H M, Poll, M.C. van de, Buurman, Wim A, Roelofs, H.M., Wigmore, S.J., Dejong, Cornelis H C, Roelofs, H.M.J., Derikx, Joep P M, Buurman, W.A., van de Poll, M., van de Poll, Marcel C G, Wigmore, Stephen J, Roelofs, Hennie M J, Dejong, C.H., Peters, W.H.M.   +15 more
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Glutathione treatment protects the rat liver against injury after warm ischemia and Kupffer cell activation [PDF]

, 2002
Background/Aim: The generation of reactive oxygen species by activated Kupffer cells (KC) may contribute to reperfusion injury of the liver during liver transplantation or resection.
Schauer, R., Rolf Schauer, Andreas Baron, Christian Steib, Ebensberger, S., Stefan Ebensberger, Manfred Bilzer, Steib, C., Alexander L. Gerbes, Baron, A., Bilzer, M., Gerbes, Alexander L.   +11 more
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Red blood cell distribution width: a determinant of hospital mortality in pancreatitis [PDF]

Journal of Emergency Practice and Trauma, 2018
Objective: In recent years, there has been a great attention concerning red blood cell distribution width (RDW) in clinical decisions as well as determining the severity of diseases.
Payman Moharamzadeh, Kavous Shahsavari Nia, Mohammadhossein Somi, Mahboub Pouraghaei, Akbar Fadaeihaghi, Farzad Rahmani   +5 more
doaj   +1 more source

Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice

Nature Communications, 2023
Parabacteroides distasonis (P. distasonis), part of the gut microbiome, was reported to play a role in diabetes, colorectal cancer and inflammatory bowel disease. Here the authors report that P.
Qi Zhao, Man-Yun Dai, Ruo-Yue Huang, Jing-Yi Duan, Ting Zhang, Wei-Min Bao, Jing-Yi Zhang, Shao-Qiang Gui, Shu-Min Xia, Cong-Ting Dai, Ying-Mei Tang, Frank J. Gonzalez, Fei Li   +12 more
doaj   +1 more source

Protocol TOP-Study (tacrolimus organ perfusion): a prospective randomized multicenter trial to reduce ischemia reperfusion injury in transplantation of marginal liver grafts with an "ex vivo" tacrolimus perfusion [PDF]

, 2013
Background: Critical organ shortage results in the utilization of extended donor criteria (EDC) liver grafts. These marginal liver grafts are prone to increased ischemia reperfusion injury (IRI) which may contribute to deteriorated graft function and ...
Jauch, Karl-Walter, Silvio Nadalin, Karl-Walter Jauch, Heise, Michael, Martin K Angele, Pratschke, Sebastian, Wolters, Heiner, Angele, Martin Kurt, Ulrich, Frank, Schemmer, Peter, Michael Heise, Dirk Wöhling, Angele, Martin K., Wöhling, Dirk, Sebastian Pratschke, Michael Eder, Nadalin, Silvio, Marcus N Scherer, Heiner Wolters, Andreas Pascher, Peter Schemmer, Scherer, Marcus N., Eder, Michael, Pascher, Andreas, Frank Ulrich   +24 more
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Defining the temporal evolution of gut dysbiosis and inflammatory responses leading to hepatocellular carcinoma in Mdr2 −/− mouse model

BMC Microbiology, 2021
Background Emerging evidence implicates the gut microbiome in liver inflammation and hepatocellular carcinoma (HCC) development. We aimed to characterize the temporal evolution of gut dysbiosis, in relation to the phenotype of systemic and hepatic ...
J. Behary, A. E. Raposo, N. M. L. Amorim, H. Zheng, L. Gong, E. McGovern, J. Chen, K. Liu, J. Beretov, C. Theocharous, M. T. Jackson, J. Seet-Lee, G. W. McCaughan, E. M. El-Omar, A. Zekry   +14 more
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Hypoxic Liver Injury [PDF]

Mayo Clinic Proceedings, 2006
Hypoxic liver injury is defined as a massive, but transient, increase in serum transaminase levels due to an imbalance between hepatic oxygen supply and demand in the absence of other acute causes of liver damage. It typically occurs in elderly individuals with right-sided congestive heart failure and low cardiac output.
openaire   +2 more sources