Results 161 to 170 of about 2,984,799 (310)

Extracting adverse drug reactions and their context using sequence labelling ensembles in TAC2017

, 2018
Adverse drug reactions (ADRs) are unwanted or harmful effects experienced after the administration of a certain drug or a combination of drugs, presenting a challenge for drug development and drug administration.
Belousov, Maksim, Dixon, William, Milosevic, Nikola, Nenadic, Goran   +3 more
core  

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

Advanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania, Manus J. P. Biggs, Katarzyna Krukiewicz   +2 more
wiley   +1 more source

Effectiveness and safety of protease inhibitors for the hepatitis C treatment in a hospital of South Brazil: real life data

Revista de Ciências Farmacêuticas Básica e Aplicada, 2020
Introduction: The combination of Inhibitors of protease boceprevir (BOC) or telaprevir (TLV) concomitantly with peginterferon (PEG) and ribavirin (RBV) constitute the triple therapy (TT) for Hepatitis C treatment. Objective: To describe the experience of
Aline Bianca Borba Mattana, Karin Hepp Schwambach, Alberi Adolfo Feltrin, Mareni Rocha Farias, Carine Raquel Blatt   +4 more
doaj  

Causal knowledge graph analysis identifies adverse drug effects [PDF]

arXiv
Knowledge graphs and structural causal models have each proven valuable for organizing biomedical knowledge and estimating causal effects, but remain largely disconnected: knowledge graphs encode qualitative relationships focusing on facts and deductive reasoning without formal probabilistic semantics, while causal models lack integration with ...
arxiv  

Supervised Adverse Drug Reaction Signalling Framework Imitating Bradford Hill's Causality Considerations [PDF]

Journal of Biomedical Informatics, 56 , pp. 356-368, 2015, 2016
Big longitudinal observational medical data potentially hold a wealth of information and have been recognised as potential sources for gaining new drug safety knowledge. Unfortunately there are many complexities and underlying issues when analysing longitudinal observational data. Due to these complexities, existing methods for large-scale detection of
arxiv  

Electroless Plating on Polymer Surfaces: Comprehensive Review of Mechanism, Process, Analysis, and Future Applications

Advanced Materials Interfaces, EarlyView.
This article provides a comprehensive overview of electroless plating, covering its basic mechanisms, bath composition, operating parameters, and metal layer characterization. It also addresses recent advancements, current limitations, and potential improvements, as well as the technology's applications in various industries.
Na Kyoung Kim, Seung Min Kang, Taegyun Kim, Suhyeon Kim, Geon Hwee Kim   +4 more
wiley   +1 more source

Introduction and reconciliation of the ROS and aging paradoxes [PDF]

arXiv, 2017
This paper suggests that aging is influenced synthetically by pro-aging factors such as ROS and anti-aging factors such as protective responses. The anti-aging effect may be side effects of retrograde responses motivated against adverse circumstances. ROS may be more closely correlated with metabolism rather than aging.
arxiv  

Current Advances of Antibacterial Biomaterials for Bone Regeneration

Advanced Materials Interfaces, EarlyView.
Effective treatment of infectious bone defects requires not only robust bone regeneration, but also the elimination of bacterial infection. This review highlights current cutting‐edge concepts and innovations in synthetic bone repair biomaterials and antibacterial bone repair materials, aiming to promote clinical translation and inspire broader ...
Xueping Kong, Xue Zhang, Ying Wang, Ben Zhang   +3 more
wiley   +1 more source

GASCADE: Grouped Summarization of Adverse Drug Event for Enhanced Cancer Pharmacovigilance [PDF]

arXiv
In the realm of cancer treatment, summarizing adverse drug events (ADEs) reported by patients using prescribed drugs is crucial for enhancing pharmacovigilance practices and improving drug-related decision-making. While the volume and complexity of pharmacovigilance data have increased, existing research in this field has predominantly focused on ...
arxiv  

Nanostructured 316L Stainless Steel Stent Surfaces Improve Corrosion Resistance, and Enhance Endothelization and Hemocompatibility

Advanced Materials Interfaces, EarlyView.
This study investigates the impact of nanostructured surface modification on corrosion resistance, HUVEC functions, and platelet interactions of 316L SS for cardiovascular stents. Nanostructured surfaces enhanced HUVEC proliferation, migration, and angiogenesis‐related gene expression while reducing platelet adhesion and hemolysis.
Yasar Kemal Erdogan, Pelin Mutlu, Batur Ercan   +2 more
wiley   +1 more source