Results 231 to 240 of about 2,984,799 (310)
Metal–Organic Frameworks: Unlocking New Frontiers in Cardiovascular Diagnosis and Therapy
Advanced Science, EarlyView.Metal–organic frameworks (MOFs), are composed of metal ions and bridging organic ligands, are recognized as an excellent platform for host‐gust chemistry. Its rich structural composition, modifiable sites, and multilevel pore distribution can provide delivery and release of signaling molecules, probes, and therapeutic drugs, which exhibit great medical
Qilu Wu +6 more
wiley +1 more source
Leprosy with comorbidities: A call for strengthening vigilance. [PDF]
J Family Med Prim CareRamasamy S, Panneerselvam S, Agrawal S.
europepmc +1 more source
Advanced Science, EarlyView.This work designs an in situ proliferating peptide nanoparticle as a flexible resolution that modulates the neuro‐glia unit to enable enhanced multi‐target combinational therapy for secondary brain damage following subarachnoid hemorrhage. Abstract Subarachnoid hemorrhage (SAH), a lethal stroke subtype, involves complex pathological cascades triggered ...
Yibin Zhang +8 more
wiley +1 more source
Advanced Science, EarlyView.This study presents decursin, a traditional Chinese medicine monomer, that inhibits lipid accumulation and inflammation in atherosclerosis through PKCδ interaction. A novel targeted delivery system (ALD@EM) is developed to overcome decursin's short half‐life, combining antibody‐mediated targeting, LDL‐facilitated chemotaxis, and enhanced macrophage ...
Hui Chen +13 more
wiley +1 more source
Balancing effectiveness, toxicity, and individualization: enfortumab vedotin in advanced urothelial cancer. [PDF]
Transl Androl UrolWang N, Tully KH.
europepmc +1 more source
Recent Advances in mRNA Delivery Systems for Cancer Therapy
Advanced Science, EarlyView.This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang +9 more
wiley +1 more source
Real-World pharmacovigilance analysis of drug-related conjunctivitis using the FDA adverse event reporting system database. [PDF]
Sci RepLi X, Sun YQ, Liu MM, Tang JF.
europepmc +1 more source
Advanced Science, EarlyView.This study develops TMEclassifier, a machine‐learning tool that classifies cancers into three distinct subtypes—Immune exclusive (IE), immune suppressive (IS), and immune activated (IA)—which exhibit significant heterogeneity and necessitate customized therapeutic strategies.
Dongqiang Zeng +27 more
wiley +1 more source