Results 161 to 170 of about 11,649,511 (362)
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez+5 more
wiley +1 more source
The effect of lowered muscle temperature on the action of neuromuscular blocking drugs in man
Thomas H. Cannard, Eleanor Zaimis
openalex +2 more sources
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee+9 more
wiley +1 more source
A Robust and Accurate Filter Paper-Based Dried Plasma Spot Method for Bictegravir Monitoring in HIV Therapy. [PDF]
Sathyanarayanan A+2 more
europepmc +1 more source
Commercial Drug Growing in the United States in 1918**Read before Scientific Section, A. Ph. A., New York meeting, 1919. [PDF]
W. W. Stockberger
openalex +1 more source
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan+4 more
wiley +1 more source
Potential Drug Dose-Specific Adverse Three-Drug Combinations: A US Insurance Claims Data-Based Study. [PDF]
Shi Y+12 more
europepmc +1 more source
DETECTION OF POISONS AND POWERFUL DRUGS [PDF]
WILHELM AUTENREITH, William H. Warren
openalex +1 more source