Results 11 to 20 of about 10,901,451 (408)
Drugging Drug Resistance [PDF]
Cell, 2010 Resistance to anticancer drugs is widely observed in vitro and in cancer patients, but its prevalence is too high to be solely explained by the acquisition of mutations. Sharma et al. (2010) now report that dynamic chromatin modifications may be an independent route to drug resistance in cancer cells that can be reversed by epigenetic drugs.
Anton Berns, Jan-Hermen Dannenberg
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The Journal of Medicine and Philosophy: A Forum for Bioethics and Philosophy of Medicine, 2023 AbstractDespite their centrality to medicine, drugs are not easily defined. We introduce two desiderata for a basic definition of medical drugs. It should: (a) capture everything considered to be a drug in medical contexts and (b) rule out anything that is not considered to be a drug.
Baron, Samuel +2 more
openaire +3 more sources
American Journal of Public Health, 1926 Report of Committee on Uniform Standard Milk Ordinance, Conference of State and Territorial Health Officers, 1926-A committee of 4 members, appointed by the 1925 Conference of State and Territorial Health Officers, was instructed to make a careful study of the so-called standard milk ordinance of the United States Public Health Service and submit a ...
openaire +37 more sources
Drug Use and Drug Policy [PDF]
Journal of Institutional and Theoretical Economics, 2002 Early in the twentieth century the Dutch East Indies (present-day Indonesia) had a government monopoly on the import, refining, and retailing of opium. There were regional differences in opium policy ranging from areas with prohibition to areas where opium use was hardly restricted.
Luijk, Eric W. van, Ours, Jan C. van
openaire +4 more sources
American Journal of Public Health, 1925 The Composition and Decomposition of Eggs-Miscellaneous data are reported on the composition of eggs, including particularly the percentage of fatty acids in fresh and stale egg yolk, analytical constants of the fat of hen's eggs, duck's eggs, and Chinese preserved egg yolk, and the reaction of egg yolk and white to indicators.-R. T.
openaire +27 more sources
Provenance-Centered Dataset of Drug-Drug Interactions [PDF]
, 2015 Over the years several studies have demonstrated the ability to identify potential drug-drug interactions via data mining from the literature (MEDLINE), electronic health records, public databases (Drugbank), etc.
A Callahan +14 more
core +3 more sources
Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2
Cell Discovery, 2020 Human coronaviruses (HCoVs), including severe acute respiratory syndrome coronavirus (SARS-CoV) and 2019 novel coronavirus (2019-nCoV, also known as SARS-CoV-2), lead global epidemics with high morbidity and mortality.
Yadi Zhou +5 more
semanticscholar +1 more source
The Cancer Cell Line Encyclopedia enables predictive modeling of anticancer drug sensitivity
Nature, 2012 The systematic translation of cancer genomic data into knowledge of tumour biology and therapeutic possibilities remains challenging. Such efforts should be greatly aided by robust preclinical model systems that reflect the genomic diversity of human ...
J. Barretina +60 more
semanticscholar +1 more source
Songklanakarin Journal of Science and Technology (SJST), 2022 The present review discusses the effects of pharmaceutical drugs on aquatic ecosystem, in particular the fish to be precise. The focus is on roles of multiple drug types like antimicrobial, antipsychotic, analgesic, and anti-inflammatory; and the ...
Drugs and Fish
doaj +1 more source
Hyperbolic Molecular Representation Learning for Drug Repositioning [PDF]
arXiv, 2022 Learning accurate drug representations is essential for task such as computational drug repositioning. A drug hierarchy is a valuable source that encodes knowledge of relations among drugs in a tree-like structure where drugs that act on the same organs, treat the same disease, or bind to the same biological target are grouped together.
arxiv