Results 11 to 20 of about 4,582,318 (310)
Drugging Drug Resistance [PDF]
Cell, 2010 Resistance to anticancer drugs is widely observed in vitro and in cancer patients, but its prevalence is too high to be solely explained by the acquisition of mutations. Sharma et al. (2010) now report that dynamic chromatin modifications may be an independent route to drug resistance in cancer cells that can be reversed by epigenetic drugs.
Dannenberg, Jan-Hermen, Berns, Anton
openaire +2 more sources
NOACs: drug–drug interactions [PDF]
Canadian Medical Association Journal, 2016 We commend Fralick and colleagues for their article on drug interactions with rivaroxaban.[1][1] All novel oral anticoagulants (NOACs) were introduced as at least noninferior (in some cases superior) to warfarin.
Bartosz, Hudzik +2 more
openaire +2 more sources
Strategy for applying utility model patents in clinical nursing (临床护理用具实用新型专利申请心得体会)
中西医结合护理, 2021 This paper summarized the strategy for applying utility model patents in clinical nursing. Issues about meaning of patent, application procedure and design inspiration were discussed and shared, in order to provide reference in design and application of ...
QIAO Shouang (乔首昂) +2 more
doaj +1 more source
Drug-Drug Interaction of Antifungal Drugs
YAKUGAKU ZASSHI, 2005 This article reviews the in vitro metabolic and the in vivo pharmacokinetic drug-drug interactions with antifungal drugs, including fluconazole, itraconazole, micafungin, miconazole, and voriconazole. In the in vitro interaction studies, the effects of antifungal drugs on specific activities of cytochrome P450s (CYPs), including CYP1A2, CYP2C9, CYP2C19,
Toshiro, Niwa +2 more
openaire +3 more sources
Pharmacodynamic Drug–Drug Interactions [PDF]
Clinical Pharmacology & Therapeutics, 2019 Pharmacodynamic drug–drug interactions (DDIs) occur when the pharmacological effect of one drug is altered by that of another drug in a combination regimen. DDIs often are classified as synergistic, additive, or antagonistic in nature, albeit these terms are frequently misused.
Jin, Niu +2 more
openaire +2 more sources
Changes in prescription drug abuse during the COVID-19 pandemic evidenced in the Catalan pharmacies
Frontiers in Public Health, 2023 IntroductionThe impact of a pandemic on the mental health of the population is to be expected due to risk factors such as social isolation. Prescription drug abuse and misuse could be an indicator of the impact of the COVID-19 pandemic on mental health ...
Maria Perelló +13 more
doaj +1 more source
Le médicament comme objet technique
Socio-anthropologie, 2021 Since drugs are used not only to treat patients, but also to transform human performances, this paradigm shift in medical practice blurs the lines between therapeutic medicine and so-called ameliorative or augmentative medicine.
Daniela Cerqui, Margaux Bressan
doaj +1 more source
Cardiovascular Therapeutics, 2009 Understanding and documentation of drug–drug interactions (DDIs) are an important component of drug development, and of clinical therapeutics. Because clinical DDI studies are costly, time‐consuming, and involve some risk, not all clinical DDI questions can be realistically addressed through human DDI trials.In vitromodels have been used to identify ...
openaire +2 more sources
DARU Journal of Pharmaceutical Sciences, 2012 Editorial Active pharmaceutical ingredients (APIs) are most conveniently developed and delivered orally as solid dosage forms that contain a defined crystalline form of an API. Co-crystal is a crystalline entity formed by two different or more molecular entities where the intermolecular interactions are weak forces like hydrogen bonding and π-π ...
openaire +2 more sources
Drug and Environment Parameters of Pharmacy Places [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2019 This study consists of two parts; the first part is measuring the temperature and relative humidity of twenty pharmacy shops and pharmacy refrigerators in Erbil city. The temperature inside nine types of different drug bottles is also measured.
Abdulrahman Suliman +4 more
doaj +1 more source