Results 11 to 20 of about 12,292,416 (404)
AbstractDespite their centrality to medicine, drugs are not easily defined. We introduce two desiderata for a basic definition of medical drugs. It should: (a) capture everything considered to be a drug in medical contexts and (b) rule out anything that is not considered to be a drug.
Baron, Samuel +2 more
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Drugging Drug Resistance [PDF]
Resistance to anticancer drugs is widely observed in vitro and in cancer patients, but its prevalence is too high to be solely explained by the acquisition of mutations. Sharma et al. (2010) now report that dynamic chromatin modifications may be an independent route to drug resistance in cancer cells that can be reversed by epigenetic drugs.
Anton Berns, Jan-Hermen Dannenberg
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Drug-related mutational patterns in hepatitis B virus (HBV) reverse transcriptase proteins from Iranian treatment-Naïve chronic HBV patients [PDF]
Background: Immunomodulators and Nucleotide analogues have been used globally for the dealing of chronic hepatitis B virus (HBV) infection. However, the development of drug resistance is a major limitation to their long-term effectiveness.
Abedi, F. +33 more
core +1 more source
Detecting a signal in the noise : Monitoring the global spread of novel psychoactive substances using media and other open source information [PDF]
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no ...
Canadian Community Epidemiology Network On Drug Use +3 more
core +1 more source
Drug Use and Drug Policy [PDF]
Early in the twentieth century the Dutch East Indies (present-day Indonesia) had a government monopoly on the import, refining, and retailing of opium. There were regional differences in opium policy ranging from areas with prohibition to areas where opium use was hardly restricted.
Luijk, Eric W. van, Ours, Jan C. van
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Report of Committee on Uniform Standard Milk Ordinance, Conference of State and Territorial Health Officers, 1926-A committee of 4 members, appointed by the 1925 Conference of State and Territorial Health Officers, was instructed to make a careful study of the so-called standard milk ordinance of the United States Public Health Service and submit a ...
openaire +37 more sources
The Composition and Decomposition of Eggs-Miscellaneous data are reported on the composition of eggs, including particularly the percentage of fatty acids in fresh and stale egg yolk, analytical constants of the fat of hen's eggs, duck's eggs, and Chinese preserved egg yolk, and the reaction of egg yolk and white to indicators.-R. T.
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Background: Osteoporosis is a major causative factor of the global burden of disease and disability, characterized by low bone mineral density (BMD) and high risks of fracture.
Zhichong Wu +17 more
doaj +1 more source
Customizing the therapeutic response of signaling networks to promote antitumor responses by drug combinations [PDF]
Drug resistance, de novo and acquired, pervades cellular signaling networks (SNs) from one signaling motif to another as a result of cancer progression and/or drug intervention.
Bown, James L. +4 more
core +4 more sources
Study on drug-induced parkinsonism and its clinical patterns in Eastern Indian population
Background: Drug-induced parkinsonism (DIP) is important as it is reversible if identified and treated early. We present herewith various clinical patterns and drugs commonly causing DIP.
Praveen Kumar Yadav
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