Results 201 to 210 of about 8,662,910 (358)

Metal organic frameworks as a drug delivery system for flurbiprofen

, 2017
Muder Al Hayder, Hussein Rasool Abid, Bruce Sunderland, Shaobin Wang   +3 more
openalex   +2 more sources

An antibacterial and proangiogenic double-layer drug-loaded microneedle patch for accelerating diabetic wound healing

, 2022
Shan Gao, Wanlin Zhang, Xingxing Zhai, Xue Zhao, Jianxin Wang, Jie Weng, Jianshu Li, Xingyu Chen   +7 more
openalex   +2 more sources

Key role for inhibins in effective T cell activation, migration and Th17 differentiation

FEBS Open Bio, EarlyView.
Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco, Roxana Olguín‐Alor, Lizbeth Bolaños‐Castro, Alexandra Morales‐Cruz, Marisol De La Fuente‐Granada, Gloria Soldevila   +5 more
wiley   +1 more source

Beyond QSARs: Quantitative Knowledge-Activity Relationships (QKARs) for enhanced drug toxicity prediction. [PDF]

Toxicol Sci
Li T, Qu Y, Chen A, Thakkar S, Li D, Tong W.   +5 more
europepmc   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Correction: An Evaluation of Duplicate Adverse Event Reports Characteristics in the Food and Drug Administration Adverse Event Reporting System. [PDF]

Drug Saf
Janiczak S, Tanveer S, Tom K, Zhang R, Ma Y, Wolf L, Muñoz MA.   +6 more
europepmc   +1 more source

Impact of gastrointestinal disease states on oral drug absorption – implications for formulation design – a PEARRL review [PDF]

, 2018
Angela Effinger, Caitríona M. O’Driscoll, Mark McAllister, Nikoletta Fotaki   +3 more
openalex   +1 more source

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

FEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu, Yumi Iwashita, Keisuke Tachibana, Itsuki Nishino, Yuki Niwa, Atsuko Uyeda, Kazuki Matsuo, Masahiro Nagahama, Masuo Kondoh   +8 more
wiley   +1 more source

The promise of cardiomyocyte computational models for drug safety. [PDF]

Mil Med Res
Wang L, Rodriguez B.
europepmc   +1 more source

Models of drug-induced liver injury for evaluation of phytotherapeutics and other natural products

, 2013
Hartmut Jaeschke, C. David Williams, Mitchell R. McGill, Yuchao Xie, Anup Ramachandran   +4 more
openalex   +1 more source