Results 21 to 30 of about 10,901,451 (408)

A Novel Canine Mammary Cancer Cell Line: Preliminary Identification and Utilization for Drug Screening Studies

open access: yesFrontiers in Veterinary Science, 2021
Canine malignant mammary tumor is a dangerously fatal neoplastic disease with poor survival in female dogs. The aim of this study was to preliminary characterize a novel canine mammary cancer cell line, B-CMT, from canine primary mammary gland tumor, and
Rifei Li   +6 more
doaj   +1 more source

The relationship between trait emotional intelligence and problematic alcohol use among college students [PDF]

open access: yesHealth Promotion Perspectives, 2022
Background: Problematic alcohol use among college students is a significant public health concern. Emotional intelligence (EI), or the ability to detect one’s own and others’ emotions and to use this information to direct behavior, is suggested to ...
Robert E Davis   +4 more
doaj   +1 more source

AMFPMC -- An improved method of detecting multiple types of drug-drug interactions using only known drug-drug interactions [PDF]

open access: yesarXiv, 2023
Adverse drug interactions are largely preventable causes of medical accidents, which frequently result in physician and emergency room encounters. The detection of drug interactions in a lab, prior to a drug's use in medical practice, is essential, however it is costly and time-consuming.
arxiv  

Greater than the Sum: Applying Daily-Dose Equivalents to Antipsychotic Prescription Claims to Study Real-World Effects

open access: yesFrontiers in Pharmacology, 2021
Traditional methods to standardize exposures in pharmacoepidemiologic studies, like defined daily-doses, may be inadequate to capture drug class effects when there are many in-class medications, formulations, and administration routes.
Kaleen N. Hayes   +8 more
doaj   +1 more source

NeuroCADR: Drug Repurposing to Reveal Novel Anti-Epileptic Drug Candidates Through an Integrated Computational Approach [PDF]

open access: yesarXiv, 2023
Drug repurposing is an emerging approach for drug discovery involving the reassignment of existing drugs for novel purposes. An alternative to the traditional de novo process of drug development, repurposed drugs are faster, cheaper, and less failure prone than drugs developed from traditional methods.
arxiv  

A New Metric Quantifying Chemical and Biological Property of Small Molecule Metabolites and Drugs

open access: yesFrontiers in Molecular Biosciences, 2020
One prominent class of drugs is chemical small molecules (CSMs), but the majority of CSMs are of very low druggable potential. Therefore, it is quite important to predict drug-related properties (druggable properties) for candidate CSMs.
Chuanbo Huang   +4 more
doaj   +1 more source

Molecular subtypes of osteosarcoma classified by cancer stem cell related genes define immunological cell infiltration and patient survival

open access: yesFrontiers in Immunology, 2022
Recent studies have shown that tumor stemness has biological significance in tumorigenicity and tumor progression. However, the characteristics of TME immune infiltration in osteosarcoma mediated by the combined effects of multiple cancer stem cell ...
Lei Guo   +17 more
doaj   +1 more source

Medical Knowledge Graph QA for Drug-Drug Interaction Prediction based on Multi-hop Machine Reading Comprehension [PDF]

open access: yes, 2022
Drug-drug interaction prediction is a crucial issue in molecular biology. Traditional methods of observing drug-drug interactions through medical experiments require significant resources and labor. This paper presents a medical knowledge graph question answering model, dubbed MedKGQA, that predicts drug-drug interaction by employing machine reading ...
arxiv   +1 more source

Pharmacokinetic Drug–Drug Interactions and Herb–Drug Interactions [PDF]

open access: yesPharmaceutics, 2021
Due to the growing use of herbal supplementation—ease of taking herbal supplements with therapeutics drugs (i [...]
Min-Koo Choi, Im-Sook Song
openaire   +4 more sources

Review of COVID-19 treatment

open access: yesJournal of Research in Pharmacy Practice, 2020
Many contagious diseases, such as plague or cholera, played a role in changing the pathway of history. In this respect, although coronavirus was not as dangerous as novel diseases such as swine flu and Ebola, the spread and the power of coronavirus ...
Somayeh Sadeghi   +3 more
doaj   +1 more source

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