Results 21 to 30 of about 8,662,910 (358)

MetroGel® V—A metronidazole vaginal preparation

open access: yesSouth African Family Practice, 2007
No abstract available.
Amayeza Drug Info Centre
doaj   +1 more source

Nanobiosystems for Antimicrobial Drug-Resistant Infections

open access: yesNanomaterials, 2021
The worldwide increased bacterial resistance toward antimicrobial therapeutics has led investigators to search for new therapeutic options. Some of the options currently exploited to treat drug-resistant infections include drug-associated nanosystems ...
Foteini Gkartziou   +3 more
doaj   +1 more source

Drug-drug interactions in repeat prescriptions at village dispensaries (bereg) in Malta [PDF]

open access: yes, 2013
Inappropriate treatments and drug-drug interactions (DDIs) are known to occur in settings where repeat prescriptions are issued. In view of this, a study was carried out to document any such problematic drug prescribing and propose changes that would
Bugeja, Anton
core  

Current Concepts on Drug Abuse and Dependence [PDF]

open access: yes, 2015
Drug addiction is a complex disease characterized by compulsive and uncontrollable desire to seek and consume the drug. In time, drug-related terminology has undergone many changes, arising from the deepening of the mechanisms of action, but also about ...
Baconi, Daniela Luiza   +5 more
core   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Synthesis of Coumarin and Homoisoflavonoid Derivatives and Analogs: The Search for New Antifungal Agents

open access: yesPharmaceuticals, 2022
A set of twenty-four synthetic derivatives, with coumarin and homoisoflavonoid cores and structural analogs, were submitted for evaluation of antifungal activity against various species of Candida.
Alana R. Ferreira   +4 more
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

Drug Possession Arrests Reported in Alaska, 1986–2017 [PDF]

open access: yes, 2018
Underlying data is available in both Excel and PDF format. (Download below.)This fact sheet presents data on drug sale possession arrests reported by Alaska law enforcement agencies for the 32-year period 1986 to 2017. Overall, the drug possession arrest
Ervin, Benjamin
core  

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Delabelling multiple antibiotic allergy: Practical issues

open access: yesFrontiers in Allergy, 2023
With the growing incidence of multi-drug resistant organisms, delabelling incorrect antibiotic allergies has become an integral part of antimicrobial stewardship worldwide.
Philip Hei Li, Bernard Yu-Hor Thong
doaj   +1 more source

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