Results 21 to 30 of about 11,649,511 (362)

Drug Use and Drug Policy [PDF]

open access: yesJournal of Institutional and Theoretical Economics, 2002
Early in the twentieth century the Dutch East Indies (present-day Indonesia) had a government monopoly on the import, refining, and retailing of opium. There were regional differences in opium policy ranging from areas with prohibition to areas where opium use was hardly restricted.
Luijk, Eric W. van, Ours, Jan C. van
openaire   +4 more sources

The Cancer Cell Line Encyclopedia enables predictive modeling of anticancer drug sensitivity

open access: yesNature, 2012
The systematic translation of cancer genomic data into knowledge of tumour biology and therapeutic possibilities remains challenging. Such efforts should be greatly aided by robust preclinical model systems that reflect the genomic diversity of human ...
J. Barretina   +60 more
semanticscholar   +1 more source

Recent updates on incubation of drug craving: a mini-review [PDF]

open access: yes, 2015
Cue-induced drug craving progressively increases after prolonged withdrawal from drug self-administration in laboratory animals, a behavioral phenomenon termed 'incubation of drug craving.' Studies over the years have revealed several important neural ...
Abdolahi   +39 more
core   +1 more source

Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2

open access: yesCell Discovery, 2020
Human coronaviruses (HCoVs), including severe acute respiratory syndrome coronavirus (SARS-CoV) and 2019 novel coronavirus (2019-nCoV, also known as SARS-CoV-2), lead global epidemics with high morbidity and mortality.
Yadi Zhou   +5 more
semanticscholar   +1 more source

Customizing the therapeutic response of signaling networks to promote antitumor responses by drug combinations [PDF]

open access: yes, 2014
Drug resistance, de novo and acquired, pervades cellular signaling networks (SNs) from one signaling motif to another as a result of cancer progression and/or drug intervention.
Bown, James L.   +4 more
core   +3 more sources

‘Initiation into drug use’ addendum: findings from the DUMA program [PDF]

open access: yes, 2012
The age at which an individual first experiments with illicit drugs has been of significant interest to policymakers and practitioners, primarily because research has persistently shown a link between early juvenile onset of drug use and less favourable ...
Jason Payne, Josh Sweeney
core   +1 more source

TCMSP: a database of systems pharmacology for drug discovery from herbal medicines

open access: yesJournal of Cheminformatics, 2014
BackgroundModern medicine often clashes with traditional medicine such as Chinese herbal medicine because of the little understanding of the underlying mechanisms of action of the herbs. In an effort to promote integration of both sides and to accelerate
Jinlong Ru   +13 more
semanticscholar   +1 more source

Mechanisms of burst release from pH-responsive polymeric microparticles. [PDF]

open access: yes, 2011
Microencapsulation of drugs into preformed polymers is commonly achieved through solvent evaporation techniques or spray drying. We compared these encapsulation methods in terms of controlled drug release properties of the prepared microparticles and ...
Donaldson, M   +4 more
core   +1 more source

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