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Drug-Drug Interactions: Antiretroviral Drugs and Recreational Drugs

Recent Patents on CNS Drug Discovery, 2015
With the advances in antiretroviral (ARV) therapy, patients with Human Immunodeficiency Virus (HIV) infection are living longer, however, some patients encounter co- morbidities which sometimes require treatment. Therefore, during the treatment with ARV drugs these patients could take several recreational drugs (e.g.
Antonio Siniscalchi   +6 more
openaire   +3 more sources

Therapeutic Drug Monitoring and Drug–Drug Interactions Involving Antiretroviral Drugs

Antiviral Therapy, 2005
The consensus of current international guidelines for the treatment of HIV infection is that data on therapeutic drug monitoring (TDM) of non-nucleoside reverse transcriptase inhibitors (NNRTIs) and protease inhibitors (PIs) provide a framework for the implementation of TDM in certain defined scenarios in clinical practice. However, the utility of TDM
Boffito, M   +11 more
openaire   +5 more sources

Monitoring of Drug-Drug and Drug-Food Interactions

American Journal of Health-System Pharmacy, 1988
A program for detecting and preventing potentially serious drug-drug and drug-food interactions is described. Two clinical pharmacists developed drug interaction alert (DIA) cards for each potential interaction to be monitored. The cards contain information about the proposed mechanism and potential result of the interaction, as well as information ...
Susan M. Garabedian-Ruffalo   +3 more
openaire   +3 more sources

Drug-drug and drug-disease interactions with nonsteroidal anti-inflammatory drugs

The American Journal of Medicine, 1986
Nonsteroidal anti-inflammatory drugs may cause a number of drug interactions. They can displace other drugs from serum proteins, and some can affect the metabolism or decrease the renal elimination of other drugs. In addition, they can attenuate the pharmacologic effect of other drugs, such as diuretic and antihypertensive agents, without affecting ...
John H. Greist   +3 more
openaire   +6 more sources

Drug delivery

Drug Discovery Today, 2001
Monitor provides an insight into the latest developments in drug discovery through brief synopses of recent presentations and publications together with expert commentaries on the latest technologies. There are two sections: Molecules summarizes the chemistry and the pharmacological significance and biological relevance of new molecules reported in the
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Drug–drug interaction with statins

Expert Review of Clinical Pharmacology, 2008
3-hydroxy-3-methyl-glutaryl (HMG)-CoA reductase inhibitors (the so-called statins: atorvastatin, fluvastatin, pravastatin, lovastatin, rosuvastatin and simvastatin) are a well-established class of drugs in the treatment of hypercholesterolemia. Statin monotherapy is generally well tolerated, with a low frequency of adverse events.
A. Corsini, S. Bellosta
openaire   +3 more sources

Drug Repurposing Based on Drug–Drug Interaction

Chemical Biology & Drug Design, 2014
Given the high risk and lengthy procedure of traditional drug development, drug repurposing is gaining more and more attention. Although many types of drug information have been used to repurpose drugs, drug–drug interaction data, which imply possible physiological effects or targets of drugs, remain unexploited.
Ping Wu   +3 more
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A drug-to-drug interaction package

Computer Methods and Programs in Biomedicine, 1989
This paper describes an electronic database for handling the interactions between active principles administered to various patients. The computer used is a personal computer with adequate mass memory, software, and data obtained from pharmacological sources.
PINCIROLI, FRANCESCO, POZZI, GIUSEPPE
openaire   +4 more sources

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