Results 321 to 330 of about 12,292,416 (404)

Key role for inhibins in effective T cell activation, migration and Th17 differentiation

FEBS Open Bio, EarlyView.
Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco, Roxana Olguín‐Alor, Lizbeth Bolaños‐Castro, Alexandra Morales‐Cruz, Marisol De La Fuente‐Granada, Gloria Soldevila   +5 more
wiley   +1 more source

Study of epinephrine-induced cardiovascular adverse events in patients with anaphylaxis using two spontaneously reported adverse event databases from 2004 to 2024. [PDF]

Sci Rep
Kamath P, Rao RR, Kamath A.
europepmc   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024

FEBS Open Bio, EarlyView.
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior, Michaela Kocholata, Marilena E. Lekka, Olga Janouskova, Moran Yadid, Maja Kosanovic   +5 more
wiley   +1 more source

Research on drug addiction detection based on AR-TSNET with bimodal EEG-NIRS. [PDF]

Biomed Eng Online
Zhang X, Gu X, Chen L, Cao X, Zhang C, Li X.   +5 more
europepmc   +1 more source

Intracavernous Drug Delivery System [PDF]

, 1990
Kulvelis, F., Popken, G., Sommerkamp, H., Staubesand, J., Stief, Christian Georg, Wetterauer, Ulrich   +5 more
core  

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

FEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu, Yumi Iwashita, Keisuke Tachibana, Itsuki Nishino, Yuki Niwa, Atsuko Uyeda, Kazuki Matsuo, Masahiro Nagahama, Masuo Kondoh   +8 more
wiley   +1 more source

"We knew it was coming: we didn't act" perspectives from people who use drugs and substance use workforce on the impact of delays in implementation of the supervised injection facility and drug checking interventions. [PDF]

Harm Reduct J
Hester MR, Hughto JMW, Ravikumar-Grant D, Nic Gabhainn S.   +3 more
europepmc   +1 more source

Lipid-based nanoparticles external triggered release strategies in cancer nanomedicine. [PDF]

J Nanobiotechnology
Alhussan A, Ho L, Zhang Y, Fan H, Momeni A, Brimacombe C, Cullis PR.   +6 more
europepmc   +1 more source

VCTatDot and VCTatMLP: novel deep learning models with triadic attention embeddings for synergistic drug combination prediction. [PDF]

Sci Rep
Majidifar S, Hooshmand M.
europepmc   +1 more source