Results 31 to 40 of about 8,662,910 (358)

Drug Management Reviews in District Drug Management Unit and General Hospital [PDF]

open access: yes, 2009
Drug is one of the essential elements in healthcare that should be effectively and efficiently managed. Following the decentralization in 2001 in Indonesia, drug management has changed in district drug management units and also in District General ...
Handayani, R. S. (Rini)   +2 more
core  

Synergistic drug combinations from electronic health records and gene expression. [PDF]

open access: yes, 2016
ObjectiveUsing electronic health records (EHRs) and biomolecular data, we sought to discover drug pairs with synergistic repurposing potential. EHRs provide real-world treatment and outcome patterns, while complementary biomolecular data, including ...
Chen, William   +19 more
core   +2 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Arrests for Drug Offenses in Alaska: 2000-2011 [PDF]

open access: yes, 2013
This fact sheet presents data on arrests for drug offenses made by Alaska police agencies for the period 2000 through 2011. The report presents drug offense arrest information for both adults and juveniles for the 12-year period, including number of drug
Myrstol, Brad A.
core  

The use of drug calendars for the diagnosis of cutaneous drug eruptions in the age of electronic medical records [PDF]

open access: yes, 2020
A morbilliform drug eruption is the most common condition leading to a dermatology consultation for a patient in the hospital. Timing is an important diagnostic tool since the onset of a skin rash usually takes place within days-to-weeks of the start of ...
Cohen, Philip R, Grossman, Marc E
core  

Customizing the therapeutic response of signaling networks to promote antitumor responses by drug combinations [PDF]

open access: yes, 2014
Drug resistance, de novo and acquired, pervades cellular signaling networks (SNs) from one signaling motif to another as a result of cancer progression and/or drug intervention.
Bown, James L.   +4 more
core   +5 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Drug Possession Arrests Reported in Alaska, 1986–2017 — Drug Types by Sex [PDF]

open access: yes, 2018
Underlying data is available in both Excel and PDF format. (Download below.)This fact sheet presents data on drug possession arrests by type of drug and sex of arrestee as reported by Alaska law enforcement agencies for the 32-year period 1986 to 2017 ...
Ervin, Benjamin
core  

‘Initiation into drug use’ addendum: findings from the DUMA program [PDF]

open access: yes, 2012
The age at which an individual first experiments with illicit drugs has been of significant interest to policymakers and practitioners, primarily because research has persistently shown a link between early juvenile onset of drug use and less favourable ...
Jason Payne, Josh Sweeney
core   +1 more source

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