Results 41 to 50 of about 6,956,165 (310)
Frontiers in Pharmacology, 2021 Traditional methods to standardize exposures in pharmacoepidemiologic studies, like defined daily-doses, may be inadequate to capture drug class effects when there are many in-class medications, formulations, and administration routes.
Kaleen N. Hayes +8 more
doaj +1 more source
Optimal loading of hydrogel-based drug-delivery systems [PDF]
arXiv, 2022 Drug-loaded hydrogels provide a means to deliver pharmaceutical agents to specific sites within the body at a controlled rate. The aim of this paper is to understand how controlled drug release can be achieved by tuning the initial distribution of drug molecules in a hydrogel. A mathematical model is presented for a spherical drug-loaded hydrogel.
arxiv
DRUG-NEM: Optimizing drug combinations using single-cell perturbation response to account for intratumoral heterogeneity. [PDF]
, 2018 An individual malignant tumor is composed of a heterogeneous collection of single cells with distinct molecular and phenotypic features, a phenomenon termed intratumoral heterogeneity.
Anchang, Benedict +8 more
core +1 more source
Jornal Brasileiro de Nefrologia, 2014 A doenca renal cronica (DRC), considerada a grande epidemia deste milenio, tem prevalencia media de 11% nos paises desenvolvidos. Infelizmente, no Brasil ainda nao dispomos de dados definitivos sobre a prevalencia da DRC, contudo, estudo realizado em amostra de 24.248 individuos adultos, utilizando o criterio de DRC baseado em duas determinacoes da ...
openaire +3 more sources
A clustering and graph deep learning-based framework for COVID-19 drug repurposing [PDF]
arXiv, 2023 Drug repurposing (or repositioning) is the process of finding new therapeutic uses for drugs already approved by drug regulatory authorities (e.g., the Food and Drug Administration (FDA) and Therapeutic Goods Administration (TGA)) for other diseases. This involves analyzing the interactions between different biological entities, such as drug targets ...
arxiv
Drug Possession Arrests Reported in Alaska, 1986–2017 [PDF]
, 2018 Underlying data is available in both Excel and PDF format. (Download below.)This fact sheet presents data on drug sale possession arrests reported by Alaska law enforcement agencies for the 32-year period 1986 to 2017. Overall, the drug possession arrest
Ervin, Benjamin
core
Adverse reactions of amiodarone [PDF]
, 2019 Adverse drug reaction is defined by the World Health Organization as any response to a drug that is noxious and unintended and occurs at a dose normally used in man.
Calvosa, Leonardo +5 more
core +1 more source
Frontiers in Psychiatry, 2022 Abuses of most illegal drugs, including methamphetamine, marijuana, cocaine, heroin, and polydrug, are usually in conjunction with alcohol and tobacco.
HuiLing Li +9 more
doaj +1 more source
Drug Possession Arrests Reported in Alaska, 1986–2017 — Drug Types by Sex [PDF]
, 2018 Underlying data is available in both Excel and PDF format. (Download below.)This fact sheet presents data on drug possession arrests by type of drug and sex of arrestee as reported by Alaska law enforcement agencies for the 32-year period 1986 to 2017 ...
Ervin, Benjamin
core
Local and global modes of drug action in biochemical networks [PDF]
, 2008 It becomes increasingly accepted that a shift is needed from the traditional target-based approach of drug development to an integrated perspective of drug action in biochemical systems. We here present an integrative analysis of the interactions between
A Ma'ayan +30 more
core +4 more sources