Results 61 to 70 of about 7,787,075 (304)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Beginning and development of the abuse and illegal traffic of drugs in Kosovo and Metohia [PDF]
Baština, 2013 Drug addiction (toxicomany) became a global social, psycho-medical, and political-legal problem of the 70-ies of the 20th century. At the end of the 20th and at the beginning of the 21st century this pandemy, white plague, is beginning an important ...
Beriša Hatidža
doaj
Polyelectrolyte multilayer assembly bearing ketoprofen for transdermal delivery [PDF]
, 2009 A novel microencapsulation technology based on layer-by-layer assembly has been extensively studied and used for controlled delivery of drug microcrystal having poor aqueous solubility and low bioavailability.
Preeti Yadav +2 more
core +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Immunosuppressive Therapy Protocols in Kidney Transplantation in Adults
Biomolecules & Biomedicine, 2006 In practical terms, regardless of HLA compatibility level, whenever tissues are transplanted from one person to another it is essential to suppress the immune response of the recipient.
Jasenko Karamehić +6 more
doaj +1 more source
The processes of reform in Victoria’s alcohol and other drug sector, 2011-2014 [PDF]
This paper explores issues and concerns related to the 2014 alcohol and other drug sector recommissioning process in Victoria. Overview In mid-2014, the Victorian Alcohol and Drug Association approached the Drug Policy Modelling Program, at the ...
Drug Policy Modelling Program
core
Consolidation and Innovation in the Pharmaceutical Industry: The Role of Mergers and Acquisitions in the Current Innovation Ecosystem [PDF]
, 2018 Recent changes in the pharmaceutical industry have spurred an unprecedented wave of mergers and acquisitions. Some researchers and agencies have questioned whether pharmaceutical consolidation could impede drug innovation.
Shepherd, Joanna
core +2 more sources
Antimicrobials in animal agriculture: Parables and policy [PDF]
, 2015 In addition to the scientific, economic, regulatory and other policy factors that impact on antimicrobial decision-making in different jurisdictions around the world, there exist ethical, social and cultural bases for the contemporary use of these ...
Aarestrup +43 more
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Drug Possession Arrests Reported in Alaska, 1986–2017 — Drug Types by Sex [PDF]
, 2018 Underlying data is available in both Excel and PDF format. (Download below.)This fact sheet presents data on drug possession arrests by type of drug and sex of arrestee as reported by Alaska law enforcement agencies for the 32-year period 1986 to 2017 ...
Ervin, Benjamin
core