Results 71 to 80 of about 7,787,075 (304)
Controlled release from zein matrices: Interplay of drug hydrophobicity and pH [PDF]
, 2015 Purpose: In earlier studies, the corn protein zein is found to be suitable as a sustained release agent, yet the range of drugs for which zein has been studied remains small.
A Katchalsky +34 more
core +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Frontiers in Pharmacology, 2020 The recent outbreak of the COVID-2019 (coronavirus disease 2019) due to the infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has realized the requirement of alternative therapeutics to mitigate and alleviate this lethal infection ...
Rajnish Kumar +11 more
doaj +1 more source
The impact of drug treatment courts on recovery: a systematic review [PDF]
, 2013 Introduction. Earlier reviews regarding the effectiveness of Drug Treatment Courts (DTCs) reported a reduction in reoffending and substance use. Although substance users suffer from other difficulties than drug use and judicial issues, none of these ...
De Ruyver, Brice +4 more
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Complexity in Pharmaceutical Powders for Inhalation: A perspective
KONA Powder and Particle Journal, 2017 Pharmaceutical aerosol powders intended for inhalation are required to have unique performance characteristics that are highly dependent on their physico-chemical properties.
Anthony J. Hickey
doaj +1 more source
Rozprawy Społeczne, 2020 In this study, I would like to draw the readers' attention to the size reached by the contemporary advertising market of medications, dietary supplements and medical devices.
Adam Zalewski
doaj +1 more source
Constructing Drug Using Victims: Race and Class in Policy Debates on Ecstasy Use in the U.S. [PDF]
, 2019 Sociologists and political scientists examining the social construction of public anxiety surrounding drug use in the United States have argued that racial minorities are the targets of the harshest drug laws, while middle-class whites are shielded.
Laguna, Sofia Isabel
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Arrests for Drug Offenses in Alaska: 2000–2011 [PDF]
, 2014 REVISION NOTE: Following the publication of the fact sheet — “Arrests for Drug Offenses in Alaska: 2000-2012” — the Alaska Justice Statistical Analysis Center (AJSAC) was informed by the Alaska Department of Public Safety (DPS) that the UCR drug arrest ...
Parker, Khristy
core