Drug Metabolism And Disposition, 2014 Adult intestinal stem cells (ISCs) possess both a long-term proliferation ability and differentiation capability into enterocytes. As a novel in vitro system for the evaluation of drug absorption, we characterized a human small intestinal epithelial cell
T. Takenaka +5 more
semanticscholar +1 more source
Photocatalytic degradation of ketorolac tromethamine (KTC) drug in aqueous phase using prepared Ag-doped ZnO microplates [PDF]
, 2017 In this study, Ag-doped ZnO microplates were prepared via precipitation technique and further characterized by FESEM, EDS, XRD, FTIR, TGA, XPS, UV-DRS and RT-PL techniques.
Ibhadon, Alex +2 more
core +1 more source
Interaction of an Antituberculosis Drug with a Nanoscopic Macromolecular Assembly: Temperature-Dependent Förster Resonance Energy Transfer Studies on Rifampicin in an Anionic Sodium Dodecyl Sulfate Micelle [PDF]
, 2011 In this contribution, we report studies on the nature of binding of a potent antituberculosis drug, Rifampicin (RF) with a model drug delivery system, sodium dodecyl sulfate (SDS) micelle.
Makhal, Abhinandan +3 more
core
Ex-vivo evaluation of crab shell chitosan as absorption enhancer in ciprofloxacin tablet formulation [PDF]
, 2016 This study was aimed at evaluating crab shell chitosan as absorption enhancer in ciprofloxacin tablet formulation using the ex-vivo model. Six batches of ciprofloxacin tablets containing varying concentrations of crab shell-derived chitosan ranging from ...
Etukudo, Unyime B. +3 more
core +2 more sources
The Influence of the Electric Current on the Absorption of Drugs [PDF]
, 1921 O. Inchley
openalex +1 more source
Role of gastrointestinal multidrug resistance (MDR1) gene and P-glycoprotein (P-gp) in the oral absorption of methadone in horses [PDF]
, 2010 Methadone is a mu-opioid receptor agonist which is a very effective analgesic used to treat moderate to severe acute and chronic pain in humans. Due to methadone’s minimal undesirable side-effects in people, we believed it could be of use in horses as an
Linardi, Renata Lehn
core +2 more sources
AAPS PharmSciTech, 2014 Typically, colonic absorption of a drug is mandatory for a sustained release formulation to hold the drug’s plasma level for more than 12 or 24 h above the minimum therapeutic plasma concentration (efficacy). According to Drugs@FDA, only 7.4% of the oral
D. Becker +6 more
semanticscholar +1 more source
How do antimalarial drugs reach their intracellular targets?
Frontiers in Pharmacology, 2015 Drugs represent the primary treatment available for human malaria, as caused by Plasmodium spp. Currently approved drugs and antimalarial drug leads generally work against parasite enzymes or activities within infected erythrocytes.
Katherine eBasore +4 more
doaj +1 more source
Pharmacometrics Modeling via Physics-Informed Neural Networks: Integrating Time-Variant Absorption Rates and Fractional Calculus for Enhancing Prediction Accuracy [PDF]
CMBE 2024 Proceedings Vol. 2We present a novel method to improve pharmacokinetics modeling, an essential step of drug development. Conventional models frequently fail to fully represent the intricacies of drug absorption and distribution, which limits their predictive abilities required for personalized treatment strategies.
arxiv
Self-depression of the Subcutaneous Absorption of Drugs due to Release of Histamine [PDF]
, 1958 Jens Schou
openalex +1 more source