Results 61 to 70 of about 5,685,542 (420)

Glycerol gelatin for 3D-printing of implants using a paste extrusion technique

open access: yesCurrent Directions in Biomedical Engineering, 2017
Fused deposition modeling as an additive manufacturing technique has gained great popularity for the fabrication of medical devices as well as pharmaceutical dosage forms over the last years.
Kempin Wiebke   +3 more
doaj   +1 more source

Partitioning and Spatial Distribution of Drugs in Ocular Surface Tissues

open access: yesPharmaceutics, 2021
Ocular drug absorption after eye drop instillation has been widely studied, but partitioning phenomena and spatial drug distribution are poorly understood.
Anusha Balla   +9 more
doaj   +1 more source

Molecular Communication for Quorum Sensing Inspired Cooperative Drug Delivery [PDF]

open access: yesarXiv, 2023
A cooperative drug delivery system is proposed, where quorum sensing (QS), a density-dependent bacterial behavior coordination mechanism, is employed by synthetic bacterium-based nanomachines (B-NMs) for controllable drug delivery. In our proposed system, drug delivery is only triggered when there are enough QS molecules, which in turn only happens ...
arxiv  

In Vitro Methods for Evaluating Drug Release of Vaginal Ring Formulations—A Critical Review

open access: yesPharmaceutics, 2019
The vagina is a promising site for both local and systemic drug delivery and represents an interesting administration route for compounds with poor oral bioavailability.
Katharina Tietz, Sandra Klein
doaj   +1 more source

Exploring the Effect of Esomeprazole on Gastric and Duodenal Fluid Volumes and Absorption of Ritonavir

open access: yesPharmaceutics, 2020
Proton-pump inhibitors (PPIs), frequently prescribed to lower gastric acid secretion, often exert an effect on the absorption of co-medicated drug products.
Tom de Waal   +7 more
doaj   +1 more source

Correlating Mass Spectrometry Imaging and Liquid Chromatography-Tandem Mass Spectrometry for Tissue-Based Pharmacokinetic Studies

open access: yesMetabolites, 2022
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is a standard tool used for absolute quantification of drugs in pharmacokinetic (PK) studies.
Andreas Dannhorn   +7 more
doaj   +1 more source

In vitro simulation of distribution processes following intramuscular injection

open access: yesCurrent Directions in Biomedical Engineering, 2016
There is an urgent need for in vitro dissolution test setups for intramuscularly applied dosage forms. Especially biorelevant methods are needed to predict the in vivo behavior of newly developed dosage forms in a realistic way.
Probst Mareike   +3 more
doaj   +1 more source

Portable Iontophoresis Device for Efficient Drug Delivery

open access: yesBioengineering, 2023
The timely delivery of drugs to specific locations in the body is imperative to ensure the efficacy of treatment. This study introduces a portable facial device that can deliver drugs efficiently using iontophoresis.
Moonjeong Bok   +3 more
doaj   +1 more source

Designing drug regimens that mitigate nonadherence [PDF]

open access: yesarXiv, 2021
Medication adherence is a well-known problem for pharmaceutical treatment of chronic diseases. Understanding how nonadherence affects treatment efficacy is made difficult by the ethics of clinical trials that force patients to skip doses of the medication being tested, the unpredictable timing of missed doses by actual patients, and the many competing ...
arxiv  

Development and Evaluation of Gastro-retentive Floating Tablet of Rilpivirine Hydrochloride for the Treatment of HIV [PDF]

open access: yes, 2020
Besides enormous improvements in drug delivery, oral route has been highly and effectively utilized route of administration. Floating drug delivery that is also known to be low density system is advancement in the class of gastro-retentive drug delivery ...
Majumdar, Arti   +2 more
core   +2 more sources

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