Results 251 to 260 of about 435,266 (312)

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Reply on "Why compulsive sexual behavior is not a form of addiction like drug addiction". [PDF]

Sex Med
Stark R, Walter B, Bengesser I, Kramer D, Muhl C, Tahmassebi N, Khatib S, Storz F, Markert C, Golder S.   +9 more
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Astrocytic transcriptional and epigenetic mechanisms of drug addiction. [PDF]

J Neural Transm (Vienna)
Holt LM, Nestler EJ.
europepmc   +1 more source

Usrah Approach of Drug Addiction Treatment in a Fishermen Community: Psychology of Da’wah Perspective

, 2019
Wan Hanis Aisyah Wan Rosdi, Zawawi Yusoff, Nasir Mohamad, Shafie Hamzah, S. Masaud   +4 more
openalex   +2 more sources

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Myoclonus Associated with Mirtazapine

Indian Journal of Psychological Medicine
Surabhi Sharma, Ravi Yadav, Dinesh Kataria   +2 more
doaj   +1 more source

Advances in Brain Stimulation, Nanomedicine and the Use of Magnetoelectric Nanoparticles: Dopaminergic Alterations and Their Role in Neurodegeneration and Drug Addiction. [PDF]

Molecules
Giménez S, Millan A, Mora-Morell A, Ayuso N, Gastaldo-Jordán I, Pardo M.   +5 more
europepmc   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Why compulsive sexual behavior is not a form of addiction like drug addiction. [PDF]

Sex Med
Hesse M.
europepmc   +1 more source