Virology Journal, 2019 Background Vaccination and the use of neuraminidase inhibitors (NAIs) are currently the front lines of defense against seasonal influenza. The activity of influenza vaccines and antivirals drugs such as the NAIs can be affected by mutations in the ...
Natalia A. Ilyushina +6 more
doaj +1 more source
An observational assessment of the safety of mass drug administration for trachoma in Ethiopian children [PDF]
, 2022 Allan Ciciriello +14 more
openalex +1 more source
A dog model for acetaminophen-induced fulminant hepatic failure. [PDF]
, 1989 The development of a large animal model of fulminant hepatic failure produced with acetaminophen that should be useful in the development and evaluation of potential medical therapies for the important clinical problem of fulminant hepatic failure is ...
Barone, M +7 more
core +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Dual functional POGases from bacteria encompassing broader O-glycanase and adhesin activities
Nature CommunicationsMucin-type O-glycans on glycoproteins are pivotal for biology and impact the quality of biotherapeutics. Furthermore, glycans on host cells serve as ligands for lectins/adhesins on bacteria for bacterium-host interactions in the colonization or ...
Linjiao Zhou +12 more
doaj +1 more source
Additively manufactured medical products – the FDA perspective
3D Printing in Medicine, 2016 Additive manufacturing/3D printing of medical devices is becoming more commonplace, a 3D printed drug is now commercially available, and bioprinting is poised to transition from laboratory to market.
Matthew Di Prima +5 more
doaj +1 more source
Increased Response Variability and Attentional Lapses After Chronic Cocaine Self-Administration [PDF]
, 2009 In humans, cocaine use has long been associated with poor attentional control and decreased efficiency in goal-oriented behavior. Animal models of these stereotypic drug effects, however, have thus far failed to produce quantifiable data sets in part ...
Olsen, Adam
core
Fair Hearing in Administrative Rule-Making: A Recent Experience Under the Federal Food, Drug, and Cosmetic and Fair Packaging and Labeling Acts [PDF]
, 1968 In promulgating regulations to govern the labeling of foods under the Fair Packaging and Labeling Act, the Commissioner of Food and Drugs, despite the objections of adversely affected parties, denied all requests for a public hearing. In this article the
Forte, Wesley E.
core +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Severe Type of Erythema Multiforme (EM major) due to Administration of Anti-PD-1 Antibody Drug
, 2021 Shoya Yano, Aika Okuno, Fukumi Furukawa
openalex +2 more sources