Results 121 to 130 of about 7,897,516 (385)

Evaluation of Medication Error Reports Sent to Food and Drug Deputy From Hospitals Affiliated to Mazandaran University of Medical Sciences, Mazandaran Province, Iran, 2015-2018

Pharmaceutical and Biomedical Research, 2020
Background: Medical errors are one of the most common threats to patient safety. Medication errors have several consequences, including the increase in patients’ mortality, length of stay, and healthcare costs.
Mohammad Eslami Jouybari, Fatemeh Izadpanah, Mina Amini   +2 more
doaj   +1 more source

Intracerebroventricular drug administration

Translational and Clinical Pharmacology, 2017
Among the various routes of drug administration, perhaps the least studied is intracerebroventricular (ICV) administration. This route has been shown to be particularly useful in administering to the central nervous system (CNS) drugs that do not cross ...
A. Atkinson
semanticscholar   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Extracting adverse drug reactions and their context using sequence labelling ensembles in TAC2017

, 2018
Adverse drug reactions (ADRs) are unwanted or harmful effects experienced after the administration of a certain drug or a combination of drugs, presenting a challenge for drug development and drug administration.
Belousov, Maksim, Dixon, William, Milosevic, Nikola, Nenadic, Goran   +3 more
core  

Reporting bias in drug trials submitted to the Food and Drug Administration: review of publication and presentation. [PDF]

, 2008
BackgroundPrevious studies of drug trials submitted to regulatory authorities have documented selective reporting of both entire trials and favorable results.
Bacchetti, Peter, Bero, Lisa, Rising, Kristin   +2 more
core   +3 more sources

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

SIAIP position paper: provocation challenge to antibiotics and non-steroidal anti-inflammatory drugs in children [PDF]

, 2018
Drug hypersensitivity reactions (DHRs) in childhood are mainly caused by betalactam or non-betalactam antibiotics, and non-steroidal anti-inflammatory drugs (NSAIDs).
Arasi, Stefania, Barni, Simona, Bottau, Paolo, Caffarelli, Carlo, Caimmi, Davide, Caimmi, Silvia, Cardinale, Fabio, Comberiati, Pasquale, Crisafulli, SEBASTIANO GIUSEPPE, Di Mauro, Dora, Diaferio, Lucia, Duse, Marzia, Franceschini, Fabrizio, Liotti, Lucia, Marseglia, Gianluigi, Mastrorilli, Carla, Mori, Francesca, Paravati, Francesco, Pelosi, Umberto, Saretta, Francesca   +19 more
core   +1 more source

Injection-Site Nodules Associated With the Use of Exenatide Extended-Release Reported to the U.S. Food and Drug Administration Adverse Event Reporting System

Diabetes Spectrum, 2015
Glucagon-like peptide-1 (GLP-1) receptor agonists are safe and effective U.S. Food and Drug Administration (FDA)-approved drug products for use in the treatment of type 2 diabetes.
S. Jones, Debra L. Ryan, Valerie Pratt, A. Niak, A. Brinker   +4 more
semanticscholar   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Deadly in Pink: Big Tobacco Steps Up Its Targeting of Women and Girls [PDF]

, 2009
Outlines the tobacco industry's marketing campaigns targeting women and girls, with examples of advertisements and the effects on women's health.

core