Results 161 to 170 of about 9,077,301 (404)

Cost of Mass Drug Administration for Filariasis Elimination in the province of Sorsogon, Philippines

, 2023
Maria Lourdes E. Amarillo, Vicente Y. Belizario, Carlo Irwin A. Panelo, Stephanie Anne M. Sison, Winifreda U. de Leon, Bernadette Ramirez, Leah P. Adrid   +6 more
openalex   +2 more sources

POS0644 UNDERSTANDING REASONS INFLUENCING PATIENTS’ PREFERENCES FOR THE MODE OF ADMINISTRATION OF ANTI-RHEUMATIC DRUGS IN INFLAMMATORY ARTHRITIS. A QUALITATIVE STUDY [PDF]

, 2023
Catherine Beauvais, G. Montagu, Francesco Madrisotti, S. Gleizes, Sonia Tropé, Jérémie Sellam, Thao Pham   +6 more
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Successes and challenges of PARP inhibitors in cancer therapy

Frontiers in Oncology, 2015
Tiffany K Ricks, Haw-Jyh eChiu, Gwynn eIson, Geoffrey eKim, Amy E McKee, Paul eKluetz, Richard ePazdur   +6 more
doaj   +1 more source

An Empirical Argument for Nontechnical Public Members on Advisory Committees: FDA As a Model [PDF]

, 1990
A discussion of the results of two surveys of present and past members of Food and Drug Administration Advisory Committees. The views and understanding of the issues before various categories of membership are compared and contrasted.
Lakshmanan, Joseph L.
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Cardiac Adverse Events in Patients Receiving Immune Checkpoint Inhibitors in the Adjuvant Setting: An FDA Pooled Analysis

Annals of Noninvasive Electrocardiology
Background Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment. By releasing blocks (checkpoints) on the immune system, they elicit powerful antitumor effects.
Asma Dilawari, Mori J. Krantz, Ilynn Bulatao, Hee‐Koung Joeng, Marc Neilson, Suparna Wedam, Xin Gao, Mallorie H. Fiero, Abhilasha Nair, Marc Theoret, Laleh Amiri‐Kordestani   +10 more
doaj   +1 more source

National Comprehensive Trachoma Treatment Campaign: Community Monitoring of Mass Drug Administration (MDA) Coverage and Practices

, 2022
Hassan Abdulwahab Al-Shamahy
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Novel protocol for multiple-dose oral administration of the L-type Ca2+ channel blocker isradipine in mice: A dose-finding pharmacokinetic study

Channels
Studies in genetically modified animals and human genetics have recently provided new insight into the role of voltage-gated L-type Ca2+ channels in human disease.
Tamara Theiner, Nadine J. Ortner, Herbert Oberacher, Gospava Stojanovic, Petronel Tuluc, Jörg Striessnig   +5 more
doaj   +1 more source