Results 181 to 190 of about 9,077,301 (404)

Intraperitoneal Route of Drug Administration: Should it Be Used in Experimental Animal Studies?

Pharmaceutical Research, 2019
Abdullah Al Shoyaib, Sabrina Rahman Archie, V. Karamyan   +2 more
semanticscholar   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Polymeric Drugs and Drug Administration [PDF]

, 1994
Polymer systems for biomedical applications - an overview, Raphael M. Ottenbrite and Natalya Fadeeva bioelastic materials and the dTt-mechanisms in drug delivery, Dan W. Urry et al sequence-selective binding of DNA by oligopeptides as a novel approach to drug design, Moses Lee and Clint Walker protein device for glucose-sensitive release of insulin, Y.
openaire   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Successfully Navigating Food and Drug Administration Orphan Drug and Rare Pediatric Disease Designations for AAV9-hPCCA Gene Therapy: The National Institutes of Health Platform Vector Gene Therapy Experience

, 2023
Richa Madan Lomash, Oleg A. Shchelochkov, Randy J. Chandler, NIH PaVe-GT Team, Charles P. Venditti, Anne Pariser, Elizabeth A. Ottinger, Averion Gilberto V., Balakrishnan Krishna, Bönnemann Carsten G., Brooks Philip J., Burden Steven J., Campbell Eggerton, Chen Catherine, Choi Eun-Young, Driscoll Claire, Dukhanina Oksana, Ferry Susan, Foley A. Reghan, Hauserman Janelle Geist, Lina Li, Lo C, Mangalampalli Venkata, Manoli Irini, Mendoza Christopher, Oury Julien, Patel Kinjal D, Portero Deanna, Portilla Lili, Rooney Jachinta, Saade Dimah, Sloan Jennifer L., Tambe Mitali, Terse Pramod, Todd Joshua, Toney London, Van Ryzin Carol, Stan Rodica, Vepa Sury, Wagner Erik, Wang Amy, Xin Xu, Zou Yaqun   +42 more
openalex   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Study design considerations to assess the impact of potential drug–drug interactions in first‐in‐human studies in oncology drug development

Clinical and Translational Science, 2023
Sriram Subramaniam, Stacy S. Shord, Ruby Leong, Kelly Norsworthy, Atiqur Rahman, Brian Booth, Olanrewaju Okusanya   +6 more
doaj   +1 more source

Usefulness of the Final Filter of the IV Infusion Set in Intravenous Administration of Drugs-Contamination of Injection Preparations by Insoluble Microparticles and Its Causes-

, 2006
Keiji Kuramoto, Toru Shoji, Yoshito Nakagawa   +2 more
openalex   +2 more sources

Severe Type of Erythema Multiforme (EM major) due to Administration of Anti-PD-1 Antibody Drug

, 2021
Shoya Yano, Aika Okuno, Fukumi Furukawa
openalex   +2 more sources

Mass drug administration campaigns: Comparing two approaches for schistosomiasis and soil-transmitted helminths prevention and control in selected southern Malawi districts [PDF]

, 2022
Peter Makaula, Sekeleghe A. Kayuni, Kondwani Chidzammbuyo Mamba, Grace Bongololo, Mathias Funsanani, Lazarus Juziwelo, Janelisa Musaya, Peter Furu   +7 more
openalex   +1 more source