Results 211 to 220 of about 2,902,189 (362)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Feasibility and acceptability of integrating mass distribution of azithromycin to children 1–11 months into a trachoma mass drug administration campaign to reduce child mortality in Côte d’Ivoire

Lisa Dulli, Fatoumata Touré, Adam Djima Mama, Emily Evens, Kate Murray, N. Djé, Stéphane Koné, Pat Sadate-Ngatchou, Anoma Bovary, Marga Eichleay, Milenka Jean‐Baptiste, Aboulaye Meïté   +11 more
openalex   +1 more source

A Case of Severe Drug-Induced Hepatic Failure Caused by Continued Administration of Uracil/Tegafur (UFT) Capsules by Self-Judgement

, 2006
NORIAKI KITADA
openalex   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Evaluating a quality improvement intervention for schistosomiasis mass drug administration in Ghana using the RE-AIM framework. [PDF]

Epidemiol Infect
Vernot-Jonas N, Manyeh AK.
europepmc   +1 more source

Preparation of Polyglycolic Acid Gels for Oral Administration and Their Drug Releasing Behavior

, 2018
Kenta HATAGUCHI, Masaki Takahashi, Katsuki YAMORI, Michinori Karikomi, Takao Kimura, Fuminori Kobayashi, Yoshinori Suzuki   +6 more
openalex   +2 more sources

Food and Drug Administration [PDF]

BMJ, 2007
openaire   +2 more sources

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Design and Applications of Polymersomes for Oral Drug Administration. [PDF]

ACS Appl Mater Interfaces
Lai WF.
europepmc   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source