Results 221 to 230 of about 7,897,516 (385)

A general equation for the ratio of the areas below the blood or plasma concentration time‐curves following intravenous and oral drug administration and its application to inter‐subject variations in drug elimination. [PDF]

, 1975
DP Vaughan, A. Trainor
openalex   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Drug administration and food. [PDF]

, 1979
Campbell MacArthur
openalex   +1 more source

Design and Applications of Polymersomes for Oral Drug Administration. [PDF]

ACS Appl Mater Interfaces
Lai WF.
europepmc   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

EFFECT OF MORPHINE ADMINISTRATION ON THE ACTIVITIES OF MICROSOMAL DRUG-METABOLIZING ENZYME SYSTEMS IN LIVER OF DIFFERENT SPECIES

, 1966
Ryuichi Kato, Kin-ichi ONODA
openalex   +1 more source

Drug Administration Before or After Exposure to Low Temperatures-Does It Matter for the Therapeutic Effect? [PDF]

Int J Mol Sci
Bezirci K, Borisova B, Papadakis K, Danalev D, Nocheva H.   +4 more
europepmc   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Risk of Clinically Relevant Pharmacokinetic-Based Drug-Drug Interactions with Drugs Approved by the U.S. Food and Drug Administration Between 2013 and 2016

Drug Metabolism And Disposition, 2018
Jingjing Yu, Zhu Zhou, Jessica Tay-Sontheimer, R. Levy, I. Ragueneau-Majlessi   +4 more
semanticscholar   +1 more source

An integrated mass drug administration against hymenolepiasis and schistosomiasis in Sudan. [PDF]

Parasites Hosts Dis
Jin Y.
europepmc   +1 more source