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No licensed human vaccines are currently available against any parasitic disease including leishmaniasis. Several anti-leishmanial vaccine formulations have been tested in various animal models including genetically modified live attenuated parasite ...
Sreenivas eGannavaram +5 more
doaj +1 more source
Rate-controlled rectal drug delivery in man with a hydrogel preparation [PDF]
Cylindrical hydrogels of hydroxyethyl methacrylate (HEMA) and ethylene glycol dimethacrylate (EGDMA) as crosslinking agent were prepared by radical polymerization at 70°C.
Boer, A.G. de +4 more
core +3 more sources
Intranasal Administration of Drugs [PDF]
To investigate how nasally applied substances distribute in the nose depending on the form of application.Observer-blinded study.University hospital research unit.Fifteen healthy volunteers aged 22 to 32 years.Forms of application included (1) nasal drops applied with a pipette, (2) nasal spray, and (3) a system producing squirts.
Mandy, Scheibe +3 more
openaire +2 more sources
Cronobacter species cause infections in all age groups; however neonates are at highest risk and remain the most susceptible age group for life-threatening invasive disease. The genus contains seven species: C. sakazakii, C. malonaticus, C. turicensis C.
Ben Davies Tall +22 more
doaj +1 more source
This retrospective observational study evaluated racial disparities among Black and White patients with multiple myeloma (MM). We included patients from a longitudinal de-identified EHR-derived database who had ≥2 visits recorded on or after 1/1/2011 ...
Kathleen Maignan +10 more
doaj +1 more source
Inhaled Insulin: Intrapulmonary or Intranasal? [PDF]
Initial attempts delivered the insulin hormone intramuscularly, intravenously, and eventually subcutaneously. Other routes of administration of the drug were explored.
Danish Ahmed +3 more
core +2 more sources
Drugs and Drug Administration in Extreme Environments [PDF]
Emergency medicine must often cope with harsh climates far below freezing point or high temperatures, and sometimes, an alternative to the normal route of drug administration is necessary. Most of this information is not yet published. Therefore, we summarized the information about these topics for most drugs used in medical emergencies by combining ...
Thomas E A H, Küpper +5 more
openaire +2 more sources
The Coronavirus disease 2019 (COVID-19) pandemic has led to a surge in need for alternative routes of administration of drugs for end of life and palliative care, particularly in community settings.
J. Lam +6 more
semanticscholar +1 more source
Effectiveness of Self-instructional Modules on Knowledge Regarding Side-effects of Self-medication among Adolescents [PDF]
Introduction: Self-medication is an old practice and may be defined as drug acquisition and consumption without physician’s advice either for diagnosis, prescription, or treatment monitoring.
Archana T Maurya +5 more
doaj +1 more source
Intravenous versus subcutaneous drug administration. Which do patients prefer? A systematic review [PDF]
BACKGROUND: Intravenous (IV) drug delivery is commonly used for its rapid administration and immediate drug effect. Most studies compare IV to subcutaneous (SC) delivery in terms of safety and efficacy, but little is known about what patients prefer.
Fallowfield, Lesley J +3 more
core +1 more source

