BMC Veterinary Research, 2021 Status epilepticus (SE) or prolonged epileptic seizure activity is a common neurological emergency with a high mortality rate and, if left untreated, can lead to irreversible cerebral damage and systemic complications.
Marios Charalambous +3 more
doaj +2 more sources
Patterns of Routes of Administration and Drug Tampering for Nonmedical Opioid Consumption: Data Mining and Content Analysis of Reddit Discussions [PDF]
Journal of Medical Internet Research, 2021 BackgroundThe complex unfolding of the US opioid epidemic in the last 20 years has been the subject of a large body of medical and pharmacological research, and it has sparked a multidisciplinary discussion on how to implement interventions and policies ...
Balsamo, Duilio +3 more
doaj +2 more sources
Alternative Routes of Administration for Therapeutic Antibodies—State of the Art
Antibodies, 2022 Background: For the past two decades, there has been a huge expansion in the development of therapeutic antibodies, with 6 to 10 novel entities approved each year.
Aubin Pitiot +2 more
doaj +2 more sources
Drug Administration Routes Impact the Metabolism of a Synthetic Cannabinoid in the Zebrafish Larvae Model. [PDF]
Molecules, 2020 Zebrafish (Danio rerio) larvae have gained attention as a valid model to study in vivo drug metabolism and to predict human metabolism. The microinjection of compounds, oligonucleotides, or pathogens into zebrafish embryos at an early developmental stage
Park YM +3 more
europepmc +2 more sources
Extracellular Vesicles as Drug Carriers for Enzyme Replacement Therapy to Treat CLN2 Batten Disease: Optimization of Drug Administration Routes. [PDF]
Cells, 2020 CLN2 Batten disease (BD) is one of a broad class of lysosomal storage disorders that is characterized by the deficiency of lysosomal enzyme, TPP1, resulting in a build-up of toxic intracellular storage material in all organs and subsequent damage.
Haney MJ, Zhao Y, Jin YS, Batrakova EV.
europepmc +2 more sources
Drug delivery to the brain via the nasal route of administration: exploration of key targets and major consideration factors [PDF]
Journal of Pharmaceutical Investigation, 2022 Background Cranial nerve-related diseases such as brain tumors, Alzheimer’s disease, and epilepsy are serious diseases that continue to threaten human. Brain-related diseases are increasing worldwide, including in the United States and Korea, and these ...
Seung‐Hyun Jeong +2 more
openalex +2 more sources
Intranasal Drug Administration — An Attractive Delivery Route for Some Drugs
, 2015 Degenhard Marx +2 more
openalex +5 more sources
Tranexamic acid in melasma: A focused review on drug administration routes
Journal of Cosmetic Dermatology, 2023 Melasma is a disorder of hyperpigmentation and vascularization often found in women between the ages of 20 and 40. The pathogenesis is unknown, but melasma often occurs in sun‐exposed areas of the face, forearms, and back.
Hailey Konisky +4 more
semanticscholar +1 more source
Review of Clay-Drug Hybrid Materials for Biomedical Applications: Administration Routes [PDF]
Clays and clay minerals, 2016 Focus here is placed on the pharmaceutical and biomedical applications of novel clay-drug hybrid materials categorized by methods of administration. Clay minerals have been used for many years as pharmaceutical and medicinal ingredients for therapeutic ...
Myung Hun Kim +5 more
openalex +2 more sources
Formulation Strategies of Nanosuspensions for Various Administration Routes
Pharmaceutics, 2023 Nanosuspensions (NSs), which are nanosized colloidal particle systems, have recently become one of the most interesting substances in nanopharmaceuticals.
Sıla Gülbağ Pınar +3 more
semanticscholar +1 more source