Results 11 to 20 of about 286,603 (310)

Nanoparticles in the treatment of chronic lung diseases [PDF]

open access: yes, 2019
Nanoparticles, although considered a topic of modern medicine, actually have an interesting history. Currently, advances in nanomedicine hold great promise as drug carrier systems for sustained release and targeted delivery of diverse therapeutic agents.
Alexescu, Teodora G   +9 more
core   +2 more sources

Controlled-release of opioids for improved pain management [PDF]

open access: yes, 2016
The adequate treatment of pain remains one of the major medical challenges. Morphine and other opioid drugs are most commonly used to counteract moderate to severe pain, but they are also increasingly accessed by patients with chronic non-malignant pain.
Ballet, Steven   +5 more
core   +1 more source

Polysaccharide based formulations for mucosal drug delivery: A review [PDF]

open access: yes, 2015
There has been increased interest in novel drug delivery systems to be administered via mucosal routes as an alternative to the currently used traditional routes such as parenteral (injections) and oral routes of administration.
Boateng, Joshua   +2 more
core   +1 more source

Patterns of cocaine and opioid co-use and polyroutes of administration among street-based cocaine users in Montréal, Canada [PDF]

open access: yes, 2013
Background: Effective public health programs aimed at problematic cocaine users are challenged by the fact that they can have complex patterns of drug use with respect to polysubstance use and routes of drug administration.
Richer, Isabelle   +2 more
core   +1 more source

Drug Delivery to the Posterior Segment of the Eye: Biopharmaceutic and Pharmacokinetic Considerations

open access: yesPharmaceutics, 2020
The treatment of the posterior-segment ocular diseases, such as age-related eye diseases (AMD) or diabetic retinopathy (DR), present a challenge for ophthalmologists due to the complex anatomy and physiology of the eye. This specialized organ is composed
Rubén Varela-Fernández   +7 more
doaj   +1 more source

Intravenous versus subcutaneous drug administration. Which do patients prefer? A systematic review [PDF]

open access: yes, 2014
BACKGROUND: Intravenous (IV) drug delivery is commonly used for its rapid administration and immediate drug effect. Most studies compare IV to subcutaneous (SC) delivery in terms of safety and efficacy, but little is known about what patients prefer.
Fallowfield, Lesley J   +3 more
core   +1 more source

Drug Bioavailability Enhancing Agents of Natural Origin (Bioenhancers) that Modulate Drug Membrane Permeation and Pre-Systemic Metabolism

open access: yesPharmaceutics, 2019
Many new chemical entities are discovered with high therapeutic potential, however, many of these compounds exhibit unfavorable pharmacokinetic properties due to poor solubility and/or poor membrane permeation characteristics. The latter is mainly due to
Bianca Peterson   +5 more
doaj   +1 more source

Antibody Conjugation and Formulation [PDF]

open access: yes, 2019
In an era where ultra-high antibody concentrations, high viscosities, low volumes, auto-injectors, and long storage requirements are already complex problems with the current unconjugated monoclonal antibodies on the market the formulation demands for ...
Alves, Nathan J.
core   +1 more source

Contribution of Particle Design Research to the Development of Patient-Centric Dosage Forms

open access: yesKONA Powder and Particle Journal, 2021
A variety of dosage forms have been developed in order to achieve effective and safe drug delivery in topical or systemic drug administrations. In this review, formulation research and process issues related to a popular oral dosage form, the tablet, are
Hirofumi Takeuchi
doaj   +1 more source

Pharmaceutical assistance in the enteral administration of drugs: choosing the appropriate pharmaceutical formulation [PDF]

open access: yesEinstein (São Paulo), 2009
Objective: To study solid medications for oral delivery on the formulary of Hospital Israelita Albert Einstein (HIAE), investigating the  possibility of using these drugs through enteral feeding tubes, and recommending appropriate administration. Methods:
Gisele de Lima   +1 more
doaj  

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