Results 11 to 20 of about 286,603 (310)
Nanoparticles in the treatment of chronic lung diseases [PDF]
Nanoparticles, although considered a topic of modern medicine, actually have an interesting history. Currently, advances in nanomedicine hold great promise as drug carrier systems for sustained release and targeted delivery of diverse therapeutic agents.
Alexescu, Teodora G +9 more
core +2 more sources
Controlled-release of opioids for improved pain management [PDF]
The adequate treatment of pain remains one of the major medical challenges. Morphine and other opioid drugs are most commonly used to counteract moderate to severe pain, but they are also increasingly accessed by patients with chronic non-malignant pain.
Ballet, Steven +5 more
core +1 more source
Polysaccharide based formulations for mucosal drug delivery: A review [PDF]
There has been increased interest in novel drug delivery systems to be administered via mucosal routes as an alternative to the currently used traditional routes such as parenteral (injections) and oral routes of administration.
Boateng, Joshua +2 more
core +1 more source
Patterns of cocaine and opioid co-use and polyroutes of administration among street-based cocaine users in Montréal, Canada [PDF]
Background: Effective public health programs aimed at problematic cocaine users are challenged by the fact that they can have complex patterns of drug use with respect to polysubstance use and routes of drug administration.
Richer, Isabelle +2 more
core +1 more source
The treatment of the posterior-segment ocular diseases, such as age-related eye diseases (AMD) or diabetic retinopathy (DR), present a challenge for ophthalmologists due to the complex anatomy and physiology of the eye. This specialized organ is composed
Rubén Varela-Fernández +7 more
doaj +1 more source
Intravenous versus subcutaneous drug administration. Which do patients prefer? A systematic review [PDF]
BACKGROUND: Intravenous (IV) drug delivery is commonly used for its rapid administration and immediate drug effect. Most studies compare IV to subcutaneous (SC) delivery in terms of safety and efficacy, but little is known about what patients prefer.
Fallowfield, Lesley J +3 more
core +1 more source
Many new chemical entities are discovered with high therapeutic potential, however, many of these compounds exhibit unfavorable pharmacokinetic properties due to poor solubility and/or poor membrane permeation characteristics. The latter is mainly due to
Bianca Peterson +5 more
doaj +1 more source
Antibody Conjugation and Formulation [PDF]
In an era where ultra-high antibody concentrations, high viscosities, low volumes, auto-injectors, and long storage requirements are already complex problems with the current unconjugated monoclonal antibodies on the market the formulation demands for ...
Alves, Nathan J.
core +1 more source
Contribution of Particle Design Research to the Development of Patient-Centric Dosage Forms
A variety of dosage forms have been developed in order to achieve effective and safe drug delivery in topical or systemic drug administrations. In this review, formulation research and process issues related to a popular oral dosage form, the tablet, are
Hirofumi Takeuchi
doaj +1 more source
Pharmaceutical assistance in the enteral administration of drugs: choosing the appropriate pharmaceutical formulation [PDF]
Objective: To study solid medications for oral delivery on the formulary of Hospital Israelita Albert Einstein (HIAE), investigating the possibility of using these drugs through enteral feeding tubes, and recommending appropriate administration. Methods:
Gisele de Lima +1 more
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