Results 201 to 210 of about 286,603 (310)

New Insights into Drug Development via the Nose-to-Brain Pathway: Exemplification Through Dodecyl Creatine Ester for Neuronal Disorders. [PDF]

Pharmaceutics
Benech H, Flament V, Lhotellier C, Roucairol C, Joudinaud T.   +4 more
europepmc   +1 more source

From RNA to DNA: How Cargo Identity Reprograms Lipid Nanoparticle Architecture and Function

Advanced Healthcare Materials, EarlyView.
The evolution of lipid nanoparticles (LNPs) spans from RNA‐LNPs, used in mRNA vaccines, to DNA‐LNPs, ideal for gene therapies. Emerging bionano architectures, decorated with DNA and plasma proteins, pave the way for advanced DNA‐based therapies that are more stable, targeted, and customizable.
Erica Quagliarini, Daniela Pozzi, Giulio Caracciolo   +2 more
wiley   +1 more source

Validated RP-HPLC-UV Method for the Quantification of Trans-Resveratrol in Plasma: Application to Comprehensive Stability and Comparative Pharmacokinetic Studies. [PDF]

ACS Omega
Marwa A, Jufri M, Restu WK, Mohd Hashim NB, Bahtiar A.   +4 more
europepmc   +1 more source

Injectable Stimuli‐Responsive Amphiphilic Hydrogel for Rapid Hemostasis, Robust Tissue Adhesion, and Controlled Drug Delivery in Trauma and Surgical Care

Advanced Healthcare Materials, EarlyView.
Fast‐acting hydrogel seals bleeding wounds as the illustrated injectable, pH‐responsive network rapidly gels in situ to stop hemorrhage, adhere strongly to wet tissue, and release antibiotics in a controlled, pH‐dependent manner. The material withstands high pressures, shows excellent biocompatibility, and degrades safely, offering a versatile platform
Arvind K. Singh Chandel, Runali Patil, Abrar Ali Khan, Deeksha Pandit, Kaushik Chatterjee, Maurice N. Collins   +5 more
wiley   +1 more source

Does the Injection Site Matter During CPR? A Systematic Review and Meta-Analysis of Drug Pharmacokinetics and Pharmacodynamics. [PDF]

J Clin Med
Zagalioti SC, Gkarmiri S, Karagiannidis E, Stachteas P, Zgouridou A, Zagaliotis P, Kotzampassi K, Grosomanidis V, Raikos N, Aggou M, Fragakis N, Fyntanidou B.   +11 more
europepmc   +1 more source

Molecular Design of Highly Efficient Heavy‐Atom‐Free Near‐Infrared Cyanine Photosensitizers for Fluorescence Image‐Guided Photodynamic Therapy of Solid Tumors

Advanced Healthcare Materials, EarlyView.
Highly efficient heavy‐atom‐free NIR photosensitizers based on a heptamethine cyanine platform were developed for image‐guided photodynamic therapy. Both in vitro and in vivo results revealed that the R820‐3 photosensitizer with a highly twisted molecular structure exhibited potential for NIR fluorescence image‐guided photodynamic cancer therapy ...
Van‐Nghia Nguyen, Huixian Liang, Hyunsun Jeong, Jieun Bang, Chang Woo Koh, Kunemadihali Mathada Kotraiah Swamy, Sungnam Park, JaeHong Park, Fabiao Yu, Juyoung Yoon   +9 more
wiley   +1 more source

Development of a Physiologically Based Pharmacokinetic (PBPK) Simulation Model for Nicotine. [PDF]

Biopharm Drug Dispos
Kim B, Bae SH, Bashar M, Yi B, Rahman MA, Awuah P, Hartog M, Panarsky R, Zhang T.   +8 more
europepmc   +1 more source

Treatment of iron deficiency anemia: practical considerations [PDF]

, 2015
Rampton, D, Taylor, S
core   +1 more source

Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient‐Derived Model

Advanced Healthcare Materials, EarlyView.
This study shows that stem‐like cells isolated from breast cancer brain metastases drive the spread and growth of tumors in the brain. Among them, a highly adhesive subgroup initiates metastasis and resists many drugs. By closely reflecting patient tumors, these models help identify new targets and improve the development of effective treatments ...
Stefania Faletti, Cristina Richichi, Daniela Osti, Elena Ceccacci, Giovanni Bertalot, Camilla Cerutti, Giuseppina Giardina, Adriana Marinaro, Brunella Costanza, Valentina Gambino, Elena Zaccheroni, Daniela Tosoni, Maria G. Filippone, Marcello Del Corvo, Yinxiu Zhan, Teresa Gravina, Davide Corà, Monica Patanè, Bianca Pollo, Maria Giovanna Jodice, Salvatore Pece, Babette B. Weksler, Ignacio A. Romero, Pierre‐Olivier Couraud, Elisabetta Munzone, Massimiliano Del Bene, Francesco DiMeco, Giuliana Pelicci   +27 more
wiley   +1 more source

Patterns of drug prescription among hospitalized patients in a tertiary women's hospital: A retrospective drug utilization study. [PDF]

J Int Med Res
Omidifar N, Mahi-Birjand M, Askari P, Abolzadeh Oskuie P, Karimzadeh I, Mirjalili M, Hoorang M, Peymani P.   +7 more
europepmc   +1 more source