Results 201 to 210 of about 577,363 (331)

Evidence from a mouse model supports repurposing an anti-asthmatic drug, bambuterol, against Alzheimer’s disease by administration through an intranasal route

Anne‐Claire Groo, Thomas Curel, Aurélie Malzert‐Fréon, Line Séguy, Ophélie Bento, Sophie Corvaisier, Thomas Culerier, Romain Legrand, Noëlle Callizot, Alexandre Henriques, Georgia Culley, Sylvie Claeysen, Christophe Rochais, Patrick Dallemagne   +13 more
openalex   +1 more source

Methotrexate‐Loaded Liposomal Formulation Enables 6‐Week Sustained Intraocular Therapeutic Drug Release in a Porcine Model

Advanced Healthcare Materials, EarlyView.
A liposomal formulation for methotrexate enables minimally invasive, sustained intraocular drug delivery for over six weeks with a single injection. Developed for treating intraocular diseases like lymphoma and PVR, it offers excellent biocompatibility in vivo in a porcine model.
Maximilian Hammer, Lea Skrzypczyk, Sabrina Wohlfart, Bryan Calder Ackermann, Ludwig Geisweid, Simon William Pohl, Margarita Karaivanova, Jonathan Herth, Victor Aristide Augustin, Alexander Studier‐Fischer, Tina Sackmann, Leon Kaulen, Anna Steyer, Walter Mier, David H Steel, Kanmin Xue, Gerd Uwe Auffarth, Philipp Uhl   +17 more
wiley   +1 more source

Sublingual dexmedetomidine: An old drug with a new route for agitation. [PDF]

Saudi J Anaesth
Chittoria K, Sharma A, Kothari N, Goyal S.   +3 more
europepmc   +1 more source

Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration

Advanced Healthcare Materials, EarlyView.
This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli, Deepak Gupta, Yogendra Pratap Singh, Pallab Datta, Muhammad Rizwan, Mehmet Baykara, Ibrahim T. Ozbolat   +6 more
wiley   +1 more source

Evaluation of the implementation effect of pre-audit of inpatient medical orders: based on the ORTCC model. [PDF]

Front Pharmacol
Qin X, Luo S, Xi H, Xu M, Yang Y, He Q.
europepmc   +1 more source

Biodegradable Implantable Electronics with Wireless Technology for Real‐Time Clinical Applications

Advanced Healthcare Materials, EarlyView.
The article explores how bioresorbable implantable electronics merge wireless communication and power delivery with biodegradable materials to enable real‐time clinical applications. It highlights advances in materials, system design, and medical uses across neural, cardiovascular, digestive, immune, and drug‐delivery systems.
Myeongki Cho, Jeong Woo Chae, Young‐Jin Park, Ki Jun Yu, Sang Min Won   +4 more
wiley   +1 more source

Trends in mesenchymal stem cell-derived extracellular vesicles clinical trials 2014-2024: is efficacy optimal in a narrow dose range? [PDF]

Front Med (Lausanne)
Wang Y, Zhu J, Ma Q, Zhou W, Yang L, Sheng S, Zhu F, Xia Z.   +7 more
europepmc   +1 more source

Is the Safety of Finasteride Correlated With Its Route of Administration: Topical Versus Oral? A Pharmacovigilance Study With Data From the United States Food and Drug Administration Adverse Event Reporting System

Aditya K. Gupta, Mesbah Talukder, Sharon A. Keene, Mary A. Bamimore   +3 more
openalex   +1 more source

Molecular Simulations of Polymer‐based Drug Nanocarriers: From Physical and Structural Properties to Controlled Release

Advanced Healthcare Materials, EarlyView.
Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Ping Gao, Xin Jiang, Jinyu Li, Julien Nicolas, Tâp Ha‐Duong   +4 more
wiley   +1 more source

Longitudinal Patterns of Opioid and Stimulant Use by Route of Administration among People Who Inject Drugs in the South Atlantic Fentanyl Test Strip Study: A Latent Transition Analysis

Nicholas C. Peiper, Arnie Aldridge, Stephen Tueller, Judith Feinberg, Jon E. Zibbell   +4 more
openalex   +1 more source