Results 251 to 260 of about 286,603 (310)

Routes of Drug Administration

2018
Systemic absorption of a drug depends on its physicochemical properties, the nature of the dosage form on which it is included and the anatomical and physiological characteristics of the site of absorption. These considerations are important on the biopharmaceutical production and evaluation of drugs: the design of the dosage forms requires a deep ...
Ruiz, María Esperanza   +1 more
  +5 more sources

Route of Administration and Drug Disposition

Drug Metabolism Reviews, 1975
(1975). Route of Administration and Drug Disposition. Drug Metabolism Reviews: Vol. 3, No. 1, pp. 185-199.
M, Gibaldi, D, Perrier
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Route of administration and drug metabolism

European Journal of Pharmacology, 1972
Abstract Studies with ‘first-pass’ pharmacokinetic models have revealed a number of interesting characteristics in regard to the influence of route of administration on drug and metabolite levels in the tissue, the % of dose excreted in the urine as unchanged drug and the composition of total metabolites in the urine.
M, Gibaldi, S, Feldman
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Drug administration during CPR: What route?

Resuscitation, 1991
There has been considerable controversy regarding the optimum route of administration of drugs during cardiopulmonary resuscitation (CPR). Much of the confusion has arisen because the results of investigations in animals have been extrapolated to CPR in man. This may be inappropriate for a number of reasons.
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Effect of route of administration on drug disposition

Journal of Pharmacokinetics and Biopharmaceutics, 1972
An increasing body of information tends to support the hypothesis that drug effect, therapeutic or toxic, is more closely correlated with plasma concentration than dose (Levy, 1968). Absorption is one important determinant of drug plasma levels. Distribution and elimination are others.
S, Riegelman, M, Rowland
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