Results 251 to 260 of about 101,859 (303)
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Route of administration and drug metabolism
European Journal of Pharmacology, 1972Abstract Studies with ‘first-pass’ pharmacokinetic models have revealed a number of interesting characteristics in regard to the influence of route of administration on drug and metabolite levels in the tissue, the % of dose excreted in the urine as unchanged drug and the composition of total metabolites in the urine.
M, Gibaldi, S, Feldman
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Drug administration during CPR: What route?
Resuscitation, 1991There has been considerable controversy regarding the optimum route of administration of drugs during cardiopulmonary resuscitation (CPR). Much of the confusion has arisen because the results of investigations in animals have been extrapolated to CPR in man. This may be inappropriate for a number of reasons.
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Effect of route of administration on drug disposition
Journal of Pharmacokinetics and Biopharmaceutics, 1972An increasing body of information tends to support the hypothesis that drug effect, therapeutic or toxic, is more closely correlated with plasma concentration than dose (Levy, 1968). Absorption is one important determinant of drug plasma levels. Distribution and elimination are others.
S, Riegelman, M, Rowland
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Pharmaceutics and Routes of Drug Administration
2013All medicines must be administered as prescribed and following the manufacturers’ guidance. The main aim of medicines management is to achieve the desired therapeutic effect for the patient. In order to do this you need to:… ● give the correct medicine, ● at the correct dose, ● to the correct person, ● in the correct formulation, ● by the correct route,
Graham Brack +2 more
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Drug Absorption and Routes of Administration
1988We will deal here with the process of drug absorption from different sites in the body. Drug absorption, whether it be from the gastro-intestinal tract or from the buccal mucosa, requires the passage of the drug in a molecular form across the barrier membrane.
A. T. Florence, D. Attwood
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Routes of Administration and Drug Response
1975The route of administration for a drug should be selected to achieve an effective concentration at the site of action as conveniently as possible. Important subsidiary objectives may be rapidity of onset and duration of drug effect and, in some instances, selectivity of action.
C. T. Dollery, D. S. Davies
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Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies
Ca-A Cancer Journal for Clinicians, 2022Paolo Tarantino +2 more
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Cancer epigenetics in clinical practice
Ca-A Cancer Journal for Clinicians, 2023Veronica Davalos, Manel Esteller
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