Effects of oral, smoked, and vaporized cannabis on endocrine pathways related to appetite and metabolism: a randomized, double-blind, placebo-controlled, human laboratory study. [PDF]
, 2020 As perspectives on cannabis continue to shift, understanding the physiological and behavioral effects of cannabis use is of paramount importance. Previous data suggest that cannabis use influences food intake, appetite, and metabolism, yet human research
Abulseoud, Osama A +6 more
core +1 more source
Valuation implications of pharmaceutical companies' R&D regulatory approval notifications [PDF]
, 2013 This paper examines shareholder wealth effects surrounding applications to, and approvals by, the United States Food and Drug Administration (FDA) for firms listed on the New York (NYSE) and London (LSE) stock exchanges.
Hamill, P.A., McIlkenny, P., Opong, K.K.
core +1 more source
Accuracy of Dose Administered to Children Using Off-Labelled or Unlicensed Oral Dosage Forms
Pharmaceutics, 2021 The pediatric population suffers from a lack of age-appropriate medicines leading to unsafe situations when off-labelled or unlicensed drugs are used.
Guillaume Binson +6 more
doaj +1 more source
Utilizing Multi-level Classification Techniques to Predict Adverse Drug Effects and Reactions [PDF]
, 2019 Multi-class classification models are used to predict categorical response variables with more than two possible outcomes. A collection of multi-class classification techniques such as Multinomial Logistic Regression, Na\ {i}ve Bayes, and Support Vector ...
Puhl, Victoria
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SIAIP position paper: provocation challenge to antibiotics and non-steroidal anti-inflammatory drugs in children [PDF]
, 2018 Drug hypersensitivity reactions (DHRs) in childhood are mainly caused by betalactam or non-betalactam antibiotics, and non-steroidal anti-inflammatory drugs (NSAIDs).
Arasi, Stefania +19 more
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Communication of Survival Data in US Food and Drug Administration–Approved Labeling of Cancer Drugs [PDF]
, 2021 Huseyin Naci +4 more
openalex +1 more source
Enhancing the incorporation of the patient’s voice in drug development and evaluation
Research Involvement and Engagement, 2018 Plain English summary People living with a condition are uniquely positioned to inform the understanding of the therapeutic context for drug development and evaluation. In 2012, the U.S.
Meghana Chalasani +2 more
doaj +1 more source
Usefulness of body surface mapping to differentiate patients with Brugada syndrome from patients with asymptomatic Brugada syndrome. [PDF]
, 2004 We attempted to determine the usefulness of body surface mapping (BSM) for differentiating patients with Brugada syndrome (BS) from patients with asymptomatic Brugada syndrome (ABS).
Emori, Tetsuro +8 more
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Study of serious adverse drug reactions using FDA-approved drug labeling and MedDRA
BMC Bioinformatics, 2019 Background Adverse Drug Reactions (ADRs) are of great public health concern. FDA-approved drug labeling summarizes ADRs of a drug product mainly in three sections, i.e., Boxed Warning (BW), Warnings and Precautions (WP), and Adverse Reactions (AR), where
Leihong Wu +12 more
doaj +1 more source
Predicting potential adverse events using safety data from marketed drugs
BMC Bioinformatics, 2020 Background While clinical trials are considered the gold standard for detecting adverse events, often these trials are not sufficiently powered to detect difficult to observe adverse events.
Chathuri Daluwatte +4 more
doaj +1 more source