Results 21 to 30 of about 101,859 (303)

Pharmaceutical assistance in the enteral administration of drugs: choosing the appropriate pharmaceutical formulation [PDF]

Einstein (São Paulo), 2009
Objective: To study solid medications for oral delivery on the formulary of Hospital Israelita Albert Einstein (HIAE), investigating the  possibility of using these drugs through enteral feeding tubes, and recommending appropriate administration. Methods:
Gisele de Lima, Neila Maria Marques Negrini   +1 more
doaj  

Greater than the Sum: Applying Daily-Dose Equivalents to Antipsychotic Prescription Claims to Study Real-World Effects

Frontiers in Pharmacology, 2021
Traditional methods to standardize exposures in pharmacoepidemiologic studies, like defined daily-doses, may be inadequate to capture drug class effects when there are many in-class medications, formulations, and administration routes.
Kaleen N. Hayes, Tara Gomes, Tara Gomes, Tara Gomes, Tara Gomes, Mina Tadrous, Mina Tadrous, Mina Tadrous, Mina Tadrous   +8 more
doaj   +1 more source

Δ9-tetrahydrocannabinol discrimination: Effects of route of administration in mice

Drug and Alcohol Dependence Reports, 2023
Background: Route of administration is an important pharmacokinetic variable in development of translationally relevant preclinical models. Humans primarily administer cannabis through smoking, vaping, and edibles.
Julie A. Marusich, Jenny L. Wiley
doaj   +1 more source

ALTERNATIVE ROUTES OF DRUG ADMINISTRATION: ADVANTAGES AND DISADVANTAGES (SUBJECT REVIEW OF AMERICAN ACADEMY OF PEDIATRICS)

Педиатрическая фармакология, 2006
During the past 20 years advances in drug formulations and innovative routes of administration have been made. Our understanding of drug transport across tissues has increased.
article editorial
doaj   +2 more sources

Detection of serum isoniazid concentration in patients with multidrug-resistant tuberculosis using high-performance liquid chromatography

Acta Biomedica Scientifica, 2018
To study Mycobacterium tuberculosis (MTB) genotypes circulating in the Sakha Republic (Yakutia), molecular genetic analysis of multidrug-resistant MTB was performed using real-time PCR-test.
M. K. Vinokurova, O. E. Dogorova, I. S. Malogulova, E. S. Pavlova   +3 more
doaj   +1 more source

Pharmacokinetic Comparison of Three Different Administration Routes for Topotecan Hydrochloride in Rats

Pharmaceuticals, 2020
Topotecan is actively used in clinic, with its primary use being in treatment of various types of cancer. The approved administration routes are oral and intravenous.
Seung-Hyun Jeong, Ji-Hun Jang, Yong-Bok Lee   +2 more
doaj   +1 more source

Preparation Strategies of the Anti-Mycobacterial Drug Bedaquiline for Intrapulmonary Routes of Administration

Pharmaceuticals, 2023
Mycobacterium tuberculosis (M.tb) has infected one-quarter of the world’s population and led to the deaths of 1.6 million individuals in 2021 according to estimates from the World Health Organization.
Sara E. Maloney, Ian E. Stewart, Brendan K. Podell, Hadley E. Gary, Jeffrey B. Mecham, Bryan J. Berube, Susan L. Baldwin, Rhea N. Coler, Anthony J. Hickey   +8 more
doaj   +1 more source

Carrier Systems for Advanced Drug Delivery: Improving Drug Solubility/Bioavailability and Administration Routes

Pharmaceutics
The disadvantages of some conventional drugs, including their low bioavailability, poor targeting efficiency, and important side effects, have led to the rational design of drug delivery systems.
Sonia Losada-Barreiro, Sumeyye Celik, Zerrin Sezgin-Bayindir, Sofía Bravo-Fernández, Carlos Bravo-Díaz   +4 more
doaj   +1 more source

Evaluation of Drug Permeation Enhancement by Using In Vitro and Ex Vivo Models

Pharmaceuticals
Drugs administered by means of extravascular routes of drug administration must be absorbed into the systemic circulation, which involves the movement of the drug molecules across biological barriers such as epithelial cells that cover mucosal surfaces ...
Johan D. Steyn, Anja Haasbroek-Pheiffer, Wihan Pheiffer, Morné Weyers, Suzanne E. van Niekerk, Josias H. Hamman, Daniélle van Staden   +6 more
doaj   +1 more source

Falsely elevated serum testosterone measurements resulting from testosterone topical gel contamination of the venipuncture site: Case Series and retrospective review

Heliyon, 2023
Testosterone as replacement therapy for male hypogonadism or as gender-affirming hormone therapy for transgender and non-binary patients has increased worldwide.
Aranza Pinedo Pichilingue, Dina N. Greene, Matthew D. Krasowski   +2 more
doaj   +1 more source