Results 21 to 30 of about 286,603 (310)

Greater than the Sum: Applying Daily-Dose Equivalents to Antipsychotic Prescription Claims to Study Real-World Effects

open access: yesFrontiers in Pharmacology, 2021
Traditional methods to standardize exposures in pharmacoepidemiologic studies, like defined daily-doses, may be inadequate to capture drug class effects when there are many in-class medications, formulations, and administration routes.
Kaleen N. Hayes   +8 more
doaj   +1 more source

Pharmacokinetic and pharmacodynamic modelling after subcutaneous, intravenous and buccal administration of a high-concentration formulation of buprenorphine in conscious cats [PDF]

open access: yes, 2017
The aim of this study was to describe the joint pharmacokinetic-pharmacodynamic model and evaluate thermal antinociception of a high-concentration formulation of buprenorphine (Simbadol™) in ...
Beaudry, F   +6 more
core   +3 more sources

Poly(lactic-co-glycolic) acid drug delivery systems through transdermal pathway : an overview [PDF]

open access: yes, 2017
In past few decades, scientists have made tremendous advancement in the field of drug delivery systems (DDS), through transdermal pathway, as the skin represents a ready and large surface area for delivering drugs.
AE Porter   +37 more
core   +2 more sources

Evaluation of Microparticulate Ovarian Cancer Vaccine via Transdermal Route of Delivery [PDF]

open access: yes, 2016
Ovarian cancer is the fifth most commonly occurring malignancy in women, with the highest mortality rate among all the gynecological tumors. Microparticulate vaccine can serve as an immunotherapeutic approach with a promising antigenic delivery system ...
Akalkotkar, Archana   +3 more
core   +2 more sources

Δ9-tetrahydrocannabinol discrimination: Effects of route of administration in mice

open access: yesDrug and Alcohol Dependence Reports, 2023
Background: Route of administration is an important pharmacokinetic variable in development of translationally relevant preclinical models. Humans primarily administer cannabis through smoking, vaping, and edibles.
Julie A. Marusich, Jenny L. Wiley
doaj   +1 more source

Nanoparticle drug delivery systems for inner ear therapy: An overview [PDF]

open access: yes, 2017
open7noembargoed_20180701Valente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini, AlessandroValente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini,
Astolfi, Laura   +6 more
core   +2 more sources

Brain delivery of vasoactive intestinal peptide (VIP) following nasal administration to rats [PDF]

open access: yes, 2003
The aim of this work was to study in rats the nasal route for the brain delivery of the vasoactive intestinal peptide (VIP) neuropeptide. After evaluating VIP stability in solutions obtained from nasal washes, the effect of formulation parameters (pH 4-9,
Couet, William   +5 more
core   +3 more sources

Intentional and non-intentional non-adherence to medication amongst breast cancer patients [PDF]

open access: yes, 2005
This study aimed to investigate the prevalence of and factors associated with non-adherence to medication amongst a sample of breast cancer patients. 131 women with stable disease were interviewed and completed standardised psychological measures. 55% of
Demissie   +17 more
core   +1 more source

ALTERNATIVE ROUTES OF DRUG ADMINISTRATION: ADVANTAGES AND DISADVANTAGES (SUBJECT REVIEW OF AMERICAN ACADEMY OF PEDIATRICS)

open access: yesПедиатрическая фармакология, 2006
During the past 20 years advances in drug formulations and innovative routes of administration have been made. Our understanding of drug transport across tissues has increased.
article editorial
doaj   +2 more sources

Detection of serum isoniazid concentration in patients with multidrug-resistant tuberculosis using high-performance liquid chromatography

open access: yesActa Biomedica Scientifica, 2018
To study Mycobacterium tuberculosis (MTB) genotypes circulating in the Sakha Republic (Yakutia), molecular genetic analysis of multidrug-resistant MTB was performed using real-time PCR-test.
M. K. Vinokurova   +3 more
doaj   +1 more source

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