Results 201 to 210 of about 152,098 (264)

The impact of sex, species, environmental context, and alternative reinforcers in animal models of cocaine use disorders. [PDF]

Pharmacol Biochem Behav
Rough MI, Roberts BF, Nader MA.
europepmc   +1 more source

Cost-Utility Analysis of Faricimab Versus Aflibercept in Treating Neovascular Age-Related Macular Degeneration (nAMD) in the United States. [PDF]

Pharmacoecon Open
Baljoon A, Diaby V, Suther S, Dutton M, Ali A, Eljilany I.   +5 more
europepmc   +1 more source

Experimentally calibrated multiscale model predicts schedule dependent drug combination effects. [PDF]

NPJ Syst Biol Appl
Hayoun-Mya O, Montagud A, Valencia A, Ponce-de-Leon M.   +3 more
europepmc   +1 more source

Assessment of Cell-Type-Specific Excitatory Synaptic Strength in the Dorsolateral Striatum of Goal-Directed and Habitual Cocaine-Seeking Behavior. [PDF]

eNeuro
Veros KM, Timm MM, West PJ, Wilcox KS, Keefe KA.   +4 more
europepmc   +1 more source

Safety and efficacy profile of S-005151 (Redasemtide), in patients with chronic liver diseases: phase 2 trial. [PDF]

Inflamm Regen
Tsuchiya A, Watanabe Y, Kimura N, Abe H, Setsu T, Yokoo T, Kamimura H, Sakamaki A, Saito H, Tominaga M, Sato T, Kitamura N, Tanaka T, Kanemitsu Y, Ishizawa M, Miyazawa H, Tanaka M, Ishikawa H, Harada K, Tomita Y, Tamai K, Terai S.   +21 more
europepmc   +1 more source

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Acquisition of nicotine self-administration in rats: the effects of dose, feeding schedule, and drug contingency

Psychopharmacology, 1998
The studies presented here were designed to further clarify the nature of nicotine self-administration (SA) based on a limited access model in which rats are food restricted, receive operant training using food reinforcement, and are then tested in daily 1-h drug sessions.
Michelle Mielke, Eric Donny, Donny Eric C   +2 more
exaly   +3 more sources

Progressive ratio schedules in drug self-administration studies in rats: a method to evaluate reinforcing efficacy

Journal of Neuroscience Methods, 1996
Drug self-administration studies have recently employed progressive ratio (PR) schedules to examine psychostimulant and opiate reinforcement. This review addresses the technical, statistical, and theoretical issues related to the use of the PR schedule in self-administration studies in rats.
David C S Roberts, D C Roberts
exaly   +3 more sources

Defining the Optimal Schedule of Drug Administration: Art or Science?

Journal of Clinical Oncology, 2008
The optimal use of the oral fluoropyrimidine carbamate capecitabine (Xeloda; Hoffman-Roche, Nutley, NJ) has been the subject of much debate, with empirical exploration of both doses and schedules different from those approved. In the current issue of the Journal, Traina et al describe a phase I trial of a 7-day capecitabine schedule derived rationally ...
exaly   +2 more sources

Drug Administration Schedules

American Journal of Psychiatry, 1969
Common current practice is to prescribe psychotropic drugs so that a specified daily amount is administered in equally divided doses on a three to six times a day schedule. The authors contend that this procedure rests on no valid scientific basis.
A, Dimascio, R I, Shader
openaire   +3 more sources