Results 121 to 130 of about 2,169,014 (281)
Objectives This study aimed to determine whether gout flare resolution is associated with physical activity and sleep. These findings were intended to inform the future development of a definition for flare resolution. Methods Data from 81 participants with gout who experienced >1 flare during a 6‐month prospective observational study were included ...
Sarah Stewart +12 more
wiley +1 more source
Generative AI in clinical practice: how should rheumatologists evaluate and monitor emerging tools?
Generative artificial intelligence (AI) is increasingly being used in rheumatology practice, to assist with tasks such as documentation, record summarization, and clinical decision support. Rheumatologists need a practical approach to determining what evidence and oversight each application requires.
Koushan Kouranloo +2 more
wiley +1 more source
METABOLIC ACTIVITY STUDY IN PEOPLE WITH DRUG ALLERGY USING «COCKTAIL» PHENOTYPING METHOD
Study of main CYP isoforms activity using «cocktail» method was conducted on patients suffered from drug allergy with different concurrent diseases in order to determine the presence of correlation between drug allergy appearance and changes in ...
E. A. Egorenkov +3 more
doaj
In vitro tests of cellular activity form part of the diagnostic algorithm of drug hypersensitivity reactions. Because of the wide range of pharmacological mechanisms, clinical symptoms, genetic components, and laboratory tests involved, it is important ...
Gabriella Metzler +3 more
core +1 more source
Epidemiology and outcomes of geriatric patients with drug allergy
Background: Adverse drug reactions are much more common in geriatric patients but there have been no adequate studies on the epidemiology or burden of drug allergy (DA) in the elderly.
Li, PH, Wong, JCY, Lau, WCS, Chung, HY
core
Objectives This study synthesised the content and reporting completeness of published physical therapist‐led interventions for glenohumeral osteoarthritis (GHOA). Methods This systematic review undertook electronic database searches in PubMed, EMBASE, Cochrane, CINAHL and PEDro (until June 2025) for any peer‐reviewed articles/studies describing ...
Daha G Muhammad +5 more
wiley +1 more source
In vitro diagnosis of T cell-mediated drug allergy
Diagnosis of drug hypersensitivity relies on history, skin tests, in vitro tests and provocation tests. In vitro tests are of great interest, due to possible reduction of drug provocation tests.
W. J. Pichler +6 more
core +1 more source
Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu +4 more
wiley +1 more source
CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli +8 more
wiley +1 more source
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He +10 more
wiley +1 more source

