Results 121 to 130 of about 2,169,014 (281)

The association of gout flare resolution with physical activity and sleep: a prospective remote‐monitoring study

open access: yesArthritis Care &Research, Accepted Article.
Objectives This study aimed to determine whether gout flare resolution is associated with physical activity and sleep. These findings were intended to inform the future development of a definition for flare resolution. Methods Data from 81 participants with gout who experienced >1 flare during a 6‐month prospective observational study were included ...
Sarah Stewart   +12 more
wiley   +1 more source

Generative AI in clinical practice: how should rheumatologists evaluate and monitor emerging tools?

open access: yesArthritis Care &Research, Accepted Article.
Generative artificial intelligence (AI) is increasingly being used in rheumatology practice, to assist with tasks such as documentation, record summarization, and clinical decision support. Rheumatologists need a practical approach to determining what evidence and oversight each application requires.
Koushan Kouranloo   +2 more
wiley   +1 more source

METABOLIC ACTIVITY STUDY IN PEOPLE WITH DRUG ALLERGY USING «COCKTAIL» PHENOTYPING METHOD

open access: yesРазработка и регистрация лекарственных средств, 2019
Study of main CYP isoforms activity using «cocktail» method was conducted on patients suffered from drug allergy with different concurrent diseases in order to determine the presence of correlation between drug allergy appearance and changes in ...
E. A. Egorenkov   +3 more
doaj  

Analysis of Viability as Readout of Lymphocyte Transformation Test in Drug Hypersensitivity Diagnostics

open access: yes
In vitro tests of cellular activity form part of the diagnostic algorithm of drug hypersensitivity reactions. Because of the wide range of pharmacological mechanisms, clinical symptoms, genetic components, and laboratory tests involved, it is important ...
Gabriella Metzler   +3 more
core   +1 more source

Epidemiology and outcomes of geriatric patients with drug allergy

open access: yes, 2020
Background: Adverse drug reactions are much more common in geriatric patients but there have been no adequate studies on the epidemiology or burden of drug allergy (DA) in the elderly.
Li, PH, Wong, JCY, Lau, WCS, Chung, HY
core  

The content and reporting completeness of physical therapist‐led interventions for glenohumeral osteoarthritis: a systematic review

open access: yesArthritis Care &Research, Accepted Article.
Objectives This study synthesised the content and reporting completeness of published physical therapist‐led interventions for glenohumeral osteoarthritis (GHOA). Methods This systematic review undertook electronic database searches in PubMed, EMBASE, Cochrane, CINAHL and PEDro (until June 2025) for any peer‐reviewed articles/studies describing ...
Daha G Muhammad   +5 more
wiley   +1 more source

In vitro diagnosis of T cell-mediated drug allergy

open access: yes, 2011
Diagnosis of drug hypersensitivity relies on history, skin tests, in vitro tests and provocation tests. In vitro tests are of great interest, due to possible reduction of drug provocation tests.
W. J. Pichler   +6 more
core   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

open access: yesAdvanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu   +4 more
wiley   +1 more source

Topically Delivered Treg‐Attracting Microparticle‐Hydrogel Composites Recruit Regulatory T Cells and Limit Cardiac Injury After Severe Ischemia

open access: yesAdvanced Healthcare Materials, EarlyView.
CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli   +8 more
wiley   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

open access: yesAdvanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He   +10 more
wiley   +1 more source

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