Results 161 to 170 of about 1,842 (205)
Some of the next articles are maybe not open access.
New England Journal of Medicine, 1951
THE seventeenth century must have been the nadir of therapeutics, if we can believe Moliere, for one of his characters remarks: "Almost everyone dies of the remedy, not the malady." Fortunately, si...
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THE seventeenth century must have been the nadir of therapeutics, if we can believe Moliere, for one of his characters remarks: "Almost everyone dies of the remedy, not the malady." Fortunately, si...
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Primary Care: Clinics in Office Practice, 1998
Allergic drug reactions are a significant cause of morbidity and mortality. Because it is difficult to identify the culprit drug and the underlying pathophysiologic mechanisms involved in these reactions, a systematic approach should be adopted in the evaluation of drug-allergic patients. Initially, the type of reaction should be determined.
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Allergic drug reactions are a significant cause of morbidity and mortality. Because it is difficult to identify the culprit drug and the underlying pathophysiologic mechanisms involved in these reactions, a systematic approach should be adopted in the evaluation of drug-allergic patients. Initially, the type of reaction should be determined.
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Journal of Allergy and Clinical Immunology, 2010
Drug allergy is one type of adverse reaction to drugs and encompasses a spectrum of hypersensitivity reactions with heterogeneous mechanisms and clinical presentations. A thorough history is essential to the management of drug allergy. Laboratory testing has a very limited role in the management of drug allergy. Graded dose challenges and procedures to
David A, Khan, Roland, Solensky
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Drug allergy is one type of adverse reaction to drugs and encompasses a spectrum of hypersensitivity reactions with heterogeneous mechanisms and clinical presentations. A thorough history is essential to the management of drug allergy. Laboratory testing has a very limited role in the management of drug allergy. Graded dose challenges and procedures to
David A, Khan, Roland, Solensky
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Medical Clinics of North America, 1992
Although allergic drug reactions are just one type of adverse reaction to medications, they are clinically very important because of the morbidity and mortality they cause. An ever-expanding pharmacopeia increases the potential for allergic drug reactions.
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Although allergic drug reactions are just one type of adverse reaction to medications, they are clinically very important because of the morbidity and mortality they cause. An ever-expanding pharmacopeia increases the potential for allergic drug reactions.
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Clinical Reviews in Allergy & Immunology, 2015
While peripheral or tissue eosinophilia may certainly characterize drug eruptions, this feature is hardly pathognomonic for a medication-induced etiology. While delayed drug hypersensitivity reactions with prominent eosinophilic recruitment have been typically classified as type IVb reactions, their pathophysiology is now known to be more complex ...
Merin, Kuruvilla, David A, Khan
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While peripheral or tissue eosinophilia may certainly characterize drug eruptions, this feature is hardly pathognomonic for a medication-induced etiology. While delayed drug hypersensitivity reactions with prominent eosinophilic recruitment have been typically classified as type IVb reactions, their pathophysiology is now known to be more complex ...
Merin, Kuruvilla, David A, Khan
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Immunology and Allergy Clinics of North America, 2014
Poorly documented and often self-reported drug hypersensitivity (DH) is a frequent problem in daily clinical practice and has a considerable impact on prescription choices. Little is known about the natural history of true DH. The suspicion of DH starts on clinical grounds.
Anca M, Chiriac, Pascal, Demoly
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Poorly documented and often self-reported drug hypersensitivity (DH) is a frequent problem in daily clinical practice and has a considerable impact on prescription choices. Little is known about the natural history of true DH. The suspicion of DH starts on clinical grounds.
Anca M, Chiriac, Pascal, Demoly
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Immunology Today, 1998
Abstract Against the background of advances in our knowledge of antigen recognition at the molecular level, a recent meeting1The International Symposium on Adverse Drug Reactions with an Immunological Basis was held at Puerto de Santa Maria, Spain, on 19–22 November 1997. 1 reconsidered how the immune system recognizes and responds to drugs.
J W, Coleman, M, Blanca
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Abstract Against the background of advances in our knowledge of antigen recognition at the molecular level, a recent meeting1The International Symposium on Adverse Drug Reactions with an Immunological Basis was held at Puerto de Santa Maria, Spain, on 19–22 November 1997. 1 reconsidered how the immune system recognizes and responds to drugs.
J W, Coleman, M, Blanca
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Desensitization for drug allergy
Current Opinion in Allergy and Clinical Immunology, 2006Desensitization for drug allergy is the induction of temporary clinical unresponsiveness to drug antigens. Gradual reintroduction of small doses of drug antigen at fixed time intervals allows for the delivery of full therapeutic doses, protecting patients from anaphylaxis.
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Current Opinion in Allergy and Clinical Immunology, 2001
Drug-related rashes have been estimated to be 100 times more common in HIV-positive patients than in the general population. The reasons for this are not clear, but are likely to be multifactorial, and include changes in drug metabolism, oxidative stress, cytokine profiles and immune hyperactivation.
M, Pirmohamed, B K, Park
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Drug-related rashes have been estimated to be 100 times more common in HIV-positive patients than in the general population. The reasons for this are not clear, but are likely to be multifactorial, and include changes in drug metabolism, oxidative stress, cytokine profiles and immune hyperactivation.
M, Pirmohamed, B K, Park
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Current Opinion in Allergy & Clinical Immunology, 2020
Purpose of reviewAs drug allergy research aims to inform clinical practice, implementation of best practices may be influenced by financial resources required to incorporate new interventions and the resulting clinical and economic returns on those resource investments.
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Purpose of reviewAs drug allergy research aims to inform clinical practice, implementation of best practices may be influenced by financial resources required to incorporate new interventions and the resulting clinical and economic returns on those resource investments.
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