Results 201 to 210 of about 2,169,014 (281)

The Mixed Neutrophilic–Eosinophilic Endotype of CRSwNP Blunts Postsurgical Improvement as Determined by the Completeness of Surgery Index

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background The Completeness of Surgery Index (CoSI) is a novel metric for assessing surgical quality in chronic rhinosinusitis with nasal polyps (CRSwNP). Structured histopathology (SHP) is helpful for characterizing drivers of inflammation. Integrating these two tools to identify patients at higher risk for surgically recalcitrant disease has
Vidit M. Talati, Kerol Faltas, Michael R. Xiang, Randy Bach, Spencer L. Yueh, Margaret B. Mitchell, Alan D. Workman, Michael A. Kohanski, Nithin D. Adappa, Jennifer E. Douglas, Noam A. Cohen, John V. Bosso, James N. Palmer   +12 more
wiley   +1 more source

Intermolecular Carbon–Carbon Naphthalene Coupling Involves a Radical Mechanism Driven by Cytochrome P450 in Alternaria alternata

Angewandte Chemie, EarlyView.
1,8‐DHN is an important intermediate to form complex aromatic ring systems. Phenol‐coupling reactions are important for the dimerization of two molecules. Here, we show that a fungal cytochrome P450 enzyme catalyzes specific C─C bonds. ABSTRACT Dihydroxynaphthalene (DHN) derivatives are precursors of biologically important molecules, including melanin ...
Jia Gao, Leyao Chen, Karin Steffen, Henrik Schweder, Birgit Schreckenberger, Shu‐Ming Li, Ben Auxier, Antonis Rokas, Reinhard Fischer   +8 more
wiley   +2 more sources

Circulating Exosomes Drive Persistent Neuronal Dysfunction in Post‐Herpetic Neuralgia Patients

Annals of Neurology, EarlyView.
Proposed model of exosome‐mediated neuronal dysfunction in post‐herpetic neuralgia (PHN). (1) Circulating, non‐pathogenic exosomes maintain homeostatic processes in healthy skin, where sensory nerve fibers innervate the epidermis and dermis. (2) During acute zoster, reactivating varicella zoster virus (VZV) travels down neurites to the skin causing ...
Christy S. Niemeyer, Seth Frietze, Serena W.R. Lewis, Emily C. Artman, Christina Coughlan, Safa I. Vaseemuddin, Arianna Gentile Polese, Maria A. Nagel, Stephen K. Tyring, Fyona Okundia, Anthony J. Saviola, Gary C. Curhan, Sharon G. Curhan, Diego Restrepo, Andrew N. Bubak   +14 more
wiley   +1 more source

From burden to breakthrough: Advances in hereditary angioedema, drug allergy, and allergic disease prevention. [PDF]

Allergy Asthma Proc
Bellanti JA, Settipane RA.
europepmc   +1 more source

Synthetic Particulate Subunit Vaccines Co‐Delivering Multiple Antigens Induce Protective Immunity Against Melioidosis

Advanced NanoBiomed Research, EarlyView.
Engineered endotoxin‐free Escherichia coli were used to assemble poly(3‐hydroxybutyrate) (PHB) biopolymer particles displaying multiple conserved Burkholderia pseudomallei antigens via PhaC‐mediated surface presentation. Following formulation with poly(I:C), the particulate vaccines induced antigen‐specific humoral and cellular immune responses ...
Md. Tanvir Kabir, Shuxiong Chen, Justine B. Bendo, Ashley Johnson, Aleksandra W. Debowski, Mitali Sarkar‐Tyson, Bernd H. A. Rehm   +6 more
wiley   +1 more source

Nonirritating concentration of intradermal cefepime skin test in patients undergoing drug allergy evaluation. [PDF]

J Allergy Clin Immunol Pract
Accarino JJO, Shah RJ, Smith LR, Norton DT, Banerji A, Waldron JL, Blumenthal KG.   +6 more
europepmc   +1 more source

Evaluation of cephalosporin allergy: Survey of drug allergy experts. [PDF]

J Allergy Clin Immunol Glob
Brameli A, Stone CA, Phillips EJ.
europepmc   +1 more source

Stability of diluted chlorhexidine for skin testing in drug allergy evaluations. [PDF]

J Allergy Clin Immunol Glob
Shah D, Cojuc-Konigsberg G, Brown SD, Chiarella SE, Volcheck GW, Kita H, Garvey LH, Gonzalez-Estrada A.   +7 more
europepmc   +1 more source

Real‐World Treatment Escalation Patterns of Biologics and Functional Endoscopic Sinus Surgery in Chronic Rhinosinusitis (CRS): A Nationwide Database Study

International Forum of Allergy &Rhinology, EarlyView.
Omer Baker, Bita Naimi, Soraya Mehdipour, Adam S. Deconde, Carol H. Yan   +4 more
wiley   +1 more source

Does Self-Reported Drug Allergy Influence Clinically Significant Outcome Improvement and Graft Failure Rates After Meniscal Allograft Transplantation of the Knee? [PDF]

Orthop J Sports Med
Sachs JP, Mufti YN, Franzia CH, Muth SA, Bi AS, Cole BJ.   +5 more
europepmc   +1 more source