Results 211 to 220 of about 4,110,090 (330)

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

Advanced Science, EarlyView.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini, Taylor V. Brysgel, Ryan J. Rahman, Eno‐Obong Essien, Saw Y. Nwe, Jichuan Wu, Aparajeeta Majumder, Manthan N. Patel, Sachchidanand Tiwari, Carolann L. Espy, Fengyi Dong, Sabrina A. Santos‐De León, Anit Shah, Vladimir V. Shuvaev, Elizabeth D. Hood, Liam S. Chase, Drew Weissman, Jeremy B. Katzen, David B. Frank, Mariko L. Bennett, Oscar A. Marcos‐Contreras, Jacob W. Myerson, Vladimir R. Muzykantov, Sahily Reyes‐Esteves, Jacob S. Brenner   +24 more
wiley   +1 more source

Global differences and risk factors influencing drug hypersensitivity quality of life: A multicenter, multiethnic study of drug allergy across 3 continents. [PDF]

J Allergy Clin Immunol Glob
Copaescu AM, Mak HWF, Vogrin S, Holmes NE, Trubiano JA, Li PH.   +5 more
europepmc   +1 more source

Shared Interoperable Clinical Decision Support Service for Drug-Allergy Interaction Checks: Implementation Study.

JMIR Med Inform, 2022
Jung S, Bae S, Seong D, Oh OH, Kim Y, Yi BK.   +5 more
europepmc   +1 more source

Psychological profiles of patients with suspected drug allergy. [PDF]

Asia Pac Allergy, 2020
Dias de Castro E, Leblanc A, Barbosa J, Ribeiro L, Cernadas JR.   +4 more
europepmc   +1 more source

Advances in Drug Allergy, Urticaria, Angioedema and Anaphylaxis in 2018.

Journal of Allergy and Clinical Immunology, 2019
Rachel L. Miller, Maria Shtessel, L. Robinson, A. Banerji   +3 more
semanticscholar   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

When leuprolide acetate is essential to care: A review of the literature and framework for assessing drug allergy. [PDF]

J Allergy Clin Immunol Glob
Belmont AP, Rosano J, Criscione J, Stone CA, Leeds S.   +4 more
europepmc   +1 more source

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα

Advanced Science, EarlyView.
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan, Xinru Xi, Wei Dai, Tingfang Xiao, Yeqing Chen, Xuanyu Chen, Xiangting Ge, Chengguang Zhao, Hui Zhang, Yali Zhang, Weixi Zhang   +10 more
wiley   +1 more source

Challenge testing and quality of life in adults with suspected drug or food allergies [PDF]

Lujain Majdi M Qutub, Genevieve Bouvette, Florian Stehlin, Connor Prosty, Ghislaine Annie Clarisse Isabwe   +4 more
openalex   +1 more source

What can we learn in drug allergy management from World Health Organization's international classifications?

Allergy. European Journal of Allergy and Clinical Immunology, 2018
L. Tanno, M. J. Torres, Mariana Castells, Pascal Demoly   +3 more
semanticscholar   +1 more source