Results 141 to 150 of about 207,835 (296)

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Studies on Thermal Aggregation of Bovine Serum Albumin as a Drug Carrier.

, 2000
Chikako Honda, Hiroko Kamizono, Tatsuya Samejima, Kazutoyo Endo   +3 more
openalex   +2 more sources

Small molecular drug transfer across the blood-brain barrier via carrier-mediated transport systems [PDF]

, 2005
Akira Tsuji
openalex   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Interaction of sulfasalazine with outer surface of boron-nitride nanotube as a drug carrier in aqueous solution: insights from quantum mechanics and Monte Carlo simulation. [PDF]

BMC Chem, 2023
Ketabi S, Shalmashi S, Hallajian S.
europepmc   +1 more source

Polymeric drug carriers.

, 2001
Yuichi Ohya, Tatsuro Ouchi
openalex   +2 more sources

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

Molecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun, Ching‐Fang Yu, Sheng‐Yan Wu, Wei‐Chung Cheng, Chi‐Shiun Chiang, Fang‐Hsin Chen   +5 more
wiley   +1 more source

Crosslinked Chitosan-Gelatin Biocompatible Nanocomposite as a Neuro Drug Carrier. [PDF]

ACS Omega, 2022
Mathew SA, Arumainathan S.
europepmc   +1 more source

Characteristics of Tissue Distribution of Various Polysaccharides as Drug Carriers: Influences of Molecular Weight and Anionic Charge on Tumor Targeting

, 2001
Shu-ichi Sugahara, Satoshi Okuno, Toshiro Yano, Hiroshi Hamana, Kazuhiro Inoue   +4 more
openalex   +2 more sources

Poly(ethylene oxide)-b-poly(N-isopropylacrylamide) nanoparticles with cross-linked cores as drug carriers [PDF]

, 2005
Yi Zeng, William G. Pitt
openalex   +1 more source