Results 141 to 150 of about 5,260,545 (402)

MICROSPHERES: A PROMISING DRUG CARRIER

, 2016
Microsphere as a drug carrier is one of the method of delivering therapeutic agent to the target site in a sustained and controlled manner. Microspheres are defined as free flowing powders of spherical shape, consisting of proteins or synthetic polymers,
V. Rastogi, S. S. Shukla, Roopse Singh, N. Lal, Pragya Yadav   +4 more
semanticscholar   +1 more source

drug carrier

Citation: 'drug carrier' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13931 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Numerical Simulation in Microvessels for the Design of Drug Carriers with the Immersed Boundary-Lattice Boltzmann Method

Micromachines
This study employs numerical techniques to investigate the motion characteristics of red blood cells (RBCs) and drug carriers (DCs) within microvessels. A coupled model of the lattice Boltzmann method (LBM) and immersed boundary method (IBM) is proposed ...
Yulin Hou, Mengdan Hu, Dongke Sun, Yueming Sun   +3 more
doaj   +1 more source

Outlook on the Application of Metal-Liganded Bioactives for Stimuli-Responsive Release

Molecules, 2017
Direct metal-liganded bioactive coordination complexes are known to be sensitive to stimuli such as pH, light, ion activation, or redox cues. This results in the controlled release of the bioactive(s).
Gretta C. M’bitsi-Ibouily, Thashree Marimuthu, Pradeep Kumar, Lisa C. du Toit, Yahya E. Choonara, Pierre P. D. Kondiah, Viness Pillay   +6 more
doaj   +1 more source

Intranasal infusion of nanostructured lipid carriers (NLC) containing CNS acting drug and estimation in brain and blood [PDF]

, 2013
Mohammad Intakhab Alam, Sanjula Baboota, Alka Ahuja, Mushir Ali, Javed Ali, Jasjeet Kaur Sahni   +5 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

NO-cGMP-K⁺ Channels Pathways Participate in the Antihypertensive Effects of Attalea phalerata Martius ex Spreng Oil-Loaded Nanocapsules

Pharmaceutics
Attalea phalerata Martius ex Spreng is a palm tree that is widely distributed in the Central-West region of Brazil. In this study, we investigated whether the oil-loaded nanocapsules of A.
Maria Medina de Azevedo, Francislaine Aparecida dos Reis Lívero, Sílvia Beatriz Bürger Tinelli, Jacenir Vieira da Silva, Danielle Ayr Tavares de Almeida, Marco Antonio Utrera Martines, Ariadna Lafourcade Prada, Jesús Rafael Rodríguez Amado, Arquimedes Gasparotto Junior   +8 more
doaj   +1 more source

A Comprehensive review on Niosome: a prominent carrier in advance drug delivery

, 2022
Arun Kumar, Kapil Kumar, Aparna Joshi, Ikram Ikram, Deepak Teotia   +4 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source