In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna+4 more
wiley +1 more source
Introducing carbon quantum dot-Capivasertib drug carrier complex for enhanced treatment of breast cancer. [PDF]
Rahmandoust M, Abdolrahimi S.
europepmc +1 more source
Investigation of the Drug Carrier Properties of Insoluble Cyclodextrin Polymer Microspheres. [PDF]
Haimhoffer Á+13 more
europepmc +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source
PEGylated Silk Fibroin Nanoparticles for Oral Antibiotic Delivery: Insights into Drug-Carrier Interactions and Process Greenness. [PDF]
Pham DT+8 more
europepmc +1 more source
Strategies to overcome the main challenges of the use of exosomes as drug carrier for cancer therapy. [PDF]
Hussen BM+7 more
europepmc +1 more source
Starch-based microspheres produced by emulsion crosslinking with a potential media dependent responsive behavior to be used as drug delivery carriers [PDF]
Patrícia B. Malafaya+2 more
openalex +1 more source
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki+11 more
wiley +1 more source
Stability and Rheological Properties of the Novel Silica-Based Organogel-A Drug Carrier with High Solubilization Potential. [PDF]
Suwiński G, Nowak I.
europepmc +1 more source
Development of a quaternary ammonium poly (amidoamine) dendrimer-based drug carrier for the solubility enhancement and sustained release of furosemide. [PDF]
Murugan E, Yogaraj V.
europepmc +1 more source