Results 11 to 20 of about 207,835 (296)

Dual role of nanoparticles as drug carrier and drug [PDF]

open access: yesCancer Nanotechnology, 2011
The conventional chemotherapeutic agents used in the treatment of human malignancies are directed nonspecifically against both malignant and nonmalignant cells, often limiting their efficacy with having serious side effects. Recent development of drug delivery vehicles has opened up the possibility of targeted drug delivery systems with the potential ...
Patra, Hirak Kumar   +4 more
openaire   +3 more sources

Proof-of-Concept for Adjusted Surface Energies and Modified Fines as a Novel Concept in Particle Engineering for DPI Formulations

open access: yesPharmaceutics, 2022
Currently marketed dry powder inhaler (DPI) medicine lacks drug delivery performance due to insufficient powder dispersion. In carrier-based blends, incomplete drug detachment is typically attributed to excessive adhesion forces between carrier and drug ...
Nicholas Bungert   +2 more
doaj   +1 more source

Mixing time effects on the dispersion performance of adhesive mixtures for inhalation. [PDF]

open access: yesPLoS ONE, 2013
This paper deals with the effects of mixing time on the homogeneity and dispersion performance of adhesive mixtures for inhalation. Interactions between these effects and the carrier size fraction, the type of drug and the inhalation flow rate were ...
Floris Grasmeijer   +3 more
doaj   +1 more source

A Rapid Dual-Responsive Releasing Nano-Carrier by Decomposing the Copolymer and Reversing the Core Dissolution

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
The accumulation of nanotechnology-based drugs has been realized in various ways. However, the concentration of drugs encapsulated by nanomaterials is not equal to the concentration of effective drugs; often, the drugs become effective only when they are
Sen Liu   +8 more
doaj   +1 more source

Aptamers as Both Drugs and Drug-Carriers [PDF]

open access: yesBioMed Research International, 2014
Aptamers are short nucleic acid oligos. They may serve as both drugs and drug-carriers. Their use as diagnostic tools is also evident. They can be generated using various experimental, theoretical, and computational techniques. The systematic evolution of ligands by exponential enrichment which uses iterative screening of nucleic acid libraries is a ...
openaire   +2 more sources

Development of Computational In Silico Model for Nano Lipid Carrier Formulation of Curcumin

open access: yesMolecules, 2023
The oral delivery system is very important and plays a significant role in increasing the solubility of drugs, which eventually will increase their absorption by the digestive system and enhance the drug bioactivity.
Omar Waleed Abduljaleel Albasri   +2 more
doaj   +1 more source

Preparation and use of nanogels as carriers of drugs [PDF]

open access: yesDrug Delivery, 2021
Nanogels have high tunability and stability while being able to sense and respond to external stimuli by showing changes in the gel volume, water content, colloidal stability, mechanical strength, and other physical/chemical properties. In this article, advances in the preparation of nanogels will be reviewed.
Wing-Fu Lai   +3 more
openaire   +4 more sources

Multi-Functional Drug Carrier Micelles With Anti-inflammatory Drug

open access: yesFrontiers in Chemistry, 2019
The multi-functional micelles poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide-co-10 undecanoic acid)/CM-Dextran Fe3O4 (PNDU/CM-Dex Fe3O4) were poly (NIPAAm-co-DMAAm-co-UA) (PNDU) grafting hydrophilic CM-Dextran Fe3O4 which possess pH-dependent ...
Wei-Jie Wang   +4 more
doaj   +1 more source

Drug carrier systems

open access: yesVaccine, 1990
Journal of Controlled Release 12 (1990) 181-181.
College of Pharmacy University of Florida U.S.A. ( host institution )   +1 more
openaire   +5 more sources

Near-infrared light-triggered nitric oxide release combined with low-temperature photothermal therapy for synergetic antibacterial and antifungal

open access: yesSmart Materials in Medicine, 2021
In recent years, nitric oxide (NO) has been widely studied as a non-drug resistant antimicrobial agent, but the issue of low NO loading capacity as well as premature leakage during transportation limit its further application. Herein, we have developed a
Lu Liu   +4 more
doaj  

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