Results 21 to 30 of about 5,260,545 (402)

Proof-of-Concept for Adjusted Surface Energies and Modified Fines as a Novel Concept in Particle Engineering for DPI Formulations

open access: yesPharmaceutics, 2022
Currently marketed dry powder inhaler (DPI) medicine lacks drug delivery performance due to insufficient powder dispersion. In carrier-based blends, incomplete drug detachment is typically attributed to excessive adhesion forces between carrier and drug ...
Nicholas Bungert   +2 more
doaj   +1 more source

Multifunctional nanocarriers for lung drug delivery [PDF]

open access: yes, 2020
Nanocarriers have been increasingly proposed for lung drug delivery applications. The strategy of combining the intrinsic and more general advantages of the nanostructures with specificities that improve the therapeutic outcomes of particular clinical ...
Grenha, Ana, Pontes, Jorge Filipe
core   +2 more sources

Comparative study of the potential of poly(2-ethyl-2-oxazoline) as carrier in the formulation of amorphous solid dispersions of poorly soluble drugs [PDF]

open access: yes, 2019
Despite the fact that solid dispersions are gaining momentum, the number of polymers that have been used as a carrier during the past 50 years is rather limited.
Boel, Eline   +5 more
core   +1 more source

Nanoparticles in the treatment of chronic lung diseases [PDF]

open access: yes, 2019
Nanoparticles, although considered a topic of modern medicine, actually have an interesting history. Currently, advances in nanomedicine hold great promise as drug carrier systems for sustained release and targeted delivery of diverse therapeutic agents.
Alexescu, Teodora G   +9 more
core   +2 more sources

Adverse reactions of amiodarone [PDF]

open access: yes, 2019
Adverse drug reaction is defined by the World Health Organization as any response to a drug that is noxious and unintended and occurs at a dose normally used in man.
Calvosa, Leonardo   +5 more
core   +1 more source

Mixing time effects on the dispersion performance of adhesive mixtures for inhalation. [PDF]

open access: yesPLoS ONE, 2013
This paper deals with the effects of mixing time on the homogeneity and dispersion performance of adhesive mixtures for inhalation. Interactions between these effects and the carrier size fraction, the type of drug and the inhalation flow rate were ...
Floris Grasmeijer   +3 more
doaj   +1 more source

A Rapid Dual-Responsive Releasing Nano-Carrier by Decomposing the Copolymer and Reversing the Core Dissolution

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
The accumulation of nanotechnology-based drugs has been realized in various ways. However, the concentration of drugs encapsulated by nanomaterials is not equal to the concentration of effective drugs; often, the drugs become effective only when they are
Sen Liu   +8 more
doaj   +1 more source

Microfluidics for core–shell drug carrier particles – a review

open access: yesRSC Advances, 2020
Core–shell drug-carrier particles are known for their unique features. Due to the combination of superior properties not exhibited by the individual components, core–shell particles have gained a lot of interest.
Sepideh Yazdian Kashani   +3 more
semanticscholar   +1 more source

Indometacin loading and in vitro release properties from novel carbopol coated spherical mesoporous silica nanoparticles [PDF]

open access: yes, 2013
Spherical MCM-41 silica nanosized particles were synthesized and post synthesis modified by 3-aminopropyltriethoxysilane (APTES) in order to prepare amino-functionalized carrier.
Agnes Szegedi   +36 more
core   +1 more source

Surfactant as a drug carrier

open access: yesSeminars in Fetal and Neonatal Medicine, 2023
Drug delivery using a surfactant vehicle has the potential to prevent systemic side effects by delivering therapeutic agents directly to the respiratory system. The inherent chemical properties of surfactant allows it to readily distribute throughout the respiratory system.
Arun, Sett   +2 more
openaire   +2 more sources

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