Results 331 to 340 of about 5,260,545 (402)
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Life Sciences, 1977
Abstract The use of liposomes as drug carrying vehicles are summarized. Introduction of smaller doses, increased permeability, reduced toxicological and allergic effects and altered immunological responses are the advantages of the method. Experimental techniques for the preparation of drug containing liposomes and for their deliveries are surveyed ...
J H, Fendler, A, Romero
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Abstract The use of liposomes as drug carrying vehicles are summarized. Introduction of smaller doses, increased permeability, reduced toxicological and allergic effects and altered immunological responses are the advantages of the method. Experimental techniques for the preparation of drug containing liposomes and for their deliveries are surveyed ...
J H, Fendler, A, Romero
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Drug carriers for vascular drug delivery
IUBMB Life, 2011AbstractThe currently used drug carriers for vascular drug delivery are reviewed. The human vascular system possesses unique physiological features that can be exploited for enhanced and effective targeted drug delivery. Although the thin layer of endothelial cells (EC) lines the interior surface of blood vessels forming an interface between ...
Erez, Koren, Vladimir P, Torchilin
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Advances in Materials, 2019
To stress the role of deoxyribonucleic acid (DNA) as a drug carrier, an efficient conjugation strategy in which chemotherapeutics can be grafted onto a phosphorothiolated DNA backbone through the reaction between the phosphorothioate group (PS) and a ...
Yuanyuan Guo +7 more
semanticscholar +1 more source
To stress the role of deoxyribonucleic acid (DNA) as a drug carrier, an efficient conjugation strategy in which chemotherapeutics can be grafted onto a phosphorothiolated DNA backbone through the reaction between the phosphorothioate group (PS) and a ...
Yuanyuan Guo +7 more
semanticscholar +1 more source
Engineering in Medicine, 1986
Site-specific drug carriers are required to exclusively deliver drug molecules to difficult targets within the body. They should do so in a form which protects the drug and host from one another. This contribution reviews the reasons for drug targeting, and describes some of the features required of two types of carrier system, i.e., particulates and ...
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Site-specific drug carriers are required to exclusively deliver drug molecules to difficult targets within the body. They should do so in a form which protects the drug and host from one another. This contribution reviews the reasons for drug targeting, and describes some of the features required of two types of carrier system, i.e., particulates and ...
openaire +2 more sources
Carrier Deformability in Drug Delivery
Current Pharmaceutical Design, 2016Deformability is a key property of drug carriers used to increase the mass penetration across the skin without disrupting the lipid barrier. Highly deformable vesicles proved to be more effective than conventional liposomes in delivering drugs into and across the mammalian skin upon topical non occlusive application.
Morilla, María José +1 more
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Biocompatibility and in vivo degradation of chitosan based hydrogels as potential drug carrier
Journal of Biomaterials Science. Polymer Edition, 2018Carboxymethyl chitosan-graft-polylactide (CMCS-PLA) and carboxymethyl chitosan (CMCS) hydrogels were prepared by using 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) as crosslinking agent and catalyst at room ...
F. Su +7 more
semanticscholar +1 more source
Polymeric microspheres as drug carriers
Biomaterials, 1988The use of polymeric microsphere systems (including polypeptides) as vehicles for delivering drugs by a variety of routes is considered with particular reference to parenteral administration. Microsphere formulation is discussed with emphasis on the role of surface properties and how these can determine the fate of administered particles.
S S, Davis, L, Illum
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Albumin-Based Nanodevices as Drug Carriers
Current Pharmaceutical Design, 2016Nanomedicine, the application of nanotechnology to medicine, is being increasingly used to improve and exploit the advantages of efficient drug delivery. Different nanodevices have been developed in recent years, among them protein-based nanoparticles which have gained considerable interest.
Loureiro, Ana Isabel Sá +3 more
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Driving forces for drug loading in drug carriers
Journal of Microencapsulation, 2015The loading capacity of a drug carrier is determined essentially by intermolecular interactions between drugs and carrier materials. In this review, the process of drug loading is described in detail based on the differences in the driving force for drug incorporation, including hydrophobic interaction, electrostatic interaction, hydrogen bonding, Pi ...
Yang, Li, Li, Yang
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Peptide vectors as drug carriers
2003During the last decade, several peptides have been described, such as SynB vectors [1] penetratin and Tat [2, 3] that allow the intracellular delivery of polar, biologically active compounds in vitro and in vivo [2, 4]. These peptides, belonging to various families, are heterogeneous in size (10 to 18 amino acids) and sequence (Tab. 1).
Jamal, Temsamani +1 more
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