Results 31 to 40 of about 207,835 (296)
Acta Pharmaceutica Sinica B, 2012 Atorvastatin has low aqueous solubility resulting in low oral bioavailability (12%) and thus presents a challenge in formulating a suitable dosage form.
Ankush Choudhary +4 more
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Liposome: a carrier for effective drug delivery
Journal of Applied Pharmaceutical Research, 2020 Liposomes are the spherical vesicles containing one or more phospholipid bilayer, which was first described in the middle of 60s by Bangham. The bilayer vesicles are considered as an efficient carrier for drug delivery, diagnostic agents, and also an ...
Ananta Choudhury +4 more
doaj +1 more source
Research progress of calcium carbonate nanomaterials in cancer therapy: challenge and opportunity
Frontiers in Bioengineering and Biotechnology, 2023 Cancer has keeping the main threat to the health of human being. Its overall survival rate has shown rare substantial progress in spite of the improving diagnostic and treatment techniques for cancer in recent years.
Tiantian Liang +16 more
doaj +1 more source
Cyclodextrin-based nanosponges as drug carriers [PDF]
Beilstein Journal of Organic Chemistry, 2012 Cyclodextrin-based nanosponges, which are proposed as a new nanosized delivery system, are innovative cross-linked cyclodextrin polymers nanostructured within a three-dimensional network. This type of cyclodextrin polymer can form porous insoluble nanoparticles with a crystalline or amorphous structure and spherical shape or swelling properties.
TROTTA, Francesco +2 more
openaire +5 more sources
The emerging role of extracellular vesicles in fungi: a double-edged sword
Frontiers in Microbiology, 2023 Fungi are eukaryotic microorganisms found in nature, which can invade the human body and cause tissue damage, inflammatory reactions, organ dysfunctions, and diseases.
Yi Lai +7 more
doaj +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Augmenting drug–carrier compatibility improves tumour nanotherapy efficacy
Nature Communications, 2016 The in vivoanticancer efficacy of nanoparticle-mediated drug delivery depends on the association between the drug and its carrier. Here, the authors use FRET to show that the drug hydrophobicity, and miscibility with the carrier, influence nanoparticle ...
Yiming Zhao +12 more
doaj +1 more source
Preparation and Self-Assembly of pH-Responsive Hyperbranched Polymer Peptide Hybrid Materials
Nanomaterials, 2023 In recent years, the coupling of structurally and functionally controllable polymers with biologically active peptide materials to obtain polymer-peptide hybrids with excellent properties and biocompatibility has led to important research progress in the
Yan Qin, Jianguo Yi, Yue Zhang
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Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Bacterial Drug Delivery Systems for Cancer Therapy: “Why” and “How”
Pharmaceutics, 2023 Cancer is one of the major diseases that endanger human health. However, the use of anticancer drugs is accompanied by a series of side effects. Suitable drug delivery systems can reduce the toxic side effects of drugs and enhance the bioavailability of ...
Xiangcheng Zhao +4 more
doaj +1 more source