Results 51 to 60 of about 5,260,545 (402)

Temperature-Sensitive Hydrogels as Carriers for Modulated Delivery of Acetaminophen

open access: yesGels, 2023
The purposes of this study are the polymerization of temperature-sensitive copolymers based on N-isopropyl acrylamide and 10 mol % of 2-hydroxypropylmethacrylate, characterisations of their thermal, morphological and swelling properties, as well as the ...
Snežana Ilić-Stojanović   +5 more
doaj   +1 more source

Association of ABCB1, 5-HT3B receptor and CYP2D6 genetic polymorphisms with ondansetron and metoclopramide antiemetic response in Indonesian cancer patients treated with highly emetogenic chemotherapy. [PDF]

open access: yes, 2011
Our study shows that in Indonesian cancer patients treated with highly cytostatic emetogenic, carriership of the CTG haplotype of the ABCB1 gene is related to an increased risk of delayed chemotherapy-induced nausea and ...
Baak-Pablo, Renee F   +8 more
core   +2 more sources

Self-propelled gas nanomotor-integrated microneedles for melanoma therapy: Dual-action in situ eradication and metastatic suppression

open access: yesMaterials Today Bio
Skin cancer, particularly malignant melanoma, is one of the most prevalent cancers globally, affecting millions annually. Traditional treatments like excision, chemotherapy, and immunotherapy often fail due to their invasiveness, toxicity, and poor drug ...
Chungchi Lee   +9 more
doaj   +1 more source

Controlled-release neurotensin-loaded silk fibroin dressings improve wound healing in diabetic rat model

open access: yesBioactive Materials, 2019
Diabetic foot ulcers (DFU), which may lead to lower extremity amputation, is one of the severe and chronic complications of diabetic mellitus. This study aims to develop, and use dressings based on Silk fibroin (SF) as the scaffold material, gelatin ...
Jianghui Liu   +7 more
doaj   +1 more source

Review of commercially available nano-drugs and nano-delivery systems: challenges and perspectives

open access: yes4 open, 2023
Nano-drugs and nano-delivery systems are rapidly evolving, with new strategies emerging in the current practices. The evolution of these technologies began with modifying the chemical structure, progressing to supramolecular ionic complexes, and ...
Boudovitch Dmitri   +4 more
doaj   +1 more source

Use of single-chain antibody derivatives for targeted drug delivery [PDF]

open access: yes, 2016
Single-chain antibodies (scFvs), which contain only the variable domains of full-length antibodies, are relatively small molecules that can be used for selective drug delivery.
Ahmadzadeh, V.   +5 more
core   +1 more source

AuNPs as an important inorganic nanoparticle applied in drug carrier systems

open access: yesArtificial Cells Nanomedicine and Biotechnology, 2019
Gold nanoparticles (AuNPs), as a kind of inorganic nanoparticle, have been gradually recognized as one of the most promising nanomaterials, which is attributed to their unique optical, electronic, sensing and biochemical characteristics.
Wen Li   +8 more
semanticscholar   +1 more source

Biomaterial-based oral repair membranes: current advances, functional attributes, and future directions

open access: yesMaterials & Design
Oral repair membranes, as biomaterials specifically engineered for the oral environment, demonstrate considerable promise for treating prevalent oral conditions such as pulpitis, tooth loss, oral mucosal defects and periodontal disease.
Lizhi Zeng   +5 more
doaj   +1 more source

Charge Regulation of Self-Assembled Tubules by Protonation for Efficiently Selective and Controlled Drug Delivery

open access: yesiScience, 2019
Summary: Despite the success for targeted delivery in the body, the efficient release without side effects caused by residual drug remains a challenge.
Liping Huang   +12 more
doaj   +1 more source

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale   +6 more
wiley   +1 more source

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