Results 51 to 60 of about 488,754 (242)

The dissolution and solid-state behaviours of coground ibuprofen–glucosamine HCl [PDF]

, 2014
The cogrinding technique is one of most effective methods for improving the dissolution of poorly water-soluble drugs and it is superior to other approaches from an economical as well as an environmental standpoint, as the technique does not require any ...
Ali Nokhodchi, Barzegar-Jalali M, Clegg DO, Ford JL, Hiba Al-Hamidi, Horton D, Kofi Asare-Addo, Mike Kitson, Sandip Desai   +8 more
core   +1 more source

Nanostructured Lipid Carriers: A potential drug carrier for cancer chemotherapy [PDF]

Lipids in Health and Disease, 2012
Nanotechnology having developed exponentially, the aim has been on therapeutic undertaking, particularly for cancerous disease chemotherapy. Nanostructured lipid carriers have attracted expanding scientific and commercial vigilance in the last couple of years as alternate carriers for the pharmaceutical consignment, particularly anticancer ...
S. Selvamuthukumar, Ramaiyan Velmurugan
openaire   +4 more sources

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Tamoxifen drug loading solid lipid nanoparticles prepared by hot high pressure homogenization techniques. [PDF]

, 2008
As drug delivery systems Nanoparticulate widely investigated because of many advantages such as smaller size, controlled drug release potential, targeting ability, enhancement of therapeutic efficacy and reduction of toxicity.
Abdelwahab, Siddig Ibrahim, Abdul, Ahmad Bustamam, Abdullah Al-Haj, Nagi Ahmed, Abdullah, Rasedee   +3 more
core   +1 more source

Polyurethane as Carriers of Antituberculosis Drugs [PDF]

, 2012
Polyurethanes (PU) are an important class of polymers that have found many applications as biomaterials due to their excellent physical properties and relatively good biocompatibility. Basically, PU may be produced by two chemical processes: by polycondensation of a diamine with bischloroformates or by reaction between a diol and a diisocyanate.
Yerkesh Batyrbekov, Rinat Iskakov
openaire   +3 more sources

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Reactive-Oxygen-Species-Responsive Drug Delivery Systems: Promises and Challenges [PDF]

, 2018
Given the increasing evidence indicates that many pathological conditions are associated with elevated reactive oxygen species (ROS) levels, there have been growing research efforts focused on the development of ROS-responsive carrier systems because of ...
Allen, Bae, Bates, Baugh, Bildstein, Bio, Brieger, Broaders, Cao, Cao, Cao, Cao, Chen, Chen, Cheng, Chiang, Choi, de Gracia Lux, DeRosa, Detty, Diaz, Duncan, Duncan, Fang, Fu, Gong, Gupta, Hagen, Han, Hao, Hoare, Hoffman, Huttunen, Ian, Jeong, Ka, Kataoka, Kawanishi, Kim, Konan, Kuang, Lee, Lee, Lee, Lee, Li, Li, Liu, Liu, Liu, Liu, Loukogeorgakis, Ma, Ma, Ma, Major Jourden, Marzenell, Min, Muhammad, Muhammad, Mura, Nishikawa, Noh, Oerlemans, Park, Park, Park, Pelicano, Peng, Power-Billard, Qiu, Ren, Rosenholm, Santra, Saravanakumar, Schumacker, Shiino, Shim, Slowing, Slowing, Song, Song, Song, Sorce, Stella, Su, Szatrowski, Torchilin, Trachootham, Vallet-Regí, Vivero-Escoto, Wang, Wang, Wang, Waris, Weinstain, Wilson, Wu, Yan, Yang, Yuan, Zhang   +101 more
core   +2 more sources

Liposomes as Carriers of Anticancer Drugs [PDF]

, 2013
Nanotechnology and nanoscience present a highly positive prospective of bringing benefits to many research areas and applications. Nanosized vehicles have received considerable attention over the past 30 years as pharmaceutical carriers with a wide range of applications, including drug delivery vehicles, adjuvants in vaccinations, signal enhancers ...
Elaine AmaralLeite, Cristiane dos Santos Giuberti, Sávia Caldeira de Araújo Lopes, TalitaGuieiro Ribeiro Rocha, Mônica Cristina de Oliveira, Diego dos Santos Ferreira   +5 more
openaire   +3 more sources

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Potential of a cyclone prototype spacer to improve in vitro dry powder delivery [PDF]

, 2013
Copyright The Author(s) 2013. This article is published with open access at Springerlink.com. This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium ...
A Nair, A Voss, AJ Hickey, AR Clark, C Terzano, CG Thiel, D Ganderton, Darragh Murnane, DI Daniher, Digby D. Symons, EA Matida, F Lavorini, F Lavorini, H Bisgaard, H Bisgaard, H Bisgaard, H Chrystyn, Irene Parisini, JP Mitchell, K Demirkan, K Svartengren, L Borgstrom, L Borgström, LI Harrison, M Hindle, MEAC Broeders, ML Everard, N Islam, P Begat, PW Barry, R Buhl, R Pauwels, RAM Al-Showair, Sean J. Cheng, SP Newman, T Ehtezazi, T Srichana, T Srichana, WES Kamin, WH DeHaan, WY Tarsin, XM Zeng   +41 more
core   +1 more source