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Degradable Drug Carriers: Vanishing Mesoporous Silica Nanoparticles
Chemistry of Materials, 2019The versatile potential of mesoporous silica nanoparticles (MSNs) as drug delivery agents for cytotoxic or chemically sensitive (macro)molecules has been demonstrated in numerous in vitro and in vi...
K. Möller, T. Bein
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Microemulsions as carriers for drugs and nutraceuticals
Advances in Colloid and Interface Science, 2006Microemulsions are potentially excellent carriers for bioactive molecules. They offer the advantage of spontaneous formation, ease of manufacture, thermodynamic stability, and improved solubilization of bioactive materials. This review explores some of the new trends in microemulsion research through analysis of some representative studies.
Aviram Spernath, Abraham Aserin
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Polymeric microspheres as drug carriers
Biomaterials, 1988The use of polymeric microsphere systems (including polypeptides) as vehicles for delivering drugs by a variety of routes is considered with particular reference to parenteral administration. Microsphere formulation is discussed with emphasis on the role of surface properties and how these can determine the fate of administered particles.
Stanley S. Davis, Lisbeth Illum
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Magnetic iron oxide nanoparticles as drug carriers: preparation, conjugation and delivery.
Nanomedicine, 2018Magnetic nanoparticles (MNPs), particularly made of iron oxides, have been extensively studied as diagnostic imaging agents and therapeutic delivery vehicles.
Kheireddine El-Boubbou
semanticscholar +1 more source
ChemInform Abstract: Cyclodextrin Drug Carrier Systems
ChemInform, 1998AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Fumitoshi Hirayama +2 more
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Magnetic iron oxide nanoparticles as drug carriers: clinical relevance.
Nanomedicine, 2018Significant preclinical and clinical research has explored the use of magnetic iron oxide nanoparticles (MNPs) for medical theranostics. Herein, we provide an overview of the optimal 'design-to-perform' MNPs used in cancer therapeutics, specifically ...
Kheireddine El-Boubbou
semanticscholar +1 more source
Nanoscale, 2017
The oral pathway is considered as the most common method for drug administration, although many drugs, especially the highly pH- and/or enzymatic biodegradable peptide drugs, are very difficult to formulate and achieve a good intestinal absorption ...
J. Florek, R. Caillard, F. Kleitz
semanticscholar +1 more source
The oral pathway is considered as the most common method for drug administration, although many drugs, especially the highly pH- and/or enzymatic biodegradable peptide drugs, are very difficult to formulate and achieve a good intestinal absorption ...
J. Florek, R. Caillard, F. Kleitz
semanticscholar +1 more source
Driving forces for drug loading in drug carriers
Journal of Microencapsulation, 2015The loading capacity of a drug carrier is determined essentially by intermolecular interactions between drugs and carrier materials. In this review, the process of drug loading is described in detail based on the differences in the driving force for drug incorporation, including hydrophobic interaction, electrostatic interaction, hydrogen bonding, Pi ...
Yang Li, Li Yang
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Application of dextran as nanoscale drug carriers.
Nanomedicine, 2018Dextran is a kind of biocompatible, nontoxic and nonimmunogenic biological substance that has been widely used in drug-delivery systems. With further research and understanding of dextran and its derivatives, people can more precisely control the ...
G. Huang, Hualiang Huang
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Molecular Pharmaceutics, 2018
We have performed two sets of all atom molecular dynamics (MD) simulations of poly(acrylic acid) (PAA) oligomers, considered as a model pH-responsive drug carrier. In the first set, multiple oligomers of PAA are simulated in model gastric and intestinal fluids, where the degree of deprotonation of PAA oligomers is varied with the medium pH.
Ratna S. Katiyar, Prateek K. Jha
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We have performed two sets of all atom molecular dynamics (MD) simulations of poly(acrylic acid) (PAA) oligomers, considered as a model pH-responsive drug carrier. In the first set, multiple oligomers of PAA are simulated in model gastric and intestinal fluids, where the degree of deprotonation of PAA oligomers is varied with the medium pH.
Ratna S. Katiyar, Prateek K. Jha
openaire +3 more sources