Results 301 to 310 of about 429,667 (356)
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Life Sciences, 1977
Abstract The use of liposomes as drug carrying vehicles are summarized. Introduction of smaller doses, increased permeability, reduced toxicological and allergic effects and altered immunological responses are the advantages of the method. Experimental techniques for the preparation of drug containing liposomes and for their deliveries are surveyed ...
J H, Fendler, A, Romero
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Abstract The use of liposomes as drug carrying vehicles are summarized. Introduction of smaller doses, increased permeability, reduced toxicological and allergic effects and altered immunological responses are the advantages of the method. Experimental techniques for the preparation of drug containing liposomes and for their deliveries are surveyed ...
J H, Fendler, A, Romero
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Drug carriers for vascular drug delivery
IUBMB Life, 2011AbstractThe currently used drug carriers for vascular drug delivery are reviewed. The human vascular system possesses unique physiological features that can be exploited for enhanced and effective targeted drug delivery. Although the thin layer of endothelial cells (EC) lines the interior surface of blood vessels forming an interface between ...
Erez, Koren, Vladimir P, Torchilin
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Engineering in Medicine, 1986
Site-specific drug carriers are required to exclusively deliver drug molecules to difficult targets within the body. They should do so in a form which protects the drug and host from one another. This contribution reviews the reasons for drug targeting, and describes some of the features required of two types of carrier system, i.e., particulates and ...
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Site-specific drug carriers are required to exclusively deliver drug molecules to difficult targets within the body. They should do so in a form which protects the drug and host from one another. This contribution reviews the reasons for drug targeting, and describes some of the features required of two types of carrier system, i.e., particulates and ...
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Carrier Deformability in Drug Delivery
Current Pharmaceutical Design, 2016Deformability is a key property of drug carriers used to increase the mass penetration across the skin without disrupting the lipid barrier. Highly deformable vesicles proved to be more effective than conventional liposomes in delivering drugs into and across the mammalian skin upon topical non occlusive application.
Morilla, María José +1 more
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Polymeric microspheres as drug carriers
Biomaterials, 1988The use of polymeric microsphere systems (including polypeptides) as vehicles for delivering drugs by a variety of routes is considered with particular reference to parenteral administration. Microsphere formulation is discussed with emphasis on the role of surface properties and how these can determine the fate of administered particles.
S S, Davis, L, Illum
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Albumin-Based Nanodevices as Drug Carriers
Current Pharmaceutical Design, 2016Nanomedicine, the application of nanotechnology to medicine, is being increasingly used to improve and exploit the advantages of efficient drug delivery. Different nanodevices have been developed in recent years, among them protein-based nanoparticles which have gained considerable interest.
Loureiro, Ana Isabel Sá +3 more
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Driving forces for drug loading in drug carriers
Journal of Microencapsulation, 2015The loading capacity of a drug carrier is determined essentially by intermolecular interactions between drugs and carrier materials. In this review, the process of drug loading is described in detail based on the differences in the driving force for drug incorporation, including hydrophobic interaction, electrostatic interaction, hydrogen bonding, Pi ...
Yang, Li, Li, Yang
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Peptide vectors as drug carriers
2003During the last decade, several peptides have been described, such as SynB vectors [1] penetratin and Tat [2, 3] that allow the intracellular delivery of polar, biologically active compounds in vitro and in vivo [2, 4]. These peptides, belonging to various families, are heterogeneous in size (10 to 18 amino acids) and sequence (Tab. 1).
Jamal, Temsamani +1 more
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Microparticulate Drug Carriers
1985Several type of microparticulate carriers have been employed in recent years in conjunction with a wide variety of drugs and a broad range of therapeutic goals. One of the most salient characteristics of microparticulate materials as drug carriers is that, in general, the drug-carrrier complex must be administered parenterally, usually by intravenous ...
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Cyclodextrin Drug Carrier Systems
Chemical Reviews, 1998Kaneto, Uekama +2 more
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