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Peptide vectors as drug carriers
2003During the last decade, several peptides have been described, such as SynB vectors [1] penetratin and Tat [2, 3] that allow the intracellular delivery of polar, biologically active compounds in vitro and in vivo [2, 4]. These peptides, belonging to various families, are heterogeneous in size (10 to 18 amino acids) and sequence (Tab. 1).
Jean-Michel Scherrmann, Jamal Temsamani
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Engineering in Medicine, 1986
Site-specific drug carriers are required to exclusively deliver drug molecules to difficult targets within the body. They should do so in a form which protects the drug and host from one another. This contribution reviews the reasons for drug targeting, and describes some of the features required of two types of carrier system, i.e., particulates and ...
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Site-specific drug carriers are required to exclusively deliver drug molecules to difficult targets within the body. They should do so in a form which protects the drug and host from one another. This contribution reviews the reasons for drug targeting, and describes some of the features required of two types of carrier system, i.e., particulates and ...
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Drug carriers in osteoporosis: Preparation, drug encapsulation and applications
International Journal of Pharmaceutics, 2013Carriers are largely used to enhance therapy efficiency via the encapsulation of active molecules. The encapsulation enhances the stability of drug molecules, improves the targeting properties and prolongs pharmacological activity via continuous local release of active molecules.
Miladi, K.+3 more
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Exploration of Macroporous Polymeric Sponges As Drug Carriers.
Biomacromolecules, 2017Achieving high drug loading capacity and controlling drug delivery are two main challenges related to drug carriers. In this study, polymeric macroporous sponges with very high pore volume and large porosity are introduced as a new-type of drug carrier ...
Gaigai Duan+5 more
semanticscholar +1 more source
Cyclodextrin polymers: Structure, synthesis, and use as drug carriers
Progress in polymer science, 2021Zongjian Liu+4 more
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2010
Beads are often used as drug carriers in passive, as well as active drug targeting, making this a highly relevant topic in today’s research. Major general topics covered in the first part of this chapter include controlled drug release, gels in drug-delivery systems, dual- drug-loaded beads, and drug release from the beads.
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Beads are often used as drug carriers in passive, as well as active drug targeting, making this a highly relevant topic in today’s research. Major general topics covered in the first part of this chapter include controlled drug release, gels in drug-delivery systems, dual- drug-loaded beads, and drug release from the beads.
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Lipid Formulation as a Drug Carrier for Drug Delivery
Current Pharmaceutical Design, 2002In recent years, a Drug Delivery System (DDS), a preparative approach attracts the attention in the development of new drugs. DDS focuses on the regulation of the in vivo dynamics, such as absorption, distribution, metabolism, and elimination, thereby improving the effectiveness and the safety of the drugs by an applicable use of drug preparation ...
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Nanoparticulates as Drug Carriers
2006Nanoparticle Flow: Implications for Drug Delivery (A T Florence) Polymer Micelles as Drug Carriers (E V Batrakova et al.) Lipoproteins as Pharmaceutical Carriers (S Liu et al.) Dendrimers as Nanoparticular Drug Carriers (S Svenson & D A Tomalia) Cells and Cell Ghosts as Drug Carriers (J M Lanao & M L Sayalero) Magnetic Nanoparticles as Drug Carriers (U
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Microparticulate Drug Carriers
1985Several type of microparticulate carriers have been employed in recent years in conjunction with a wide variety of drugs and a broad range of therapeutic goals. One of the most salient characteristics of microparticulate materials as drug carriers is that, in general, the drug-carrrier complex must be administered parenterally, usually by intravenous ...
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Vesicular carriers for dermal drug delivery
Expert Opinion on Drug Delivery, 2009The skin can offer several advantages as a route of drug administration although its barrier nature makes it difficult for most drugs to penetrate into and permeate through it. During the past decades there has been a lot of interest in lipid vesicles as a tool to improve drug topical delivery.
Sinico C, FADDA, ANNA MARIA
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