Results 121 to 130 of about 2,161,716 (285)
Objective Routine liver enzyme monitoring is advocated for while on allopurinol, but supporting guidance is lacking. We assessed the incidence and factors associated with elevated liver enzyme levels in patients with gout commenced on allopurinol. Methods One hundred and fifty patients with gout and normal baseline serum aminotransferases initiated on ...
May Shuen Tang +4 more
wiley +1 more source
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi +10 more
wiley +1 more source
Objective The objective of this study was to evaluate the real‐world effectiveness and safety of secukinumab in patients with giant cell arteritis (GCA). Methods This multicenter retrospective study included patients with GCA who received secukinumab at 14 Italian centers with at least six months of follow‐up.
Luca Iorio +28 more
wiley +1 more source
Beyond a spec: assessing heterogeneity in the unregulated opioid supply
Background Drug checking services aim to provide compositional information for the illicit drug supply and are being employed in public health responses to extreme rates of overdose associated with fentanyl within street opioids.
Lea Gozdzialski +9 more
doaj +1 more source
Objective Reproductive‐age women with systemic autoimmune and rheumatic diseases (SARDs) have unique information needs related to their SARDs and reproductive health. We sought to understand their use of and receptivity to current and hypothetical generative artificial intelligence (AI) tools for health information‐seeking. Methods We conducted a cross‐
Mariam Arif +5 more
wiley +1 more source
Objectives This study aimed to determine whether gout flare resolution is associated with physical activity and sleep. These findings were intended to inform the future development of a definition for flare resolution. Methods Data from 81 participants with gout who experienced >1 flare during a 6‐month prospective observational study were included ...
Sarah Stewart +12 more
wiley +1 more source
Abstract Accurate, user-friendly drug checking tools are critical in reducing overdose risks, especially in settings where people test substances without professional guidance. This study examined whether a small design change—a 10mg micro scoop—could improve how users interact with fentanyl test kits. During a multi-day music festival,
Annastasia R. Beal, Bryce Batcheller
openaire +1 more source
BackgroundOverdose deaths continue to reach new records in New York City and nationwide, largely driven by adulterants such as fentanyl and xylazine in the illicit drug supply.
Ian David Aronson +3 more
doaj +1 more source
Generative AI in clinical practice: how should rheumatologists evaluate and monitor emerging tools?
Generative artificial intelligence (AI) is increasingly being used in rheumatology practice, to assist with tasks such as documentation, record summarization, and clinical decision support. Rheumatologists need a practical approach to determining what evidence and oversight each application requires.
Koushan Kouranloo +2 more
wiley +1 more source
Background In response to the overdose crisis, a collaborative group of two community-based organizations, a health authority and a research institute in Vancouver, Canada, implemented a pilot community-based drug checking (CBDC) intervention for sexual ...
Pierre-julien Coulaud +6 more
doaj +1 more source

